PMID- 34714180
OWN - NLM
STAT- MEDLINE
DCOM- 20230410
LR  - 20230410
IS  - 2169-5202 (Electronic)
IS  - 1550-0594 (Linking)
VI  - 54
IP  - 3
DP  - 2023 May
TI  - Frequency and Types of Complications Encountered in Patients With Nonconvulsive 
      Status Epilepticus in the Neurological ICU: Impact on Outcome.
PG  - 265-272
LID - 10.1177/15500594211046722 [doi]
AB  - Objectives. The frequency and types of complications in patients with 
      nonconvulsive status epilepticus (NCSE) who are followed up in the intensive care 
      unit (ICU), and the impact of these complications on outcome are not well-known. 
      We investigated the complications and their effects on prognosis in NCSE 
      patients. Methods. After reviewing the video-EEG monitoring (VEEGM) reports of 
      all the consecutive patients who were followed up in our ICU between 2009 and 
      2019, we identified two groups of patients: 1-patients with NCSE (study group) 
      and 2-patients who underwent VEEGM for possible NCSE but did not have ictal 
      recordings (no-NCSE group). Electronic health records were reviewed to identify 
      demographic and clinical data, duration of ICU care, medical and surgical 
      complications, pharmacologic treatment, and outcome. These parameters were 
      compared statistically between the groups. We also investigated the parameters 
      affecting prognosis at discharge. Results. Thirty-two patients with NCSE 
      comprised the study group. Infection developed in 84%. More than half were 
      intubated, had tracheostomy or percutaneous endoscopic gastrostomy application. 
      Refractory NCSE was associated with significantly more frequent complications and 
      worse outcome. There was a higher tendency of infections in the study group 
      (P = .059). Higher organ failure scores and prolonged stay in ICU predicted worse 
      outcome (P < .05). Conclusion. The frequency of complications in patients with 
      NCSE who are cared for in the ICU is considerable. Most of the complications are 
      similar to the other patients in ICU, except for the higher frequency of 
      infections. Increased physician awareness about modifiable parameters and timely 
      interventions might help improve prognosis.
FAU - Dericioglu, Nese
AU  - Dericioglu N
AUID- ORCID: 0000-0003-2465-3017
AD  - 64005Hacettepe University, Ankara, Turkey.
FAU - Ayvacioglu Cagan, Cansu
AU  - Ayvacioglu Cagan C
AD  - 64005Hacettepe University, Ankara, Turkey.
FAU - Sokmen, Okan
AU  - Sokmen O
AD  - 64005Hacettepe University, Ankara, Turkey.
FAU - Arsava, Ethem Murat
AU  - Arsava EM
AD  - 64005Hacettepe University, Ankara, Turkey.
FAU - Topcuoglu, Mehmet Akif
AU  - Topcuoglu MA
AD  - 64005Hacettepe University, Ankara, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20211029
PL  - United States
TA  - Clin EEG Neurosci
JT  - Clinical EEG and neuroscience
JID - 101213033
SB  - IM
MH  - Humans
MH  - *Electroencephalography/methods
MH  - *Status Epilepticus/drug therapy
MH  - Intensive Care Units
MH  - Prognosis
MH  - Patient Discharge
MH  - Retrospective Studies
OTO - NOTNLM
OT  - complication
OT  - neurological intensive care unit
OT  - nonconvulsive status epilepticus
OT  - outcome
OT  - video-EEG monitoring
EDAT- 2021/10/30 06:00
MHDA- 2023/04/10 10:16
CRDT- 2021/10/29 12:17
PHST- 2023/04/10 10:16 [medline]
PHST- 2021/10/30 06:00 [pubmed]
PHST- 2021/10/29 12:17 [entrez]
AID - 10.1177/15500594211046722 [doi]
PST - ppublish
SO  - Clin EEG Neurosci. 2023 May;54(3):265-272. doi: 10.1177/15500594211046722. Epub 
      2021 Oct 29.