PMID- 34735449
OWN - NLM
STAT- MEDLINE
DCOM- 20211222
LR  - 20211222
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 16
IP  - 11
DP  - 2021
TI  - Dynamics of task-induced modulation of spontaneous brain activity and functional 
      connectivity in the triple resting-state networks assessed using the visual 
      oddball paradigm.
PG  - e0246709
LID - 10.1371/journal.pone.0246709 [doi]
LID - e0246709
AB  - The default mode network (DMN), the salience network (SN), and the central 
      executive network (CEN) are considered as the core resting-state brain networks 
      (RSN) due to their involvement in a wide range of cognitive tasks. Despite the 
      large body of knowledge related to their regional spontaneous activity (RSA) and 
      functional connectivity (FC) of these networks, less is known about the dynamics 
      of the task-associated modulation on these parameters and the task-induced 
      interaction between these three networks. We have investigated the effects of the 
      visual-oddball paradigm on three fMRI measures (amplitude of low-frequency 
      fluctuations for RSA, regional homogeneity for local FC, and degree centrality 
      for global FC) in these three core RSN. A rest-task-rest paradigm was used and 
      the RSNs were identified using independent component analysis (ICA) on the 
      resting-state data. The observed patterns of change differed noticeably between 
      the networks and were tightly associated with the task-related brain activity and 
      the distinct involvement of the networks in the performance of the single 
      subtasks. Furthermore, the inter-network analysis showed an increased 
      synchronization of CEN with the DMN and the SN immediately after the task, but 
      not between the DMN and SN. Higher pre-task inter-network synchronization between 
      the DMN and the CEN was associated with shorter reaction times and thus better 
      performance. Our results provide some additional insights into the dynamics 
      within and between the triple RSN. Further investigations are required in order 
      to understand better their functional importance and interplay.
FAU - Sbaihat, Hasan
AU  - Sbaihat H
AUID- ORCID: 0000-0003-4973-3195
AD  - Institute of Neuroscience and Medicine, INM-4, Forschungszentrum Julich GmbH, 
      Julich, Germany.
AD  - Department of Medical Imaging, Arab-American University Palestine, AAUP, Jenin, 
      Palestine.
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen 
      University, Aachen, Germany.
FAU - Rajkumar, Ravichandran
AU  - Rajkumar R
AUID- ORCID: 0000-0001-5875-5316
AD  - Institute of Neuroscience and Medicine, INM-4, Forschungszentrum Julich GmbH, 
      Julich, Germany.
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen 
      University, Aachen, Germany.
AD  - JARA-BRAIN-Translational Medicine, Aachen, Germany.
FAU - Ramkiran, Shukti
AU  - Ramkiran S
AD  - Institute of Neuroscience and Medicine, INM-4, Forschungszentrum Julich GmbH, 
      Julich, Germany.
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen 
      University, Aachen, Germany.
AD  - JARA-BRAIN-Translational Medicine, Aachen, Germany.
FAU - Assi, Abed Al-Nasser
AU  - Assi AA
AD  - Department of Medical Imaging, Arab-American University Palestine, AAUP, Jenin, 
      Palestine.
FAU - Shah, N Jon
AU  - Shah NJ
AD  - Institute of Neuroscience and Medicine, INM-4, Forschungszentrum Julich GmbH, 
      Julich, Germany.
AD  - JARA-BRAIN-Translational Medicine, Aachen, Germany.
AD  - Department of Neurology, RWTH Aachen University, Aachen, Germany.
AD  - Institute of Neuroscience and Medicine, INM-11, Forschungszentrum Julich GmbH, 
      Julich, Germany.
FAU - Veselinovic, Tanja
AU  - Veselinovic T
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen 
      University, Aachen, Germany.
FAU - Neuner, Irene
AU  - Neuner I
AD  - Institute of Neuroscience and Medicine, INM-4, Forschungszentrum Julich GmbH, 
      Julich, Germany.
AD  - Department of Psychiatry, Psychotherapy and Psychosomatics, RWTH Aachen 
      University, Aachen, Germany.
AD  - JARA-BRAIN-Translational Medicine, Aachen, Germany.
LA  - eng
PT  - Clinical Trial
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20211104
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Adult
MH  - *Cerebral Cortex/diagnostic imaging/physiology
MH  - Cognition/*physiology
MH  - *Connectome
MH  - Female
MH  - Humans
MH  - *Magnetic Resonance Imaging
MH  - Male
MH  - *Neural Pathways/diagnostic imaging/physiology
PMC - PMC8568109
COIS- The authors have declared that no competing interests exist.
EDAT- 2021/11/05 06:00
MHDA- 2021/12/24 06:00
PMCR- 2021/11/04
CRDT- 2021/11/04 17:25
PHST- 2021/01/22 00:00 [received]
PHST- 2021/10/16 00:00 [accepted]
PHST- 2021/11/04 17:25 [entrez]
PHST- 2021/11/05 06:00 [pubmed]
PHST- 2021/12/24 06:00 [medline]
PHST- 2021/11/04 00:00 [pmc-release]
AID - PONE-D-21-01149 [pii]
AID - 10.1371/journal.pone.0246709 [doi]
PST - epublish
SO  - PLoS One. 2021 Nov 4;16(11):e0246709. doi: 10.1371/journal.pone.0246709. 
      eCollection 2021.