PMID- 34719994
OWN - NLM
STAT- MEDLINE
DCOM- 20220502
LR  - 20220502
IS  - 1552-4175 (Electronic)
IS  - 1099-8004 (Linking)
VI  - 24
IP  - 2
DP  - 2022 Apr
TI  - Effect of Exercise Training on Spexin Level, Appetite, Lipid Accumulation 
      Product, Visceral Adiposity Index, and Body Composition in Adults With Type 2 
      Diabetes.
PG  - 152-162
LID - 10.1177/10998004211050596 [doi]
AB  - ObjectiveTo compare the effects of resistance and aerobic training (RT and AT) on 
      spexin (SPX), appetite, lipid accumulation product (LAP), visceral adiposity 
      index (VAI), and body composition in type 2 diabetes mellitus (T2DM) patients. 
      Materials and Methods: Thirty-six T2DM men were randomized to receive RT (n = 
      12), AT (n = 12), or to act as a non-exercise control (CON, n = 12) 3 days a week 
      for 12 weeks. Results: SPX was increased after both RT and AT (66.2% and 46.5%, 
      respectively). VAI, LAP, and homeostasis model assessment-insulin resistance 
      (HOMA-IR) were reduced in both groups, while quantitative insulin sensitivity 
      check index (Quicki) and McAuley's indexes were increased following both 
      interventions. However, the increases of both hunger and PFC in the RT group were 
      greater than those of the AT. Moreover, the improvement of upper-body strength 
      (41% vs. 10.3%) and lower-body strength (42.2% vs. 20.5%) in the RT group was 
      greater than those of the AT. Conclusion: Our investigation shows that regardless 
      of the modes of the regimen, a 12-week exercise intervention with RT and AT can 
      effectively induce a significant improvement in SPX levels, appetite, LAP, VAI, 
      and body composition in adults with T2DM.
FAU - Mohammadi, Arash
AU  - Mohammadi A
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, 48440Ferdowsi 
      University of Mashhad, Mashhad, Iran.
FAU - Bijeh, Nahid
AU  - Bijeh N
AUID- ORCID: 0000-0001-7039-3549
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, 48440Ferdowsi 
      University of Mashhad, Mashhad, Iran.
FAU - Moazzami, Mahtab
AU  - Moazzami M
AD  - Department of Exercise Physiology, Faculty of Sport Sciences, 48440Ferdowsi 
      University of Mashhad, Mashhad, Iran.
FAU - Kazem Khodaei
AU  - Kazem Khodaei
AD  - Department of Sport Physiology and Corrective Exercise, Faculty of Sport 
      Sciences, 117045Urmia University, Urmia, Iran.
FAU - Rahimi, Najmeh
AU  - Rahimi N
AD  - Department of Internal Medicine, Vasei Hospital, 56941Sabzevar University of 
      Medical Sciences, Sabzevar, Iran.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
DEP - 20211031
PL  - United States
TA  - Biol Res Nurs
JT  - Biological research for nursing
JID - 9815758
SB  - IM
MH  - Adiposity
MH  - Adult
MH  - Appetite
MH  - Body Composition
MH  - Body Mass Index
MH  - *Diabetes Mellitus, Type 2/therapy
MH  - Exercise
MH  - Humans
MH  - *Insulin Resistance
MH  - *Lipid Accumulation Product
MH  - Male
OTO - NOTNLM
OT  - exercise training
OT  - lipid accumulation product
OT  - spexin
OT  - type 2 diabetes
OT  - visceral adiposity index
EDAT- 2021/11/02 06:00
MHDA- 2022/05/03 06:00
CRDT- 2021/11/01 08:43
PHST- 2021/11/02 06:00 [pubmed]
PHST- 2022/05/03 06:00 [medline]
PHST- 2021/11/01 08:43 [entrez]
AID - 10.1177/10998004211050596 [doi]
PST - ppublish
SO  - Biol Res Nurs. 2022 Apr;24(2):152-162. doi: 10.1177/10998004211050596. Epub 2021 
      Oct 31.