PMID- 34727049 OWN - NLM STAT- MEDLINE DCOM- 20211222 LR - 20211222 IS - 1943-5681 (Electronic) IS - 0002-9645 (Linking) VI - 83 IP - 1 DP - 2021 Nov 1 TI - Comparison of image quality of corneal and retinal optical coherence tomography using sedation and general anesthesia protocols with or without retrobulbar anesthesia in horses. PG - 72-79 LID - ajvr.21.02.0029 [pii] LID - 10.2460/ajvr.21.02.0029 [doi] AB - OBJECTIVE: To compare image quality and acquisition time of corneal and retinal spectral domain optical coherence tomography (SD-OCT) under 3 different sedation-anesthesia conditions in horses. ANIMALS: 6 middle-aged geldings free of ocular disease. PROCEDURES: 1 randomly selected eye of each horse was evaluated via SD-OCT under the following 3 conditions: standing sedation without retrobulbar anesthetic block (RB), standing sedation with RB, and general anesthesia with RB. Five regions of interest were evaluated in the cornea (axial and 12, 3, 6, and 9 o'clock positions) and fundus (optic nerve head). Three diagnostic scans of predetermined quality were obtained per anatomical region. Image acquisition times and total scans per site were recorded. Corneal and retinal SD-OCT image quality was graded on a subjective scale from 0 (nondiagnostic) to 4 (excellent). RESULTS: Mean values for the standing sedation without RB, standing sedation with RB, and general anesthesia conditions were 24, 23, and 17, respectively, for total cornea scan attempts; 23, 19, and 19 for total retina-scan attempts; 14.6, 13.2, and 9.2 minutes for total cornea scan time; 19.1, 9.2, and 13.0 for total retina scan time; 2.0, 2.3, and 2.5 for cornea grade; and 2.7, 2.9, and 2.5 for retina grade. CONCLUSIONS AND CLINICAL RELEVANCE: The RB facilitated globe akinesia and improved the percentage of scans in frame and region of interest accuracy for retinal imaging via OCT in horses. Retrobulbar blocks improved clinical image acquisition while minimizing motion artifact. FAU - Hefner, Ethan M AU - Hefner EM FAU - Lin, Hui-Chu AU - Lin HC FAU - Cole, Robert C AU - Cole RC FAU - Moore, Phillip A AU - Moore PA FAU - McMullen, Richard J AU - McMullen RJ LA - eng PT - Journal Article DEP - 20211101 PL - United States TA - Am J Vet Res JT - American journal of veterinary research JID - 0375011 SB - IM MH - *Anesthesia, General/veterinary MH - Animals MH - Cornea/diagnostic imaging MH - Horses MH - Retina/diagnostic imaging MH - *Tomography, Optical Coherence/veterinary EDAT- 2021/11/03 06:00 MHDA- 2021/12/24 06:00 CRDT- 2021/11/02 17:17 PHST- 2021/11/03 06:00 [pubmed] PHST- 2021/12/24 06:00 [medline] PHST- 2021/11/02 17:17 [entrez] AID - ajvr.21.02.0029 [pii] AID - 10.2460/ajvr.21.02.0029 [doi] PST - epublish SO - Am J Vet Res. 2021 Nov 1;83(1):72-79. doi: 10.2460/ajvr.21.02.0029.