PMID- 34716511
OWN - NLM
STAT- MEDLINE
DCOM- 20220405
LR  - 20220812
IS  - 1437-2320 (Electronic)
IS  - 0344-5607 (Print)
IS  - 0344-5607 (Linking)
VI  - 45
IP  - 2
DP  - 2022 Apr
TI  - The truths behind the statistics of surgical treatment for hypertensive brainstem 
      hemorrhage in China: a review.
PG  - 1195-1204
LID - 10.1007/s10143-021-01683-2 [doi]
AB  - Hypertensive brainstem hemorrhage (HBSH) is of high morbidity and mortality rate. 
      But many clinical studies were written in Chinese and had not been reviewed. A 
      systemic review of Chinese clinical studies for HBSH was performed. A systemic 
      literature search in PubMed, Web of Science, China National Knowledge 
      Infrastructure, and Weipu database and Wanfang database up to March 2020 was 
      performed. Clinical control studies including a surgical evacuation (SE) group 
      and a conservative management (CM) group were included. The clinical outcome and 
      mortality rate were compared. Ten cohort studies were included, involving 944 
      participants (304 in the SE group and 640 in the CM group). All included patients 
      were comatose, with the average age ranged from 45 to 65 years old. Among five 
      studies using mRS or GOS as outcome score, a total of 16.6% (89/535) of patients 
      achieve self-maintenance with minor disabilities, including 26.8% (34/127) in the 
      SE group and 13.5% (55/408) in the CM group. The overall mortality rate in the SE 
      group was 27.6%, ranged from 9.3 to 60% among different studies. The overall 
      mortality rate in the CM group was 60.6%, ranged from 18.5 to 100.0%. Elder and 
      comatose HBSH patients are not contraindicated for surgery. The review showed 
      that this group of patients obtained a better outcome and lower mortality rate 
      after surgical treatment. The quality of included studies was relatively low, but 
      a high-level clinical study on HBSH is of great difficulty, as both clinicians 
      and patients faced various sociological issues rather than pure medical problems.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Zheng, Wen-Jian
AU  - Zheng WJ
AD  - Department of Pediatric Neurosurgery, Beijing Tiantan Hospital, Capital Medical 
      University, Beijing, 100070, China.
FAU - Shi, Shang-Wen
AU  - Shi SW
AD  - Department of Neonatology, Zhongshan City People's Hospital, Zhongshan, 528403, 
      China.
FAU - Gong, Jian
AU  - Gong J
AUID- ORCID: 0000-0003-3224-9997
AD  - Department of Pediatric Neurosurgery, Beijing Tiantan Hospital, Capital Medical 
      University, Beijing, 100070, China. gongjian88@tom.com.
AD  - Department of Pediatric Neurosurgery, Beijing Tiantan Hospital, Capital Medical 
      University, Beijing, 100070, China. gongjian88@tom.com.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20211029
PL  - Germany
TA  - Neurosurg Rev
JT  - Neurosurgical review
JID - 7908181
SB  - IM
MH  - Aged
MH  - *Brain Stem/surgery
MH  - *Cerebral Hemorrhage/surgery
MH  - China
MH  - Cohort Studies
MH  - Humans
MH  - Middle Aged
MH  - Treatment Outcome
PMC - PMC8555712
OTO - NOTNLM
OT  - Brainstem hemorrhage
OT  - Mortality rate
OT  - Outcome
OT  - Surgery
COIS- The authors declare no competing interests.
EDAT- 2021/10/31 06:00
MHDA- 2022/04/06 06:00
PMCR- 2021/10/29
CRDT- 2021/10/30 06:05
PHST- 2021/08/17 00:00 [received]
PHST- 2021/10/25 00:00 [accepted]
PHST- 2021/10/22 00:00 [revised]
PHST- 2021/10/31 06:00 [pubmed]
PHST- 2022/04/06 06:00 [medline]
PHST- 2021/10/30 06:05 [entrez]
PHST- 2021/10/29 00:00 [pmc-release]
AID - 10.1007/s10143-021-01683-2 [pii]
AID - 1683 [pii]
AID - 10.1007/s10143-021-01683-2 [doi]
PST - ppublish
SO  - Neurosurg Rev. 2022 Apr;45(2):1195-1204. doi: 10.1007/s10143-021-01683-2. Epub 
      2021 Oct 29.