PMID- 34708748
OWN - NLM
STAT- MEDLINE
DCOM- 20211104
LR  - 20220427
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 69
IP  - 11
DP  - 2021 Nov
TI  - Regional variation in diabetic retinopathy and associated factors in Spectrum of 
      Eye Disease in Diabetes (SPEED) study in India-Report 5.
PG  - 3095-3101
LID - 10.4103/ijo.IJO_3620_20 [doi]
AB  - PURPOSE: To study the zonal variations in diabetic retinopathy (DR) and 
      associated factors in people with known type 2 diabetes mellitus (T2DM) attending 
      large eye care facilities in different regions of India. METHODS: In this 
      cross-sectional eye-care facility-based study, India was divided into five zones; 
      large eye care facilities with a good referral base and offering an entire range 
      of care for patients with DR were invited. First-time T2DM attendees aged >/=18 
      years were recruited. All subjects received a comprehensive systemic and 
      ophthalmic examination. DR and systemic diseases were classified as per the 
      international/national standards. Findings were compared between the zones and 
      with the national average. RESULTS: Fourteen eye-care facilities (15% public) 
      from five zones participated. In the cohort of 11,173 people, there were more 
      males (59%); the average age was above 45 years, and in 57%, DM had been 
      diagnosed more than 5 years earlier. Compared with the overall study population, 
      the proportion of people with any DR, sight-threatening DR, and blind were higher 
      in the east zone (42.5%, 95% confidence interval [CI]: 40.2-44.8; 24.3%, 95% CI 
      22.3-26.3, and 11.5%, respectively); diabetic macular edema was more frequent in 
      the south zone (12.2%, 95% CI 11.2-13.2); people with moderate-to-severe visual 
      impairment were more in the west zone (32.1%) and higher proportion of people in 
      the south-central zone had systemic hypertension (56.8%, 95% CI 54.8-58.9). 
      CONCLUSION: The zonal variation in DR and related vision loss could be related to 
      variable health-seeking behavior, availability, and confidence in the available 
      services.
FAU - Das, Taraprasad
AU  - Das T
AD  - Srimati Kanuri Santhamma Centre for Vitreoretinal Diseases, L V Prasad Eye 
      Institute (Kallam Anji Reddy campus), Hyderabad, Telangana, India.
FAU - Murthy, Gudlavalleti V S
AU  - Murthy GVS
AD  - Indian Institute of Public Health, Public Health Foundation of India, Hyderabad, 
      India; London School of Hygiene & Tropical Medicine, London, UK.
FAU - Pant, Hira B
AU  - Pant HB
AD  - Indian Institute of Public Health, Public Health Foundation of India, Hyderabad, 
      India.
FAU - Gilbert, Clare
AU  - Gilbert C
AD  - London School of Hygiene & Tropical Medicine, London, UK.
FAU - Rajalakshmi, Ramachandran
AU  - Rajalakshmi R
AD  - Department of Ophthalmology, Dr. Mohan's Diabetes Specialties Centre and Madras 
      Diabetes Research Foundation, Chennai, India.
FAU - Behera, Umesh C
AU  - Behera UC
AD  - Department of Vitreo-Retina, L V Prasad Eye Institute (Mithu Tulsi Chanrai 
      campus), Bhubaneswar, India.
LA  - eng
PT  - Journal Article
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
CIN - Indian J Ophthalmol. 2021 Nov;69(11):3101-3102. PMID: 34708749
MH  - Adolescent
MH  - Adult
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - *Diabetic Retinopathy/diagnosis/epidemiology
MH  - Humans
MH  - India/epidemiology
MH  - *Macular Edema
MH  - Male
MH  - Middle Aged
MH  - Prevalence
MH  - Risk Factors
PMC - PMC8725106
OTO - NOTNLM
OT  - Diabetic macular edema
OT  - India
OT  - diabetic retinopathy
OT  - sight-threatening diabetic retinopathy
COIS- None
EDAT- 2021/10/29 06:00
MHDA- 2021/11/05 06:00
PMCR- 2021/11/01
CRDT- 2021/10/28 08:39
PHST- 2021/10/28 08:39 [entrez]
PHST- 2021/10/29 06:00 [pubmed]
PHST- 2021/11/05 06:00 [medline]
PHST- 2021/11/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2021_69_11_3095_329286 [pii]
AID - IJO-69-3095 [pii]
AID - 10.4103/ijo.IJO_3620_20 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2021 Nov;69(11):3095-3101. doi: 10.4103/ijo.IJO_3620_20.