PMID- 34674507 OWN - NLM STAT- MEDLINE DCOM- 20211115 LR - 20221207 IS - 2093-5978 (Electronic) IS - 2093-596X (Print) IS - 2093-596X (Linking) VI - 36 IP - 5 DP - 2021 Oct TI - Year-Long Trend in Glycated Hemoglobin Levels in Patients with Type 2 Diabetes during the COVID-19 Pandemic. PG - 1142-1146 LID - 10.3803/EnM.2021.1154 [doi] AB - It has been suggested that the coronavirus disease 2019 (COVID-19) pandemic has had a negative impact on glycemic control in patients with type 2 diabetes mellitus (T2DM). However, no study has examined yearly trends in glycated hemoglobin (HbA1c) levels after the start of the COVID-19 outbreak. Here, we performed a retrospective analysis of HbA1c concentrations during the early period of the COVID-19 outbreak (COVID-19 cohort) and then compared the yearly trend in the mean HbA1c level, along with fluctuations in HbA1c levels, with those during previous years (non-COVID-19 cohorts). We observed that the mean HbA1c level in patients with T2DM increased during the first 6 months of the COVID-19 outbreak. After 6 months, HbA1c levels in the COVID-19 cohort returned to levels seen in the non-COVID-19 cohorts. The data suggest that vulnerable patients with T2DM should be monitored closely during the early period of a pandemic to ensure they receive appropriate care. FAU - Jin, Jonghwa AU - Jin J AD - Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Lee, Seong Wook AU - Lee SW AD - Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Lee, Won-Ki AU - Lee WK AD - Center of Biostatistics, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Jeon, Jae-Han AU - Jeon JH AD - Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Kim, Jung-Guk AU - Kim JG AD - Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Lee, In-Kyu AU - Lee IK AD - Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Choi, Yeon-Kyung AU - Choi YK AD - Department of Internal Medicine, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. FAU - Park, Keun-Gyu AU - Park KG AD - Department of Internal Medicine, Kyungpook National University Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. LA - eng GR - Kyungpook National University Hospital/ PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20211021 PL - Korea (South) TA - Endocrinol Metab (Seoul) JT - Endocrinology and metabolism (Seoul, Korea) JID - 101554139 RN - 0 (Blood Glucose) RN - 0 (Glycated Hemoglobin A) SB - IM MH - Adult MH - Blood Glucose/analysis MH - COVID-19/diagnosis/*epidemiology/virology MH - Case-Control Studies MH - Diabetes Mellitus, Type 2/*blood/epidemiology MH - Disease Outbreaks/statistics & numerical data MH - Female MH - Glycated Hemoglobin/*analysis MH - Glycemic Control/*trends MH - Humans MH - Male MH - Retrospective Studies MH - SARS-CoV-2/genetics MH - Time Factors PMC - PMC8566134 OTO - NOTNLM OT - COVID-19 OT - Diabetes mellitus OT - Glycated hemoglobin A OT - Physical distancing COIS- CONFLICTS OF INTEREST No potential conflict of interest relevant to this article was reported. EDAT- 2021/10/23 06:00 MHDA- 2021/11/16 06:00 PMCR- 2021/10/01 CRDT- 2021/10/22 01:13 PHST- 2021/06/14 00:00 [received] PHST- 2021/09/10 00:00 [accepted] PHST- 2021/10/23 06:00 [pubmed] PHST- 2021/11/16 06:00 [medline] PHST- 2021/10/22 01:13 [entrez] PHST- 2021/10/01 00:00 [pmc-release] AID - EnM.2021.1154 [pii] AID - enm-2021-1154 [pii] AID - 10.3803/EnM.2021.1154 [doi] PST - ppublish SO - Endocrinol Metab (Seoul). 2021 Oct;36(5):1142-1146. doi: 10.3803/EnM.2021.1154. Epub 2021 Oct 21.