PMID- 34660164
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211027
IS  - 2146-1414 (Print)
IS  - 2147-1959 (Electronic)
IS  - 2146-1414 (Linking)
VI  - 30
IP  - 3
DP  - 2021 Oct 15
TI  - Radium-223 Treatment in mCRPC Patient with Polycythemia Vera.
PG  - 193-196
LID - 10.4274/mirt.galenos.2020.58661 [doi]
AB  - There have been several studies on the clinical outcomes of Radium-223 treatment 
      in patients with metastatic castration-resistant prostate cancer (mCRPC) who may 
      have an increased risk of hematologic comorbidities. To the best of our 
      knowledge, this is the first study to explore the potential bone marrow adverse 
      effects (AEs) of Radium-223 administered with specific drugs used for hematologic 
      conditions, such as polycythemia vera (PV). We report the case of a patient with 
      mCRPC who was administered a combined treatment of Radium-223 and hydroxyurea for 
      PV, aiming to support clinicians in predicting eventual AEs.
FAU - de Angelis, Cristina
AU  - de Angelis C
AUID- ORCID: 0000-0003-0638-3463
AD  - Sapienza University of Rome, Department of Radiological Sciences, Oncology and 
      Anatomical Pathology, Rome, Italy
FAU - Frantellizzi, Viviana
AU  - Frantellizzi V
AUID- ORCID: 0000-0003-3497-4236
AD  - Sapienza University of Rome, Department of Radiological Sciences, Oncology and 
      Anatomical Pathology, Rome, Italy
FAU - Pontico, Mariano
AU  - Pontico M
AUID- ORCID: 0000-0001-6143-4775
AD  - apienza University of Rome, Ph.D. Program in Morphogenesis and Tissue 
      Engineering, Department of Medico-surgical Sciences and Biotechnologies, Rome, 
      Italy
FAU - de Feo, Maria Silvia
AU  - de Feo MS
AUID- ORCID: 0000-0003-3216-4838
AD  - Sapienza University of Rome, Department of Radiological Sciences, Oncology and 
      Anatomical Pathology, Rome, Italy
FAU - Lazri, Julia
AU  - Lazri J
AUID- ORCID: 0000-0002-1566-2416
AD  - Sapienza University of Rome, Department of Radiological Sciences, Oncology and 
      Anatomical Pathology, Rome, Italy
FAU - de Vincentis, Giuseppe
AU  - de Vincentis G
AUID- ORCID: 0000-0003-4690-1528
AD  - Sapienza University of Rome, Department of Radiological Sciences, Oncology and 
      Anatomical Pathology, Rome, Italy
LA  - eng
PT  - Journal Article
PL  - Turkey
TA  - Mol Imaging Radionucl Ther
JT  - Molecular imaging and radionuclide therapy
JID - 101584839
PMC - PMC8522512
OTO - NOTNLM
OT  - Prostate cancer
OT  - Radium-223
OT  - hematogical toxicity
OT  - mCRPC
OT  - polycythemia vera
COIS- Conflict of Interest: No conflict of interest was declared by the authors.
EDAT- 2021/10/19 06:00
MHDA- 2021/10/19 06:01
PMCR- 2021/10/01
CRDT- 2021/10/18 09:04
PHST- 2021/10/18 09:04 [entrez]
PHST- 2021/10/19 06:00 [pubmed]
PHST- 2021/10/19 06:01 [medline]
PHST- 2021/10/01 00:00 [pmc-release]
AID - 49281 [pii]
AID - 10.4274/mirt.galenos.2020.58661 [doi]
PST - ppublish
SO  - Mol Imaging Radionucl Ther. 2021 Oct 15;30(3):193-196. doi: 
      10.4274/mirt.galenos.2020.58661.