PMID- 34665562 OWN - NLM STAT- MEDLINE DCOM- 20211021 LR - 20211021 IS - 0869-866X (Print) IS - 0869-866X (Linking) VI - 29 IP - 5 DP - 2021 Sep TI - [The impact of re-vaccination implementation on morbidity of mumps in the Kyrgyz Republic]. PG - 1220-1224 LID - 10.32687/0869-866X-2021-29-5-1220-1224 [doi] AB - The article presents results of evaluation of long-term dynamics of morbidity of mumps in the Kyrgyz Republic (KR) in the pre-vaccination period, after the introduction of routine mass immunization in 1978 and in beginning of re-vaccination since 2015. The pronounced trend of increasing of morbidity was noted since 1970. In 1978, the morbidity increased up to 194 times as compared to 1948. The annual growth rate was made up to 7.7%. The application of vaccination significantly effected morbidity and prevalence of mumps in the Republic. In the long-term dynamics a pronounced trend of morbidity decreasing with annual decreasing rate of 7.5%. In 2015, re-vaccination of children of 6 years old was introduced in the Republic. This action resulted in morbidity decreasing during the next three years (2016, 2017 and 2018). However, in 2019, an outbreak of morbidity covering both children under 14 years and the adults was registered. The level of IgG to virus of mumps was determined by enzyme-linked immunosorbent assay using the test-system "VectoParotit-IgG" (by Vector BEST, Russia). The analysis of seroepidemiological study established the highest specific weight of seronegative individuals in the age group of 1-4 years (51.5%, 95% CI 42.9-60.1), and proportion of seropositive individuals falls on the age groups of 30 years and over (85, 4%), 10-14 years (62%), 5-9 years (61.5%), 15-19 years (60%). FAU - Niiazalieva, M S AU - Niiazalieva MS AD - The I. K. Akhunbaev Kyrgyz State Medical Academy, 720020, Bishkek, the Kyrgyz Republic, niyazalieva_mira@mail.ru. FAU - Isakova, Zh T AU - Isakova ZT AD - The I. K. Akhunbaev Kyrgyz State Medical Academy, 720020, Bishkek, the Kyrgyz Republic. FAU - Toygombaeva, V S AU - Toygombaeva VS AD - The I. K. Akhunbaev Kyrgyz State Medical Academy, 720020, Bishkek, the Kyrgyz Republic. FAU - Aldjambaeva, I Sh AU - Aldjambaeva IS AD - The I. K. Akhunbaev Kyrgyz State Medical Academy, 720020, Bishkek, the Kyrgyz Republic. LA - rus PT - Journal Article PL - Russia (Federation) TA - Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med JT - Problemy sotsial'noi gigieny, zdravookhraneniia i istorii meditsiny JID - 101270373 RN - 0 (Antibodies, Viral) SB - IM MH - Adult MH - Antibodies, Viral MH - Child MH - Child, Preschool MH - Humans MH - Infant MH - Kyrgyzstan/epidemiology MH - *Mumps/epidemiology/prevention & control MH - Prevalence MH - Vaccination OTO - NOTNLM OT - antibodies OT - mumps OT - population immunity OT - post-vaccination immunity OT - serological monitoring EDAT- 2021/10/20 06:00 MHDA- 2023/02/25 06:00 CRDT- 2021/10/19 12:41 PHST- 2021/03/21 00:00 [received] PHST- 2021/06/27 00:00 [accepted] PHST- 2021/10/19 12:41 [entrez] PHST- 2021/10/20 06:00 [pubmed] PHST- 2023/02/25 06:00 [medline] AID - 10.32687/0869-866X-2021-29-5-1220-1224 [doi] PST - ppublish SO - Probl Sotsialnoi Gig Zdravookhranenniiai Istor Med. 2021 Sep;29(5):1220-1224. doi: 10.32687/0869-866X-2021-29-5-1220-1224.