PMID- 34690279
OWN - NLM
STAT- MEDLINE
DCOM- 20211130
LR  - 20211130
IS  - 1531-6963 (Electronic)
IS  - 1040-8711 (Linking)
VI  - 34
IP  - 1
DP  - 2022 Jan 1
TI  - Updates in cutaneous manifestations of systemic vasculitis.
PG  - 25-32
LID - 10.1097/BOR.0000000000000847 [doi]
AB  - PURPOSE OF REVIEW: The main purpose of this review is to present newly reported 
      cutaneous manifestations of systemic vasculitis, updates in investigations to 
      verify systemic involvement in cases with cutaneous vasculitis and new 
      therapeutic guidelines. The spectrum of COVID-19-related vasculitis is also 
      covered. RECENT FINDINGS: Only a few reports highlighted new cutaneous 
      presentations or associations with some systemic vasculitic entities. For 
      example, the association of inflammatory disorders with Takayasu arteritis, the 
      importance of considering Kawasaki disease in febrile children with erythema 
      nodosum, the development of necrotic ulcers on fingers and toes in Behcet's 
      disease and the possible presence of polyarteritis nodosa-like pathological 
      features in vulvar ulcers of Behcet's disease. New attempts to classify cutaneous 
      manifestations of giant cell arteritis (GCA) and antineutrophil cytoplasmic 
      antibody-associated vasculitis (AAV) and the diagnostic investigations for 
      cutaneous vasculitis cases to verify systemic involvement are discussed. 
      Treatment of systemic vasculitis with cutaneous vasculitis should be tailored 
      according to disease status. A plethora of reports in the past 2 years focused on 
      the broad spectrum of COVID-19 vasculitic manifestations. SUMMARY: Although newly 
      reported cutaneous manifestations of systemic vasculitis are relatively uncommon, 
      the plethora of reports in the past 2 years on COVID-19 vasculitis necessitates 
      the expansion of the classification of vasculitis associated with probable cause 
      to include severe acute respiratory syndrome coronavirus-2 (SARS-Cov-2) 
      vasculitis.
CI  - Copyright (c) 2021 Wolters Kluwer Health, Inc. All rights reserved.
FAU - Elbendary, Amira
AU  - Elbendary A
AD  - Department of Dermatology, Dermatopathology Unit.
FAU - Abdel-Halim, Mona R E
AU  - Abdel-Halim MRE
AD  - Department of Dermatology, Dermatopathology Unit.
FAU - Ragab, Gaafar
AU  - Ragab G
AD  - Department of Internal Medicine, Rheumatology and Clinical Immunology Unit, 
      Faculty of Medicine, Cairo University, Cairo, Egypt.
LA  - eng
PT  - Journal Article
PT  - Review
PL  - United States
TA  - Curr Opin Rheumatol
JT  - Current opinion in rheumatology
JID - 9000851
SB  - IM
MH  - *Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
MH  - *COVID-19
MH  - Humans
MH  - SARS-CoV-2
MH  - *Skin Diseases, Vascular
MH  - *Takayasu Arteritis/complications/diagnosis
EDAT- 2021/10/26 06:00
MHDA- 2021/12/01 06:00
CRDT- 2021/10/25 06:14
PHST- 2021/10/26 06:00 [pubmed]
PHST- 2021/12/01 06:00 [medline]
PHST- 2021/10/25 06:14 [entrez]
AID - 00002281-202201000-00006 [pii]
AID - 10.1097/BOR.0000000000000847 [doi]
PST - ppublish
SO  - Curr Opin Rheumatol. 2022 Jan 1;34(1):25-32. doi: 10.1097/BOR.0000000000000847.