PMID- 34729199 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211105 IS - 2053-8855 (Print) IS - 2053-8855 (Electronic) IS - 2053-8855 (Linking) VI - 2021 IP - 10 DP - 2021 Oct TI - Concomitant acute pulmonary embolism, myocardial infarction and ischemic stroke due to paradoxical embolism from a patent foramen ovale: a case report. PG - omab101 LID - 10.1093/omcr/omab101 [doi] LID - omab101 AB - A patent foramen ovale (PFO) is a cause of paradoxical embolism. Although most patients with a PFO are asymptomatic, various clinical manifestations may be associated with PFO. The most important is a cryptogenic stroke. Concomitant acute pulmonary embolism (APE), acute myocardial infarction (AMI) and acute ischemic stroke (AIS) due to paradoxical embolism from a PFO are extremely rare. We describe a 77-year-old woman with a past medical history of hypertension who was transferred due to a sudden onset of dyspnea followed by cardiopulmonary arrest. Based on the patient's medical history, transthoracic and transesophageal echocardiography, coronary angiography, and a whole-body contrasted computed tomography, we diagnosed concomitant APE, AMI and AIS caused by a paradoxical embolism from a PFO. Appropriate knowledge of the pathophysiology of this rare critical illness is important for prompt diagnosis and treatment. CI - (c) The Author(s) 2021. Published by Oxford University Press. FAU - Takemoto, Kiyoshi AU - Takemoto K AUID- ORCID: 0000-0001-8072-6298 AD - Division of Critical Care Medicine, Nara Prefecture General Medical Center, Nara City, Nara, 6308581, Japan. FAU - Nakamura, Michitaka AU - Nakamura M AD - Division of Critical Care Medicine, Nara Prefecture General Medical Center, Nara City, Nara, 6308581, Japan. FAU - Atagi, Kazuaki AU - Atagi K AD - Division of Critical Care Medicine, Nara Prefecture General Medical Center, Nara City, Nara, 6308581, Japan. LA - eng PT - Case Reports DEP - 20211026 PL - England TA - Oxf Med Case Reports JT - Oxford medical case reports JID - 101642070 PMC - PMC8557459 EDAT- 2021/11/04 06:00 MHDA- 2021/11/04 06:01 PMCR- 2021/10/26 CRDT- 2021/11/03 06:57 PHST- 2021/06/07 00:00 [received] PHST- 2021/07/22 00:00 [revised] PHST- 2021/09/23 00:00 [accepted] PHST- 2021/11/03 06:57 [entrez] PHST- 2021/11/04 06:00 [pubmed] PHST- 2021/11/04 06:01 [medline] PHST- 2021/10/26 00:00 [pmc-release] AID - omab101 [pii] AID - 10.1093/omcr/omab101 [doi] PST - epublish SO - Oxf Med Case Reports. 2021 Oct 26;2021(10):omab101. doi: 10.1093/omcr/omab101. eCollection 2021 Oct.