PMID- 34695554 OWN - NLM STAT- MEDLINE DCOM- 20220426 LR - 20220508 IS - 1097-6809 (Electronic) IS - 0741-5214 (Linking) VI - 75 IP - 5 DP - 2022 May TI - Physical and psychological functioning of patients with chronic limb ischemia during a 1-year period after endovascular revascularization. PG - 1679-1686 LID - S0741-5214(21)02338-7 [pii] LID - 10.1016/j.jvs.2021.10.021 [doi] AB - OBJECTIVE: Symptoms of peripheral artery disease (PAD) and patients' physical and psychological status are related in a vicious circle. The aim of this study was to determine the relationships between improvement in parameters of PAD after endovascular procedures and changes in patients' physical and psychological status. METHODS: We studied 140 consecutive patients with PAD: 50 patients with chronic limb-threatening ischemia (CLTI), 50 patients with intermittent claudication (IC) undergoing an endovascular procedure, and 40 patients with IC who were not qualified for leg revascularization. All participating patients were assessed at the beginning of the study and at 3 and 12 months of follow-up; scores taken included ankle-brachial index, 6-minute walking test distance, Barthel Index, activities of daily living index, instrumental activities of daily living (IADL) index, Mini-Mental State Examination, and Hospital Anxiety and Depression Scale. RESULTS: After 12 months of follow-up, an improvement in PAD-related symptoms following leg revascularization had been maintained in 56% of the patients with CLTI and in 68% of those with IC. Twelve months after endovascular leg revascularization, the scores in respect of activities of daily living, IADL, and Mini-Mental State Examination had increased, and scores for Hospital Anxiety and Depression Scale had decreased in patients with both CLTI and IC. A higher baseline score in the IADL index was associated with a reduction in the 1-year cardiovascular event risk (odds ratio, 95% confidence interval, 0.70; 0.54-0.91; P < .01). CONCLUSIONS: In patients with PAD, endovascular procedures not only improved PAD-related symptoms, but also ameliorated patients' physical state, improved cognitive function, and reduced depression. CI - Copyright (c) 2021 Society for Vascular Surgery. Published by Elsevier Inc. All rights reserved. FAU - Banas, Wioletta AU - Banas W AD - Department of Vascular and Internal Diseases, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland. FAU - Czerniak, Beata AU - Czerniak B AD - Department of Vascular and Internal Diseases, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland. FAU - Budzynski, Jacek AU - Budzynski J AD - Department of Vascular and Internal Diseases, Nicolaus Copernicus University in Torun, Ludwik Rydygier Collegium Medicum, Bydgoszcz, Poland. Electronic address: budz@cps.pl. LA - eng PT - Journal Article DEP - 20211022 PL - United States TA - J Vasc Surg JT - Journal of vascular surgery JID - 8407742 SB - IM MH - Activities of Daily Living MH - *Arterial Occlusive Diseases MH - *Endovascular Procedures/adverse effects MH - Humans MH - Intermittent Claudication/diagnosis/therapy MH - Ischemia/diagnosis/surgery MH - *Peripheral Arterial Disease/diagnosis/surgery MH - Risk Factors MH - Treatment Outcome OTO - NOTNLM OT - Endovascular procedure OT - Functional assessment OT - Peripheral artery disease OT - Physical status OT - Psychological status EDAT- 2021/10/26 06:00 MHDA- 2022/04/27 06:00 CRDT- 2021/10/25 20:13 PHST- 2021/05/21 00:00 [received] PHST- 2021/10/01 00:00 [accepted] PHST- 2021/10/26 06:00 [pubmed] PHST- 2022/04/27 06:00 [medline] PHST- 2021/10/25 20:13 [entrez] AID - S0741-5214(21)02338-7 [pii] AID - 10.1016/j.jvs.2021.10.021 [doi] PST - ppublish SO - J Vasc Surg. 2022 May;75(5):1679-1686. doi: 10.1016/j.jvs.2021.10.021. Epub 2021 Oct 22.