PMID- 34705111
OWN - NLM
STAT- MEDLINE
DCOM- 20220527
LR  - 20220527
IS  - 1436-2813 (Electronic)
IS  - 0941-1291 (Linking)
VI  - 52
IP  - 6
DP  - 2022 Jun
TI  - Electromagnetic navigation bronchoscopy versus virtual bronchoscopy navigation 
      for improving the diagnosis of peripheral lung lesions: analysis of the 
      predictors of successful diagnosis.
PG  - 923-930
LID - 10.1007/s00595-021-02398-z [doi]
AB  - PURPOSE: To investigate if electromagnetic navigation bronchoscopy (ENB) improves 
      the diagnostic yield for peripheral lung lesions from that achieved by virtual 
      bronchoscopy navigation (VBN). METHODS: This retrospective study compared the 
      results of 100 ENB-transbronchial lung biopsies (TBLBs) with those of 50 
      VBN-TBLBs at a single institution. RESULTS: ENB improved the diagnostic yield 
      significantly compared with VBN (64.0% for 19.4 +/- 9.0 mm tumors vs. 46.0% for 
      27.6 +/- 8.9 mm tumors; p < 0.0001). Irrespective of the bronchus sign, ENB was 
      more favorable than VBN, with 81.0% (47/58) achieved by ENB vs. 60.0% (21/35) 
      achieved by VBN in the presence of the positive bronchus sign (p = 0.0283), and 
      40.5% (17/42) achieved by ENB vs. 13.3% (2/15) achieved by VBN in the absence of 
      the bronchus sign (p = 0.0431). Univariate analysis identified tumor size 
      (p = 0.0048), amount of intravenous sedation (p = 0.0182), registration time 
      (p = 0.0111), minimum distance to target (p = 0.0244), and the bronchus sign 
      (p < 0.0001) as factors that affected the yield significantly for ENB. 
      Multivariate analysis identified the bronchus sign (odds ratio 6.74; 95% CI 
      1.84-24.7) and the registration time (OR 1.01; 95% CI 1.00-1.02) as significant 
      factors. CONCLUSIONS: Despite the bronchus sign being a significant factor, ENB 
      improved the diagnostic yield of smaller lesions significantly, compared with 
      VBN, regardless of the bronchus sign.
CI  - (c) 2021. Springer Nature Singapore Pte Ltd.
FAU - Yutaka, Yojiro
AU  - Yutaka Y
AUID- ORCID: 0000-0003-4220-969X
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan. 
      yutaka7@kuhp.kyoto-u.ac.jp.
FAU - Sato, Toshihiko
AU  - Sato T
AD  - Department of Thoracic, Breast and Pediatric Surgery, Fukuoka University, 
      Fukuoka, Japan.
FAU - Isowa, Masahide
AU  - Isowa M
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Murata, Yoshitake
AU  - Murata Y
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Tanaka, Satona
AU  - Tanaka S
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Yamada, Yoshito
AU  - Yamada Y
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Ohsumi, Akihito
AU  - Ohsumi A
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Nakajima, Daisuke
AU  - Nakajima D
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Hamaji, Masatsugu
AU  - Hamaji M
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Menju, Toshi
AU  - Menju T
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
FAU - Chen-Yoshikawa, Toyofumi Fengshi
AU  - Chen-Yoshikawa TF
AD  - Department of Thoracic Surgery, Nagoya University Hospital, Nagoya, Japan.
FAU - Date, Hiroshi
AU  - Date H
AD  - Department of Thoracic Surgery, Kyoto University Hospital, Kyoto, Japan.
LA  - eng
PT  - Journal Article
DEP - 20211027
PL  - Japan
TA  - Surg Today
JT  - Surgery today
JID - 9204360
SB  - IM
MH  - *Bronchoscopy/methods
MH  - Electromagnetic Phenomena
MH  - Humans
MH  - Lung/pathology
MH  - *Lung Neoplasms/diagnosis/pathology
MH  - Retrospective Studies
OTO - NOTNLM
OT  - Bronchus sign
OT  - Diagnostic yield
OT  - Electromagnetic navigation bronchoscopy
OT  - Peripheral lung lesion
OT  - Virtual bronchoscopy navigation
EDAT- 2021/10/28 06:00
MHDA- 2022/05/28 06:00
CRDT- 2021/10/27 12:30
PHST- 2021/05/18 00:00 [received]
PHST- 2021/09/28 00:00 [accepted]
PHST- 2021/10/28 06:00 [pubmed]
PHST- 2022/05/28 06:00 [medline]
PHST- 2021/10/27 12:30 [entrez]
AID - 10.1007/s00595-021-02398-z [pii]
AID - 10.1007/s00595-021-02398-z [doi]
PST - ppublish
SO  - Surg Today. 2022 Jun;52(6):923-930. doi: 10.1007/s00595-021-02398-z. Epub 2021 
      Oct 27.