PMID- 34744903
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211110
IS  - 1664-1078 (Print)
IS  - 1664-1078 (Electronic)
IS  - 1664-1078 (Linking)
VI  - 12
DP  - 2021
TI  - Fatigue, Social Support, and Depression in Individuals With Coronary Artery 
      Disease.
PG  - 732795
LID - 10.3389/fpsyg.2021.732795 [doi]
LID - 732795
AB  - Background: Given that approximately one-third of individuals with coronary 
      artery disease (CAD) remain severely fatigued after completion the cardiac 
      rehabilitation, it is necessary to identify reliable intervention targets aimed 
      at reducing fatigue. Perceived social support is closely linked to health 
      outcomes and depressive symptoms in individuals with CAD. However, to our 
      knowledge, the relationship between subjective fatigue levels and social support 
      in those with CAD has not been analyzed. Objective: We aimed to examine the 
      associations between perceived social support and subjective fatigue levels in 
      individuals with CAD with and without depression symptoms. Methods: This 
      cross-sectional study was comprised of 1,036 participants with CAD (57+/-9years, 
      77% men) 1-2weeks after acute coronary syndrome (ACS). Participants completed the 
      Hospital Anxiety and Depression scale (HADS), Multidimensional Fatigue 
      Inventory-20 (MFI-20), and the Multidimensional Scale of Perceived Social Support 
      (MSPSS). Results: In total, 12% (n=129) of study participants had elevated 
      depression symptoms (HADS score>/=8). In individuals with CAD and depressive 
      symptoms, after adjustment for sex, age, New York Heart Association (NYHA) 
      functional class, and anxiety, linear regression analyses showed significant 
      inverse associations between higher social support from others and general, 
      physical fatigue as well as reduced activity and motivation (p<0.001). Following 
      the same method of statistical analysis and control in non-depressed individuals 
      with CAD (88%), social support from family was inversely linked to mental fatigue 
      (p's<0.05). Similarly, social support from friends was significantly associated 
      with lower general, physical, and mental fatigue as well as reduced activity, 
      while social support from others was significantly associated with lower general 
      and mental fatigue (p's<0.001). The overall higher total support was linked with 
      reduced motivation (p<0.05) in the depressed study participants, while there was 
      lower general and mental fatigue (p<0.05) in non-depressed individuals. 
      Conclusion: The results of this study suggest that fatigue and its features could 
      be associated by the perceived social support in individuals with CAD following 
      ACSs. While in individuals with CAD and depressive symptoms, greater subjective 
      fatigue is associated with less perceived social support from others, higher 
      levels of subjective fatigue in non-depressed individuals with CAD are 
      significantly associated with reduced perceived social support from friends.
CI  - Copyright (c) 2021 Kazukauskiene, Bunevicius, Gecaite-Stonciene and Burkauskas.
FAU - Kazukauskiene, Nijole
AU  - Kazukauskiene N
AD  - Laboratory of Behavioral Medicine, Neuroscience Institute, Lithuanian University 
      of Health Sciences, Palanga, Lithuania.
FAU - Bunevicius, Adomas
AU  - Bunevicius A
AD  - Laboratory of Behavioral Medicine, Neuroscience Institute, Lithuanian University 
      of Health Sciences, Palanga, Lithuania.
FAU - Gecaite-Stonciene, Julija
AU  - Gecaite-Stonciene J
AD  - Laboratory of Behavioral Medicine, Neuroscience Institute, Lithuanian University 
      of Health Sciences, Palanga, Lithuania.
FAU - Burkauskas, Julius
AU  - Burkauskas J
AD  - Laboratory of Behavioral Medicine, Neuroscience Institute, Lithuanian University 
      of Health Sciences, Palanga, Lithuania.
LA  - eng
PT  - Journal Article
DEP - 20211020
PL  - Switzerland
TA  - Front Psychol
JT  - Frontiers in psychology
JID - 101550902
PMC - PMC8565598
OTO - NOTNLM
OT  - acute coronary sindrome
OT  - cardiac rehabilitation
OT  - coronary artery disease
OT  - depression
OT  - fatigue
OT  - social support
COIS- JG-S has served as a consultant at FACITtrans. In the past several years, JB has 
      worked as a consultant to Cogstate, Ltd. The remaining authors declare that the 
      research was conducted in the absence of any commercial or financial 
      relationships that could be construed as a potential conflict of interest.
EDAT- 2021/11/09 06:00
MHDA- 2021/11/09 06:01
PMCR- 2021/10/20
CRDT- 2021/11/08 06:35
PHST- 2021/06/29 00:00 [received]
PHST- 2021/09/28 00:00 [accepted]
PHST- 2021/11/08 06:35 [entrez]
PHST- 2021/11/09 06:00 [pubmed]
PHST- 2021/11/09 06:01 [medline]
PHST- 2021/10/20 00:00 [pmc-release]
AID - 10.3389/fpsyg.2021.732795 [doi]
PST - epublish
SO  - Front Psychol. 2021 Oct 20;12:732795. doi: 10.3389/fpsyg.2021.732795. eCollection 
      2021.