PMID- 34708790
OWN - NLM
STAT- MEDLINE
DCOM- 20211104
LR  - 20220531
IS  - 1998-3689 (Electronic)
IS  - 0301-4738 (Print)
IS  - 0301-4738 (Linking)
VI  - 69
IP  - 11
DP  - 2021 Nov
TI  - Clinical features and surgical outcomes of complications of proliferative 
      diabetic retinopathy in young adults with type 1 diabetes mellitus versus type 2 
      diabetes mellitus - A comparative observational study.
PG  - 3289-3295
LID - 10.4103/ijo.IJO_1293_21 [doi]
AB  - PURPOSE: To evaluate the clinical profile, visual outcomes, and complications 
      among young adult patients with type 1 diabetes mellitus (insulin-dependent 
      DM-T1DM) in comparison with patients with type 2 diabetes mellitus (T2DM) 
      undergoing vitrectomy for complications of proliferative diabetic retinopathy 
      (PDR).. METHODS: A retrospective review of patients between 18 and 45 years with 
      T1DM undergoing vitrectomy for complications of PDR between June 2017 and June 
      2019, with a minimum follow-up of 12 months. Consecutive patients between 30 and 
      45 years with type 2 diabetes (non-insulin-dependent DM-T2DM) who underwent 
      vitrectomy for the same indications were retrospectively enrolled as the control 
      group. RESULTS: There were 42 eyes (28 patients) in the T1DM group and 58 eyes 
      (47 patients) in the T2DM group. The average age at operation was 35.9 +/- 6.88 
      years and 39.8 +/- 3.03 years, respectively (P < 0.001). At the end of follow-up, 
      the mean logarithm of the minimum angle of resolution (logMAR) best-corrected 
      visual acuity (BCVA) improved from 1.53 +/- 0.55 to 1.30 +/- 0.93 (P value 0.07) in 
      the T1DM group and from 1.59 +/- 0.46 to 1.00 +/- 0.78 in the T2DM group (P = 
      0.0001). The rate of the primary and final reattachment was 76.2% and 88.1% in 
      the T1DM group and 84.5% and 96.6% in the T2DM group. Preoperative macular 
      tractional retinal detachment (MTRD) and neovascular glaucoma (NVG) in both the 
      groups, chronic kidney disease (CKD) and lack of preoperative Pan retinal 
      photocoagulation (PRP) in the T1DM group, hypertension (HTN) and, resurgery in 
      the T2DM group, were risk factors for poor vision at the final follow-up. 
      CONCLUSION: The visual and anatomic outcomes were poorer in the T1DM patients 
      which could be due to the longer duration of diabetes with worse glycemic 
      control, associated comorbidities like CKD, and a higher incidence of MTRD.
FAU - Kumar, Karthik
AU  - Kumar K
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Baliga, Girish
AU  - Baliga G
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Babu, Naresh
AU  - Babu N
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Rajan, Renu P
AU  - Rajan RP
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Kumar, Gautam
AU  - Kumar G
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Mishra, Chitaranjan
AU  - Mishra C
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
FAU - Chitra, R
AU  - Chitra R
AD  - Department of Biostatistics, Aravind Medical Research Foundation, Madurai, Tamil 
      Nadu, India.
FAU - Ramasamy, Kim
AU  - Ramasamy K
AD  - Department of Vitreo-Retinal Services, Aravind Eye Hospital and Post Graduate 
      Institute of Ophthalmology, Madurai, Tamil Nadu, India.
LA  - eng
PT  - Journal Article
PT  - Observational Study
PL  - India
TA  - Indian J Ophthalmol
JT  - Indian journal of ophthalmology
JID - 0405376
SB  - IM
CIN - Indian J Ophthalmol. 2021 Nov;69(11):3296. PMID: 34708791
MH  - Adult
MH  - *Diabetes Mellitus, Type 1/complications
MH  - *Diabetes Mellitus, Type 2/complications
MH  - *Diabetic Retinopathy/complications/diagnosis/surgery
MH  - Humans
MH  - Middle Aged
MH  - Retrospective Studies
MH  - Treatment Outcome
MH  - Visual Acuity
MH  - Vitrectomy
PMC - PMC8725156
OTO - NOTNLM
OT  - Proliferative diabetic retinopathy
OT  - type 1 diabetes mellitus
OT  - vitrectomy
COIS- None
EDAT- 2021/10/29 06:00
MHDA- 2021/11/05 06:00
PMCR- 2021/11/01
CRDT- 2021/10/28 08:39
PHST- 2021/10/28 08:39 [entrez]
PHST- 2021/10/29 06:00 [pubmed]
PHST- 2021/11/05 06:00 [medline]
PHST- 2021/11/01 00:00 [pmc-release]
AID - IndianJOphthalmol_2021_69_11_3289_329232 [pii]
AID - IJO-69-3289 [pii]
AID - 10.4103/ijo.IJO_1293_21 [doi]
PST - ppublish
SO  - Indian J Ophthalmol. 2021 Nov;69(11):3289-3295. doi: 10.4103/ijo.IJO_1293_21.