PMID- 34765438
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220714
IS  - 2213-0489 (Print)
IS  - 2213-0489 (Electronic)
IS  - 2213-0489 (Linking)
VI  - 16
DP  - 2021
TI  - Successful allogeneic bone marrow transplantation after massive gastrointestinal 
      bleeding in a patient with myelodysplastic syndrome associated with intestinal 
      Behcet-like disease.
PG  - 100278
LID - 10.1016/j.lrr.2021.100278 [doi]
LID - 100278
AB  - A 45-year-old woman was diagnosed with myelodysplastic syndrome (MDS) with 
      trisomy 8 and Behcet-like disease (BLD) with multiple colorectal ulcers. 
      Nonspecific inflammatory cells were infiltrated in the intestinal mucosa, whereas 
      fluorescence in situ hybridization (FISH) analysis revealed only sporadic trisomy 
      8-positive cells. She presented massive lower gastrointestinal bleeding early 
      after bone marrow transplantation but achieved long-term remission of both MDS 
      and BLD. This is the first report of massive gastrointestinal bleeding after 
      transplantation for MDS with BLD. Based on FISH analysis, dysregulation of 
      systemic inflammation may be involved in BLD rather than direct invasion by 
      trisomy 8-positive MDS clones.
CI  - (c) 2021 The Authors.
FAU - Ishii, Arata
AU  - Ishii A
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Tsukamoto, Shokichi
AU  - Tsukamoto S
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Mishina, Tatsuzo
AU  - Mishina T
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Izumi, Shintaro
AU  - Izumi S
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Nagai, Yurie
AU  - Nagai Y
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Yamazaki, Miki
AU  - Yamazaki M
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Hino, Yutaro
AU  - Hino Y
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Kayamori, Kensuke
AU  - Kayamori K
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Oshima-Hasegawa, Nagisa
AU  - Oshima-Hasegawa N
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Muto, Tomoya
AU  - Muto T
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Mitsukawa, Shio
AU  - Mitsukawa S
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, 
      Chiba, Japan.
FAU - Takeda, Yusuke
AU  - Takeda Y
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
FAU - Mimura, Naoya
AU  - Mimura N
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Department of Transfusion Medicine and Cell Therapy, Chiba University Hospital, 
      Chiba, Japan.
FAU - Ohwada, Chikako
AU  - Ohwada C
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
AD  - Department of Hematology, International University of Health and Welfare School 
      of Medicine, Narita, Japan.
FAU - Nakaseko, Chiaki
AU  - Nakaseko C
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
AD  - Department of Hematology, International University of Health and Welfare School 
      of Medicine, Narita, Japan.
FAU - Ikeda, Jun-Ichiro
AU  - Ikeda JI
AD  - Department of Pathology, Chiba University Hospital, Chiba, Japan.
FAU - Sakaida, Emiko
AU  - Sakaida E
AD  - Department of Hematology, Chiba University Hospital, Chiba, Japan.
AD  - Blood and Marrow Transplant Center, Chiba University Hospital, Chiba, Japan.
LA  - eng
PT  - Case Reports
DEP - 20211029
PL  - England
TA  - Leuk Res Rep
JT  - Leukemia research reports
JID - 101608906
EIN - Leuk Res Rep. 2022 Apr 06;17:100309. PMID: 35832056
PMC - PMC8572864
OTO - NOTNLM
OT  - Behcet-like disease
OT  - Bone marrow transplantation
OT  - Gastrointestinal bleeding
OT  - Myelodysplastic syndrome
OT  - Trisomy 8
COIS- The authors declare no competing financial interests.
EDAT- 2021/11/13 06:00
MHDA- 2021/11/13 06:01
PMCR- 2021/10/29
CRDT- 2021/11/12 07:06
PHST- 2021/08/10 00:00 [received]
PHST- 2021/10/21 00:00 [revised]
PHST- 2021/10/25 00:00 [accepted]
PHST- 2021/11/12 07:06 [entrez]
PHST- 2021/11/13 06:00 [pubmed]
PHST- 2021/11/13 06:01 [medline]
PHST- 2021/10/29 00:00 [pmc-release]
AID - S2213-0489(21)00045-5 [pii]
AID - 100278 [pii]
AID - 10.1016/j.lrr.2021.100278 [doi]
PST - epublish
SO  - Leuk Res Rep. 2021 Oct 29;16:100278. doi: 10.1016/j.lrr.2021.100278. eCollection 
      2021.