PMID- 34775528
OWN - NLM
STAT- MEDLINE
DCOM- 20220321
LR  - 20220321
IS  - 1433-2965 (Electronic)
IS  - 0937-941X (Linking)
VI  - 33
IP  - 4
DP  - 2022 Apr
TI  - Radiographic indexes in AP hip radiographs prior to total hip arthroplasty reveal 
      candidates with low BMD.
PG  - 871-879
LID - 10.1007/s00198-021-06231-8 [doi]
AB  - Using anteroposterior (AP) hip radiograph, we measured several indexes to 
      investigate the association with bone mineral density (BMD) before THA and found 
      a highly effective index to predict femoral BMD. This technique is helpful for 
      both patients and clinicians to identify potential candidates with low BMD to 
      whom DXA examination is particularly recommended. INTRODUCTION: The purpose of 
      the study is to identify patients with low bone mineral density (BMD) prior to 
      total hip arthroplasty with the help of AP hip radiographs. METHODS: Indexes on 
      AP hip radiographs and T-scores from DXA examination of the lumbar spine and the 
      affected hip were acquired from patients before THA. Indexes measured on AP hip 
      radiographs including the canal calcar ratio (CCR), canal flare index (CFI), 
      morphological cortical index (MCI), canal bone ratio (CBR), and canal bone area 
      ratio (CBAR). The relevance between indexes and the T-score of femora was 
      evaluated by correlation analysis, and the diagnostic value of indexes for 
      osteopenia was examined by receiver operating characteristic (ROC) curves. 
      RESULTS: A total of 81 patients were included. The average value of CBR-7, 
      CBR-10, and CBAR (7-10) were highly related to the T-score of femora 
      (r =  - 0.592, r =  - 0.634, and r =  - 0.631, respectively, p < 0.0001). Results 
      of the intra- and interobserver variation assessment was excellent. CBR-7, 
      CBR-10, and CBAR (7-10) were significantly different between the non-osteopenia 
      and osteopenia groups (p < 0.0001). CBR-10 had the biggest area under curve 
      (AUC), means the great diagnostic value for osteopenia in the proximal femora 
      (AUC = 0.821, cutoff value = 0.3805). CONCLUSION: The canal bone ratio at 
      10 x 10(-2) m under the level of the lesser trochanter proved to be a great 
      indicator of femoral osteopenia. Trial registration Chinese Clinical Trail 
      Registry, ChiCTR2000041016. Registered 16 December 2020-Retrospectively 
      registered, http://www.chictr.org.cn/listbycreater.aspx .
CI  - (c) 2021. International Osteoporosis Foundation and National Osteoporosis 
      Foundation.
FAU - Liu, Y
AU  - Liu Y
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China.
FAU - Ma, W-J
AU  - Ma WJ
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China.
FAU - Huang, K
AU  - Huang K
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China.
FAU - Yang, J
AU  - Yang J
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China.
FAU - Zeng, Y
AU  - Zeng Y
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China.
FAU - Shen, B
AU  - Shen B
AD  - Orthopedics Research Institute, Department of Orthopedics, National Clinical 
      Research Center for Geriatrics, West China Hospital, Sichuan University, Chengdu, 
      610041, Sichuan, China. shenbin_1971@163.com.
LA  - eng
GR  - 81974347/national natural science foundation of china/
GR  - Z20191008/national clinical research center for geriatrics, west china hospital 
      sichuan university/
PT  - Journal Article
DEP - 20211113
PL  - England
TA  - Osteoporos Int
JT  - Osteoporosis international : a journal established as result of cooperation 
      between the European Foundation for Osteoporosis and the National Osteoporosis 
      Foundation of the USA
JID - 9100105
SB  - IM
MH  - Absorptiometry, Photon
MH  - *Arthroplasty, Replacement, Hip/adverse effects
MH  - Bone Density
MH  - *Bone Diseases, Metabolic/diagnostic imaging
MH  - Humans
MH  - Lumbar Vertebrae/diagnostic imaging
OTO - NOTNLM
OT  - Bone mineral density
OT  - Canal bone ratio
OT  - DXA
OT  - Hip radiography
OT  - Osteopenia
OT  - Total hip arthroplasty
EDAT- 2021/11/15 06:00
MHDA- 2022/03/22 06:00
CRDT- 2021/11/14 21:14
PHST- 2021/07/25 00:00 [received]
PHST- 2021/11/01 00:00 [accepted]
PHST- 2021/11/15 06:00 [pubmed]
PHST- 2022/03/22 06:00 [medline]
PHST- 2021/11/14 21:14 [entrez]
AID - 10.1007/s00198-021-06231-8 [pii]
AID - 10.1007/s00198-021-06231-8 [doi]
PST - ppublish
SO  - Osteoporos Int. 2022 Apr;33(4):871-879. doi: 10.1007/s00198-021-06231-8. Epub 
      2021 Nov 13.