PMID- 34669109
OWN - NLM
STAT- MEDLINE
DCOM- 20220411
LR  - 20221207
IS  - 1708-0428 (Electronic)
IS  - 0960-8923 (Linking)
VI  - 32
IP  - 1
DP  - 2022 Jan
TI  - Five-Year Outcomes of Sleeve Gastrectomy in Patients with Class I Obesity and 
      Type 2 Diabetes Mellitus.
PG  - 96-102
LID - 10.1007/s11695-021-05718-x [doi]
AB  - BACKGROUND: Several studies have reported short and medium-term outcomes of 
      laparoscopic sleeve gastrectomy (LSG) in patients with class I obesity and type 2 
      diabetes mellitus (T2DM). However, literature on outcomes beyond three years is 
      scarce. The present study discusses the 5-year results of a previously reported 
      cohort of 20 patients with class I obesity and T2DM, who had undergone LSG 
      between March 2012 and March 2015. MATERIALS AND METHODS: Patients were followed 
      up in the bariatric clinic at yearly intervals as per institute protocol. Primary 
      outcome was proportion of patients with a glycated haemoglobin (HbA1c) level of 
      6.5% or less, 5 years after LSG. Secondary outcomes were percentage total weight 
      loss (%TWL), excess weight loss (EWL), weight regain and complications. RESULTS: 
      Out of 20 patients, 9 (45%) were male and 11 (55%) were female. Mean age was 
      41.6 +/- 9.5 years. Mean pre-operative weight and BMI were 94.8 +/- 14.4 kg and 
      33.4 +/- 1.2 kg/m(2), respectively. Median duration of diabetes was 42 months. Mean 
      pre-operative fasting plasma glucose (FPG) and HbA1c were 171.1 +/- 56.8 mg/dL and 
      8.7 +/- 1.6%, respectively. Of the 17 patients available for follow-up at 5 years, 
      9 (52.9%) achieved HbA1c < 6.5% without medication, while 7 (41.2%) patients had 
      improvement of their glycaemic status. One patient had recurrence of diabetes 
      after initial remission. Mean %TWL and %EWL were 18% and 65.1%, respectively. 
      CONCLUSION: Laparoscopic sleeve gastrectomy is a reasonable option as a metabolic 
      procedure for patients with T2DM and class I obesity.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Science+Business 
      Media, LLC, part of Springer Nature.
FAU - Singh, Devender
AU  - Singh D
AD  - Department of Surgical Disciplines, All India Institute of Medical Sciences, Room 
      No. 5034, New Delhi, India.
FAU - Baksi, Aditya
AU  - Baksi A
AD  - Department of General Surgery, All India Institute of Medical Sciences, Jodhpur, 
      India.
FAU - Ramana, Prasanna
AU  - Ramana P
AD  - Department of Surgical Disciplines, All India Institute of Medical Sciences, Room 
      No. 5034, New Delhi, India.
FAU - Singla, Vitish
AU  - Singla V
AD  - Department of Surgical Disciplines, All India Institute of Medical Sciences, Room 
      No. 5034, New Delhi, India.
FAU - Aggarwal, Sandeep
AU  - Aggarwal S
AUID- ORCID: 0000-0001-9540-0303
AD  - Department of Surgical Disciplines, All India Institute of Medical Sciences, Room 
      No. 5034, New Delhi, India. sandeep_aiims@yahoo.co.in.
LA  - eng
PT  - Journal Article
DEP - 20211020
PL  - United States
TA  - Obes Surg
JT  - Obesity surgery
JID - 9106714
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Adult
MH  - *Diabetes Mellitus, Type 2/complications/surgery
MH  - Female
MH  - Gastrectomy/methods
MH  - Glycated Hemoglobin/metabolism
MH  - Humans
MH  - *Laparoscopy/methods
MH  - Male
MH  - Middle Aged
MH  - Obesity/surgery
MH  - *Obesity, Morbid/surgery
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Weight Loss
OTO - NOTNLM
OT  - Bariatric surgery
OT  - Long-term outcomes
OT  - Metabolic surgery
OT  - Non-severe obesity
OT  - T2DM
EDAT- 2021/10/21 06:00
MHDA- 2022/04/12 06:00
CRDT- 2021/10/20 12:32
PHST- 2021/07/08 00:00 [received]
PHST- 2021/09/22 00:00 [accepted]
PHST- 2021/09/03 00:00 [revised]
PHST- 2021/10/21 06:00 [pubmed]
PHST- 2022/04/12 06:00 [medline]
PHST- 2021/10/20 12:32 [entrez]
AID - 10.1007/s11695-021-05718-x [pii]
AID - 10.1007/s11695-021-05718-x [doi]
PST - ppublish
SO  - Obes Surg. 2022 Jan;32(1):96-102. doi: 10.1007/s11695-021-05718-x. Epub 2021 Oct 
      20.