PMID- 34723983 OWN - NLM STAT- MEDLINE DCOM- 20220105 LR - 20220105 IS - 1935-2735 (Electronic) IS - 1935-2727 (Print) IS - 1935-2727 (Linking) VI - 15 IP - 11 DP - 2021 Nov TI - Nudge strategies for behavior-based prevention and control of neglected tropical diseases: A scoping review and ethical assessment. PG - e0009239 LID - 10.1371/journal.pntd.0009239 [doi] LID - e0009239 AB - BACKGROUND: Nudging, a strategy that uses subtle stimuli to direct people's behavior, has recently been included as an effective and low-cost behavior change strategy in low- and middle- income countries (LMIC), targeting behavior-based prevention and control of neglected tropical diseases (NTDs). The present scoping review aims to provide a timely overview of how nudge interventions have been applied within this field. In addition, the review proposes a framework for the ethical consideration of nudges for NTD prevention and control, or more broadly global health promotion. METHODS: A comprehensive search was performed in several databases: MEDLINE, PsycINFO, and Embase (Ovid), Web of Science Core Collection, CINAHL, ERIC and Econ.Lit (EBSCO), as well as registered trials and reviews in CENTRAL and PROSPERO to identify ongoing or unpublished studies. Additionally, studies were included through a handpicked search on websites of governmental nudge units and global health or development organizations. RESULTS: This scoping review identified 33 relevant studies, with only two studies targeting NTDs in particular, resulting in a total of 67 nudge strategies. Most nudges targeted handwashing behavior and were focused on general health practices rather than targeting a specific disease. The most common nudge strategies were those targeting decision assistance, such as facilitating commitment and reminder actions. The majority of nudges were of moderate to high ethical standards, with the highest standards being those that had the most immediate and significant health benefits, and those implemented by agents in a trust relationship with the target audience. CONCLUSION: Three key recommendations should inform research investigating nudge strategies in global health promotion in general. Firstly, future efforts should investigate the different opportunities that nudges present for targeting NTDs in particular, rather than relying solely on integrated health promotion approaches. Secondly, to apply robust study designs including rigorous process and impact evaluation which allow for a better understanding of 'what works' and 'how it works'. Finally, to consider the ethical implications of implementing nudge strategies, specifically in LMIC. FAU - Vande Velde, Fiona AU - Vande Velde F AUID- ORCID: 0000-0002-9979-1935 AD - Department of Public Health Science, Faculty of Landscape and Society, Norwegian University of Life Sciences, As, Norway. FAU - Overgaard, Hans J AU - Overgaard HJ AUID- ORCID: 0000-0001-7604-3785 AD - Faculty of Science and Technology, Norwegian University of Life Sciences, As, Norway. AD - Department of Microbiology, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand. FAU - Bastien, Sheri AU - Bastien S AUID- ORCID: 0000-0002-4351-5704 AD - Department of Public Health Science, Faculty of Landscape and Society, Norwegian University of Life Sciences, As, Norway. AD - Department of Community Health Sciences, Cumming School of Medicine, University of Calgary, Calgary, Canada. AD - The Centre for Evidence-Based Public Health: A JBI Affiliated Group, Department of Public Health Science, NMBU, As, Norway. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20211101 PL - United States TA - PLoS Negl Trop Dis JT - PLoS neglected tropical diseases JID - 101291488 SB - IM MH - *Health Behavior/ethics MH - Health Promotion/ethics MH - Humans MH - Neglected Diseases/*prevention & control/psychology MH - Tropical Medicine/*ethics PMC - PMC8584752 COIS- The authors have declared that no competing interests exist. EDAT- 2021/11/02 06:00 MHDA- 2022/01/06 06:00 PMCR- 2021/11/01 CRDT- 2021/11/01 16:46 PHST- 2021/02/16 00:00 [received] PHST- 2021/10/13 00:00 [accepted] PHST- 2021/11/11 00:00 [revised] PHST- 2021/11/02 06:00 [pubmed] PHST- 2022/01/06 06:00 [medline] PHST- 2021/11/01 16:46 [entrez] PHST- 2021/11/01 00:00 [pmc-release] AID - PNTD-D-21-00223 [pii] AID - 10.1371/journal.pntd.0009239 [doi] PST - epublish SO - PLoS Negl Trop Dis. 2021 Nov 1;15(11):e0009239. doi: 10.1371/journal.pntd.0009239. eCollection 2021 Nov.