PMID- 34681314
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211026
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 10
IP  - 10
DP  - 2021 Sep 24
TI  - Occurrence of Pesticide Residues in Spanish Honey Measured by QuEChERS Method 
      Followed by Liquid and Gas Chromatography-Tandem Mass Spectrometry.
LID - 10.3390/foods10102262 [doi]
LID - 2262
AB  - In the current study, the QuEChERS extraction method with slight modifications, 
      followed by liquid and gas chromatography-tandem mass spectrometry, was applied 
      for the determination of 399 pesticide residues in 91 raw honey samples from 
      northeastern Spain. The quality control procedure established in Document No. 
      SANTE/12682/2019 was successfully followed: the responses in reagent blank and 
      blank honey samples were below 30% of the reporting limit (0.01 mg kg(-1)) for 
      all analysed compounds, the correlation coefficients (R(2)) were higher than 0.99 
      in most calibration curves, the deviation of back-calculated concentration from 
      the true concentration was below +/-20% (using the standard of 50 mug L(-1) 
      concentration), and the recoveries of spiked samples on matrix were within the 
      range of 70-120% for almost all analytes. Only chlorfenvinphos (2-7.8 ng/g) and 
      coumaphos (8.8-37 ng/g) were detected in 13 samples, and neither were observed to 
      exceed their maximum residue limits (MRLs). Dietary risk assessment for pesticide 
      residues in honey above their lowest calibrated level (LCL) was performed, and 
      two different age groups, adults and infants, were considered as populations at 
      risk. The contribution of honey lay far below the acceptable daily intake (ADI) 
      for both pesticide residues. Therefore, according to our results, honey is 
      unlikely to pose concerns for consumer health in terms of its contribution to 
      dietary long-term exposure. However, to maintain the level of compliance, 
      pesticide residues in honey should be continuously monitored.
FAU - Lasheras, Roberto Jesus
AU  - Lasheras RJ
AD  - Laboratorio Agroambiental, Unidad Tecnica de Residuos Fitosanitarios, Gobierno de 
      Aragon, Avenida de Montanana 1005, 50071 Zaragoza, Spain.
FAU - Lazaro, Regina
AU  - Lazaro R
AUID- ORCID: 0000-0002-6460-1388
AD  - Instituto Agroalimentario de Aragon-IA2, Veterinary Faculty, Universidad de 
      Zaragoza-CITA, 50013 Zaragoza, Spain.
FAU - Burillo, Juan Carlos
AU  - Burillo JC
AD  - Laboratorio Agroambiental, Unidad Tecnica de Residuos Fitosanitarios, Gobierno de 
      Aragon, Avenida de Montanana 1005, 50071 Zaragoza, Spain.
FAU - Bayarri, Susana
AU  - Bayarri S
AUID- ORCID: 0000-0002-1668-4940
AD  - Instituto Agroalimentario de Aragon-IA2, Veterinary Faculty, Universidad de 
      Zaragoza-CITA, 50013 Zaragoza, Spain.
LA  - eng
GR  - grant Grupo A06-20R/Gobierno de Aragon/
PT  - Journal Article
DEP - 20210924
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC8534991
OTO - NOTNLM
OT  - QuEChERS
OT  - apiculture
OT  - biomonitoring
OT  - environmental pollution
OT  - honey
OT  - pesticides
OT  - risk assessment
COIS- The authors declare no conflict of interest. The funders had no role in the 
      design of the study; in the collection, analyses, or interpretation of data; in 
      the writing of the manuscript; or in the decision to publish the results.
EDAT- 2021/10/24 06:00
MHDA- 2021/10/24 06:01
PMCR- 2021/09/24
CRDT- 2021/10/23 01:07
PHST- 2021/09/01 00:00 [received]
PHST- 2021/09/16 00:00 [revised]
PHST- 2021/09/17 00:00 [accepted]
PHST- 2021/10/23 01:07 [entrez]
PHST- 2021/10/24 06:00 [pubmed]
PHST- 2021/10/24 06:01 [medline]
PHST- 2021/09/24 00:00 [pmc-release]
AID - foods10102262 [pii]
AID - foods-10-02262 [pii]
AID - 10.3390/foods10102262 [doi]
PST - epublish
SO  - Foods. 2021 Sep 24;10(10):2262. doi: 10.3390/foods10102262.