PMID- 34749586
OWN - NLM
STAT- MEDLINE
DCOM- 20221215
LR  - 20221222
IS  - 1532-5040 (Electronic)
IS  - 0959-3985 (Linking)
VI  - 39
IP  - 1
DP  - 2023 Jan
TI  - Impact of resistance training on muscle fatigue in type 2 diabetes mellitus 
      patients during dynamic fatigue protocol.
PG  - 26-38
LID - 10.1080/09593985.2021.2001882 [doi]
AB  - BACKGROUND: Type 2 diabetes mellitus (T2DM) is often accompanied with several 
      neuromuscular complications of which muscle fatigue is one of the scantily 
      studied and less-explored complication of this disease. OBJECTIVE: To investigate 
      the effects of resistance training (RT) on muscle fatigue markers from 
      electromyography (EMG) and capillary blood in T2DM patients. METHODS: Forty T2DM 
      patients were randomized to either RT (n = 20) or control group (n = 20). They 
      were assessed for EMG indices of muscle fatigue along with blood lactate (at 
      three time points: Lactate(pre), Lactate(peak), Lactate(post)) during a dynamic 
      fatigue protocol. Dynamic fatigue protocol consisted of 5 sets of leg press 
      exercise at 10 repetition maximum intensity. RT group performed moderate 
      intensity (65%-75% 1 repetition maximum) RT 3 times/week for 12 weeks. Control 
      group followed usual routine. RESULTS: Findings revealed that EMG amplitude (root 
      mean square) and Dimitrov's muscle fatigue index (FI(nsmk)) decreased 
      significantly while median frequency (MF) increased significantly during the 
      dynamic fatigue protocol for both vastus medialis (Root mean square, p = .02; 
      FI(nsmk), p = .001; MF, p < .001) and vastus lateralis muscle (Root mean square, 
      p= .04,FI(nsmk,)p = .01; MF, p < .001) post-RT. Blood lactate responses did not 
      change after RT (Lactate(pre), p = .55; Lactate(peak), p = .91; Lactate(post), p 
      = .33). CONCLUSIONS: Findings of the present study illustrated that moderate 
      intensity RT led to a significant reduction muscle fatigue in knee extensor 
      muscles of T2DM patients. These results reinforce the utilization of RT in 
      patients with T2DM.
FAU - Bhati, Pooja
AU  - Bhati P
AD  - Faculty of Allied Health Sciences, Shree Guru Gobind Singh Tricentenary 
      University, Gurugram, Haryana, 122505, India.
FAU - Hussain, M Ejaz
AU  - Hussain ME
AD  - Faculty of Physiotherapy and Allied Health Sciences, Shree Guru Gobind Singh 
      Tricentenary University, Chandu-Budhera, Gurugram, India.
LA  - eng
PT  - Clinical Trial Protocol
PT  - Journal Article
DEP - 20211108
PL  - England
TA  - Physiother Theory Pract
JT  - Physiotherapy theory and practice
JID - 9015520
RN  - 0 (Lactates)
SB  - IM
MH  - Humans
MH  - Muscle Fatigue/physiology
MH  - *Resistance Training/methods
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Electromyography/methods
MH  - Muscle, Skeletal/physiology
MH  - Quadriceps Muscle/physiology
MH  - Lactates
MH  - Randomized Controlled Trials as Topic
OTO - NOTNLM
OT  - Exercise
OT  - diabetes
OT  - fatigue
OT  - muscle
OT  - strength
EDAT- 2021/11/10 06:00
MHDA- 2022/12/16 06:00
CRDT- 2021/11/09 05:33
PHST- 2021/11/10 06:00 [pubmed]
PHST- 2022/12/16 06:00 [medline]
PHST- 2021/11/09 05:33 [entrez]
AID - 10.1080/09593985.2021.2001882 [doi]
PST - ppublish
SO  - Physiother Theory Pract. 2023 Jan;39(1):26-38. doi: 
      10.1080/09593985.2021.2001882. Epub 2021 Nov 8.