PMID- 34661921
OWN - NLM
STAT- MEDLINE
DCOM- 20220411
LR  - 20220411
IS  - 1522-2683 (Electronic)
IS  - 0173-0835 (Linking)
VI  - 43
IP  - 3
DP  - 2022 Feb
TI  - Single bubble in-tube microextraction coupled with capillary electrophoresis.
PG  - 456-463
LID - 10.1002/elps.202100216 [doi]
AB  - Headspace (HS) extraction is a sample pretreatment technique for volatile and 
      semivolatile organic compounds in a complex matrix. Recently, in-tube 
      microextraction (ITME) coupled with CE using an acceptor plug placed in the 
      capillary inlet was developed as a simple but powerful HS extraction method. 
      Here, we present single bubble (SB) ITME using a bubble hanging to the capillary 
      inlet immersed in a sample donor solution as a HS of submicroliter volume ( approximately 200 
      nL). The analytes evaporated to the bubble were extracted into the acceptor phase 
      through the capillary opening, then electrophoresis of the enriched extract was 
      carried out. Since the bubble volume was much smaller than a conventional HS 
      volume ( approximately 1 mL), it was filled with the evaporated analytes rapidly and the 
      analytes could be enriched much faster compared to conventional HS-ITME. Owing to 
      the high surface-to-volume ratio of the SB, 5 min SB-ITME yielded the enrichment 
      factor values similar to those of 10 min HS-ITME. When 5 min SB-ITME at room 
      temperature was applied to a tap water sample, the enrichment factors of 
      2,4,6-trichlorophenol (TCP), 2,3,6-TCP, and 2,6-dichlorophenol were 53, 41, and 
      60, respectively, and the LOQs obtained by monitoring the absorbance at 214 nm 
      were 5.6-8.3 ppb, much lower than 200 ppb, the World Health Organization 
      guideline for the maximum permissible concentration of 2,4,6-TCP in drinking 
      water.
CI  - (c) 2021 Wiley-VCH GmbH.
FAU - Jeong, Sunkyung
AU  - Jeong S
AD  - Department of Chemistry, Seoul National University, Seoul, Korea.
FAU - Noulorsaytour, Xamyo
AU  - Noulorsaytour X
AD  - Department of Chemistry, Seoul National University, Seoul, Korea.
FAU - Valdez, Joseph E
AU  - Valdez JE
AD  - Department of Chemistry, Seoul National University, Seoul, Korea.
AD  - Department of Natural Sciences, College of Arts and Sciences, Nueva Vizcaya State 
      University, Bayombong, Philippines.
FAU - Chung, Doo Soo
AU  - Chung DS
AUID- ORCID: 0000-0002-8335-3201
AD  - Department of Chemistry, Seoul National University, Seoul, Korea.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20211105
PL  - Germany
TA  - Electrophoresis
JT  - Electrophoresis
JID - 8204476
RN  - 0 (Chlorophenols)
RN  - 0 (Drinking Water)
RN  - 0 (Organic Chemicals)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - *Chlorophenols/analysis
MH  - *Drinking Water
MH  - Electrophoresis, Capillary/methods
MH  - *Liquid Phase Microextraction
MH  - Organic Chemicals/analysis
MH  - *Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Capillary electrophoresis
OT  - Chlorophenols
OT  - Headspace extraction
OT  - In-tube microextraction
OT  - Single bubble in-tube microextraction
EDAT- 2021/10/19 06:00
MHDA- 2022/04/12 06:00
CRDT- 2021/10/18 12:42
PHST- 2021/10/11 00:00 [revised]
PHST- 2021/07/12 00:00 [received]
PHST- 2021/10/13 00:00 [accepted]
PHST- 2021/10/19 06:00 [pubmed]
PHST- 2022/04/12 06:00 [medline]
PHST- 2021/10/18 12:42 [entrez]
AID - 10.1002/elps.202100216 [doi]
PST - ppublish
SO  - Electrophoresis. 2022 Feb;43(3):456-463. doi: 10.1002/elps.202100216. Epub 2021 
      Nov 5.