PMID- 34722401 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220427 IS - 2251-7200 (Print) IS - 2251-7200 (Electronic) IS - 2251-7200 (Linking) VI - 11 IP - 5 DP - 2021 Oct TI - Investigation of Eye Lens Dose Estimate based on AAPM Report 293 in Head Computed Tomography. PG - 563-572 LID - 10.31661/jbpe.v0i0.2104-1304 [doi] AB - BACKGROUND: Estimation of eye lens dose is important in head computed tomography (CT) examination since the eye lens is a sensitive organ to ionizing radiation. OBJECTIVE: The purpose of this study is to compare estimations of eye lens dose in head CT examinations using local size-specific dose estimate (SSDE) based on size-conversion factors of the American Association of Physicists in Medicine (AAPM) Report No. 293 with those based on size-conversion factors of the AAPM Report No. 220. MATERIAL AND METHODS: This experimental study is conducted on a group of patients who had undergone nasopharyngeal CT examination. Due to the longitudinal (z-axis) dose fluctuation, the average global SSDE and average local SSDE (i.e. particular slices where the eyes are located) were investigated. All estimates were compared to the measurement results using thermo-luminescent dosimeters (TLDs). The estimated and measured doses were implemented for 14 patients undergoing nasopharyngeal CT examination. RESULTS: It was found that the percentage differences of the volume CT dose index (CTDI(vol)), average global SSDE based on AAPM No. 220 (SSDE(o,g)), average local SSDE based on AAPM No. 220 (SSDE(o,l)), average global SSDE based on AAPM No. 293 (SSDE(n,g)) and average local SSDE based on AAPM No. 293 (SSDE(n,l)) against the measured TLD doses were 22.5, 21.7, 15.0, 9.3, and 2.1%, respectively. All comparisons between dose estimates and TLD measurements gave p-values less than 0.001, except for SSDE(n,l) (p-value = 0.566). CONCLUSION: SSDE based on AAPM Report No. 293 can be used to accurately estimate eye lens radiation doses by performing the calculations on a number of specific slices containing the eyes. CI - Copyright: (c) Journal of Biomedical Physics and Engineering. FAU - Anam, Choirul AU - Anam C AD - PhD, Department of Physics, Faculty of Sciences and Mathematics, Diponegoro University, Jl. Prof. Soedarto SH, Semarang 50275, Central Java, Indonesia. FAU - Kusuma Dewi, Winda AU - Kusuma Dewi W AD - MSc, Department of Physics, Faculty of Sciences and Mathematics, Diponegoro University, Jl. Prof. Soedarto SH, Semarang 50275, Central Java, Indonesia. FAU - Masdi, Masdi AU - Masdi M AD - BSc, Department of Radiology, Prof. Margono Hospital, Purwokerto, Indonesia. FAU - Haryanto, Freddy AU - Haryanto F AD - PhD, Department of Physics, Faculty of Mathematics and Natural Sciences, Institut Teknologi Bandung Jl. Ganesha 10 Bandung 40132, Indonesia. FAU - Fujibuchi, Toshioh AU - Fujibuchi T AD - PhD, Department of Health Sciences, Faculty of Medical Sciences, Kyushu University, 3-1-1 Maidashi, Higashi-ku, Fukuoka 812-8582, Japan. FAU - Dougherty, Geoff AU - Dougherty G AD - PhD, Department of Applied Physics and Medical Imaging, California State University Channel Islands, Camarillo, CA 93012, USA. LA - eng PT - Journal Article DEP - 20211001 PL - Iran TA - J Biomed Phys Eng JT - Journal of biomedical physics & engineering JID - 101589641 PMC - PMC8546161 OTO - NOTNLM OT - Algorithms OT - Computed Tomography OT - Eye Lens Dose OT - Ionizing OT - Organ Dose OT - Radiation OT - Size-Specific Dose Estimates OT - X-Rays EDAT- 2021/11/02 06:00 MHDA- 2021/11/02 06:01 PMCR- 2021/10/01 CRDT- 2021/11/01 09:25 PHST- 2021/04/09 00:00 [received] PHST- 2021/06/22 00:00 [accepted] PHST- 2021/11/01 09:25 [entrez] PHST- 2021/11/02 06:00 [pubmed] PHST- 2021/11/02 06:01 [medline] PHST- 2021/10/01 00:00 [pmc-release] AID - JBPE-11-5 [pii] AID - 10.31661/jbpe.v0i0.2104-1304 [doi] PST - epublish SO - J Biomed Phys Eng. 2021 Oct 1;11(5):563-572. doi: 10.31661/jbpe.v0i0.2104-1304. eCollection 2021 Oct.