PMID- 34736933
OWN - NLM
STAT- MEDLINE
DCOM- 20220414
LR  - 20220414
IS  - 1097-6779 (Electronic)
IS  - 0016-5107 (Linking)
VI  - 95
IP  - 4
DP  - 2022 Apr
TI  - Comparison of endoscopic full-thickness resection and cap-assisted endoscopic 
      full-thickness resection in the treatment of small (</=1.5 cm) gastric GI stromal 
      tumors.
PG  - 660-670.e2
LID - S0016-5107(21)01763-6 [pii]
LID - 10.1016/j.gie.2021.10.026 [doi]
AB  - BACKGROUND AND AIMS: With the increasing incidence of small GI stromal tumors 
      (GISTs), endoscopic full-thickness resection (EFTR) and cap-assisted EFTR 
      (EFTR-C) have been suggested as 2 effective resection methods. We aimed to 
      compare the outcomes of EFTR and EFTR-C for the treatment of small (</=1.5 cm) 
      gastric GISTs. METHODS: This retrospective study included 67 patients who 
      underwent EFTR and 46 patients who underwent EFTR-C at Nanjing Drum Tower 
      Hospital. Clinicopathologic features, adverse events (AEs), and outcomes were 
      compared between the 2 groups. Univariate and multivariate linear and logistic 
      regressions were used to analyze the effects of the procedure on the therapeutic 
      outcomes of patients and adjusted for covariates in the multivariate analysis. 
      RESULTS: The tumor size in the EFTR group tended to be larger (P = .005). The 
      resection time in the EFTR-C group was shorter than that in the EFTR group (38.3 
      +/- 20.7 minutes vs 15.0 +/- 11.8 minutes, P < .001), which retained statistical 
      significance with adjustment for the covariates (adjusted mean difference, 22.2; 
      95% confidence interval, 15.0-29.4; P < .001). The R0 resection rate of the EFTR 
      group was 94.0% and of the EFTR-C group 97.8% (P = .355). The EFTR-C group was 
      superior to the EFTR group in terms of perioperative therapeutic outcomes, AEs, 
      and postoperative recovery. No recurrence occurred in the EFTR and EFTR-C groups. 
      CONCLUSIONS: EFTR-C was found to be the preferable technique for small (</=1.5 cm) 
      gastric GISTs with shorter operation times, lower AEs, faster postoperative 
      recovery, and shorter hospitalization times as compared with EFTR.
CI  - Copyright (c) 2022 American Society for Gastrointestinal Endoscopy. All rights 
      reserved.
FAU - Yang, Jinping
AU  - Yang J
AD  - Department of Gastroenterology, Nanjing Drum Tower Hospital Clinical College of 
      Nanjing Medical University, Jiangsu, China.
FAU - Ni, Muhan
AU  - Ni M
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Jiang, Jingwei
AU  - Jiang J
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Ren, Ximei
AU  - Ren X
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Zhu, Tingting
AU  - Zhu T
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Cao, Shouli
AU  - Cao S
AD  - Department of Gastroenterology, Shandong Provincial Third Hospital, Cheeloo 
      College of Medicine, Shandong University, Shandong, China.
FAU - Hassan, Shahzeb
AU  - Hassan S
AD  - Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
FAU - Lv, Ying
AU  - Lv Y
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Zhang, Xiaoqi
AU  - Zhang X
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Wei, Yongyue
AU  - Wei Y
AD  - Department of Biostatistics, School of Public Health, Nanjing Medical University, 
      Nanjing, China.
FAU - Wang, Lei
AU  - Wang L
AD  - Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing 
      University Medical School, Jiangsu, China.
FAU - Xu, Guifang
AU  - Xu G
AD  - Department of Gastroenterology, Nanjing Drum Tower Hospital Clinical College of 
      Nanjing Medical University, Jiangsu, China; Department of Gastroenterology, The 
      Affiliated Drum Tower Hospital of Nanjing University Medical School, Jiangsu, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20211101
PL  - United States
TA  - Gastrointest Endosc
JT  - Gastrointestinal endoscopy
JID - 0010505
SB  - IM
CIN - Gastrointest Endosc. 2022 Apr;95(4):811. PMID: 35303982
MH  - *Endoscopic Mucosal Resection/methods
MH  - *Gastrointestinal Stromal Tumors/surgery
MH  - Humans
MH  - Retrospective Studies
MH  - *Stomach Neoplasms/pathology
MH  - Treatment Outcome
EDAT- 2021/11/06 06:00
MHDA- 2022/04/15 06:00
CRDT- 2021/11/05 05:47
PHST- 2021/03/17 00:00 [received]
PHST- 2021/10/24 00:00 [accepted]
PHST- 2021/11/06 06:00 [pubmed]
PHST- 2022/04/15 06:00 [medline]
PHST- 2021/11/05 05:47 [entrez]
AID - S0016-5107(21)01763-6 [pii]
AID - 10.1016/j.gie.2021.10.026 [doi]
PST - ppublish
SO  - Gastrointest Endosc. 2022 Apr;95(4):660-670.e2. doi: 10.1016/j.gie.2021.10.026. 
      Epub 2021 Nov 1.