PMID- 34695823
OWN - NLM
STAT- MEDLINE
DCOM- 20220706
LR  - 20220928
IS  - 1423-0100 (Electronic)
IS  - 0300-5526 (Print)
IS  - 0300-5526 (Linking)
VI  - 65
IP  - 3
DP  - 2022
TI  - Molecular Detection of Parvovirus in Manchurian Chipmunks (Tamias sibiricus 
      asiaticus) Captured in Korea.
PG  - 160-166
LID - 10.1159/000520388 [doi]
AB  - Cross-species transmission of viral diseases alarms our global community for its 
      potential of novel pandemic events. Of various viral pathogens noted recently, 
      parvoviruses have posed public health threats not only to humans but also to wild 
      animals. To investigate the prevalence of parvoviruses in wild Manchurian 
      chipmunks, here we detected genetic fragments of the nonstructural protein of 
      parvovirus by polymerase chain reaction in wild Manchurian chipmunk specimens 
      captured in the central and southern regions of South Korea and compared their 
      sequence homology with references. Of a total of 348 specimens examined, chipmunk 
      parvovirus (ChpPV)-specific gene fragments were detected with a 31.32% rate (109 
      chipmunks of 348) in their kidney, liver, lung, and spleen samples, and the 
      chipmunks captured in Gangwon Province exhibited the highest positive rate 
      (45.37%), followed by Gyeongsang (35.29%), Gyeonggi (31.03%), Chungcheong 
      (20.00%), and Jeolla (19.70%). When compared with the reference sequences, a 
      partial ChpPV sequence showed 97.70% identity to the previously reported Korean 
      strain at the nucleic acid level. In the phylogenetic analysis, ChpPV exhibited 
      closer relationship to primate parvoviruses, erythroviruses, and bovine 
      parvovirus than to adeno-associated viruses. Despite limited sample size and 
      genetic sequences examined in this study, our results underline the prevalence of 
      ChpPV in Korea and emphasize the need of close surveillance of parvoviruses in 
      wild animals.
CI  - (c) 2021 The Author(s). Published by S. Karger AG, Basel.
FAU - Kim, Jin Il
AU  - Kim JI
AD  - Department of Microbiology, The Institute for Viral Diseases and Korea Bank for 
      Pathogenic Viruses, Korea University College of Medicine, Seoul, Republic of 
      Korea.
FAU - Park, Kwangsook
AU  - Park K
AD  - Department of Microbiology, The Institute for Viral Diseases and Korea Bank for 
      Pathogenic Viruses, Korea University College of Medicine, Seoul, Republic of 
      Korea.
FAU - Shin, Hyunho
AU  - Shin H
AD  - Department of Microbiology, The Institute for Viral Diseases and Korea Bank for 
      Pathogenic Viruses, Korea University College of Medicine, Seoul, Republic of 
      Korea.
FAU - Choi, Soo Min
AU  - Choi SM
AD  - Department of Microbiology, The Institute for Viral Diseases and Korea Bank for 
      Pathogenic Viruses, Korea University College of Medicine, Seoul, Republic of 
      Korea.
FAU - Song, Ki-Joon
AU  - Song KJ
AD  - Department of Microbiology, The Institute for Viral Diseases and Korea Bank for 
      Pathogenic Viruses, Korea University College of Medicine, Seoul, Republic of 
      Korea.
LA  - eng
PT  - News
DEP - 20211025
PL  - Switzerland
TA  - Intervirology
JT  - Intervirology
JID - 0364265
SB  - IM
MH  - Animals
MH  - Animals, Wild
MH  - *Parvoviridae Infections/epidemiology/veterinary
MH  - *Parvovirus/genetics
MH  - Phylogeny
MH  - Sciuridae
PMC - PMC9501794
OTO - NOTNLM
OT  - Phylogenetic analysis
OT  - Chipmunk
OT  - Molecular detection
OT  - Parvovirus
COIS- The authors have no conflicts of interest to declare.
EDAT- 2021/10/26 06:00
MHDA- 2022/07/07 06:00
PMCR- 2021/10/25
CRDT- 2021/10/25 20:28
PHST- 2021/07/06 00:00 [received]
PHST- 2021/10/18 00:00 [accepted]
PHST- 2021/10/26 06:00 [pubmed]
PHST- 2022/07/07 06:00 [medline]
PHST- 2021/10/25 20:28 [entrez]
PHST- 2021/10/25 00:00 [pmc-release]
AID - 000520388 [pii]
AID - int-0065-0160 [pii]
AID - 10.1159/000520388 [doi]
PST - ppublish
SO  - Intervirology. 2022;65(3):160-166. doi: 10.1159/000520388. Epub 2021 Oct 25.