PMID- 34681399
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211026
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 10
IP  - 10
DP  - 2021 Oct 2
TI  - Simultaneous Determination of Albendazole and Its Three Metabolites in Pig and 
      Poultry Muscle by Ultrahigh-Performance Liquid Chromatography-Fluorescence 
      Detection.
LID - 10.3390/foods10102350 [doi]
LID - 2350
AB  - A fast, simple and efficient ultrahigh-performance liquid 
      chromatography-fluorescence detection (UPLC-FLD) method for the determination of 
      residues of albendazole (ABZ) and its three metabolites, albendazole sulfone 
      (ABZ-SO(2)), albendazole sulfoxide (ABZ-SO), and albendazole-2-aminosulfone 
      (ABZ-2NH(2)-SO(2)), in pig and poultry muscle (chicken, duck and goose) was 
      established. The samples were extracted with ethyl acetate, and the extracts were 
      further subjected to cleanup by utilizing a series of liquid-liquid extraction 
      (LLE) steps. Then, extracts were purified by OASIS((R)) PRiME 
      hydrophilic-lipophilic balance (HLB) solid-phase extraction (SPE) cartridges (60 
      mg/3 mL). The target compounds were separated on an ACQUITY UPLC((R)) BEH C(18) 
      (2.1 mm x 100 mm, 1.7 mum) chromatographic column, using a mobile phase composed 
      of 31% acetonitrile and 69% aqueous solution (containing 0.2% formic acid and 
      0.05% triethylamine). The limits of detection (LODs) and limits of quantification 
      (LOQs) of the four target compounds in pig and poultry muscle were 0.2-3.8 microg/kg 
      and 1.0-10.9 microg/kg, respectively. The recoveries were all above 80.37% when the 
      muscle samples were spiked with the four target compounds at the LOQ, 0.5 maximum 
      residue limit (MRL), 1.0 MRL, and 2.0 MRL levels. The intraday relative standard 
      deviations (RSDs) were less than 5.11%, and the interday RSDs were less than 
      6.29%.
FAU - He, Zhaoyuan
AU  - He Z
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Diao, Zhixiang
AU  - Diao Z
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Guo, Yawen
AU  - Guo Y
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Xie, Kaizhou
AU  - Xie K
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Chen, Lan
AU  - Chen L
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
AD  - College of Veterinary Medicine, Yangzhou University, Yangzhou 225009, China.
FAU - Xue, Chun
AU  - Xue C
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Lu, Yang
AU  - Lu Y
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Chen, Jinyuan
AU  - Chen J
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
FAU - Zhang, Tao
AU  - Zhang T
AUID- ORCID: 0000-0003-1170-1622
AD  - College of Animal Science and Technology, Yangzhou University, Yangzhou 225009, 
      China.
AD  - Joint International Research Laboratory of Agriculture & Agri-Product Safety, 
      Yangzhou University, Yangzhou 225009, China.
LA  - eng
GR  - CARS-41/the China Agriculture Research System of MOF and MARA/
GR  - PAPD/the Priority Academic Programme Development of Jiangsu Higher Education 
      Institutions/
GR  - none/the Yangzhou University High-End Talent Support Program/
PT  - Journal Article
DEP - 20211002
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC8535246
OTO - NOTNLM
OT  - albendazole (ABZ) and its three metabolites
OT  - pig muscle
OT  - poultry muscle
OT  - ultrahigh-performance liquid chromatography-fluorescence detection (UPLC-FLD)
COIS- The authors declare no conflict of interest.
EDAT- 2021/10/24 06:00
MHDA- 2021/10/24 06:01
PMCR- 2021/10/02
CRDT- 2021/10/23 01:07
PHST- 2021/08/26 00:00 [received]
PHST- 2021/09/28 00:00 [revised]
PHST- 2021/09/29 00:00 [accepted]
PHST- 2021/10/23 01:07 [entrez]
PHST- 2021/10/24 06:00 [pubmed]
PHST- 2021/10/24 06:01 [medline]
PHST- 2021/10/02 00:00 [pmc-release]
AID - foods10102350 [pii]
AID - foods-10-02350 [pii]
AID - 10.3390/foods10102350 [doi]
PST - epublish
SO  - Foods. 2021 Oct 2;10(10):2350. doi: 10.3390/foods10102350.