PMID- 34703394
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211028
IS  - 1450-1147 (Print)
IS  - 1607-3312 (Electronic)
IS  - 1450-1147 (Linking)
VI  - 20
IP  - 3
DP  - 2021 Jul-Sep
TI  - Is abnormal gallbladder ejection fraction hokum? Retrospective chart review of 
      gallbladder ejection fraction and subsequent postoperative symptom relief, 
      surgical pathology, and current literature review.
PG  - 260-265
LID - 10.4103/wjnm.WJNM_117_20 [doi]
AB  - The purpose of this report is to investigate the clinical importance of increased 
      or decreased gallbladder ejection fraction (GBEF) and ultrasound findings for 
      biliary dyskinesia by evaluating postsurgical symptom relief and surgical 
      pathology. Single institution electronic medical record review was prepared for 
      patients who underwent hepatobiliary iminodiacetic acid (HIDA) scan with GBEF and 
      cholecystectomy between January 2013 and March 2020. Relevant data included 
      patient demographics, ultrasound results, surgical pathology, HIDA with GBEF 
      results, and postoperative symptom relief at the time of follow-up. Student's 
      t-test was also utilized for additional statistical analysis. A total of 67 
      patients underwent cholecystectomy within a 1-month period of time after HIDA 
      with GBEF. Of these patients, 97% had findings consistent with chronic 
      cholecystitis and 3% of the patients demonstrated both acute and chronic 
      cholecystitis surgical pathology. Fifty-seven percent of the patients 
      demonstrated a GBEF <38%, 30% had a GBEF >80%, and 13% had a GBEF 38%-80% with a 
      postoperative symptom resolution around 82%, 77%, and 100%, respectively. GBEF 
      alone may not be determinative regarding gallbladder pathology or postoperative 
      symptom relief in patients that present with typical symptoms. Regarding 
      dyskinetic gallbladders, elevated and decreased GBEF groups were not 
      significantly different in terms of surgical pathology or symptom relief. These 
      patients may benefit from being treated as a single group rather than as separate 
      entities. Elevated and decreased GBEF groups demonstrated mostly normal 
      ultrasound results that raised concern for the utility of ultrasound as a rule 
      out test for gallbladder inflammation.
CI  - Copyright: (c) 2021 World Journal of Nuclear Medicine.
FAU - Chu, Youngmin
AU  - Chu Y
AD  - Department of Radiology, State University of New York Upstate Medical University, 
      Syracuse, NY, USA.
FAU - McGrath, Mary A
AU  - McGrath MA
AD  - Department of Radiology, State University of New York Upstate Medical University, 
      Syracuse, NY, USA.
LA  - eng
PT  - Journal Article
DEP - 20210212
PL  - Germany
TA  - World J Nucl Med
JT  - World journal of nuclear medicine
JID - 101286955
PMC - PMC8488886
OTO - NOTNLM
OT  - Biliary dyskinesia
OT  - chronic cholecystitis
OT  - elevated gallbladder ejection fraction
COIS- There are no conflicts of interest.
EDAT- 2021/10/28 06:00
MHDA- 2021/10/28 06:01
PMCR- 2021/02/12
CRDT- 2021/10/27 07:06
PHST- 2020/08/13 00:00 [received]
PHST- 2020/09/21 00:00 [revised]
PHST- 2020/10/13 00:00 [accepted]
PHST- 2021/10/27 07:06 [entrez]
PHST- 2021/10/28 06:00 [pubmed]
PHST- 2021/10/28 06:01 [medline]
PHST- 2021/02/12 00:00 [pmc-release]
AID - WJNM-20-260 [pii]
AID - 10.4103/wjnm.WJNM_117_20 [doi]
PST - epublish
SO  - World J Nucl Med. 2021 Feb 12;20(3):260-265. doi: 10.4103/wjnm.WJNM_117_20. 
      eCollection 2021 Jul-Sep.