PMID- 34776925
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20211117
IS  - 1663-4365 (Print)
IS  - 1663-4365 (Electronic)
IS  - 1663-4365 (Linking)
VI  - 13
DP  - 2021
TI  - Dance Intervention Impact on Brain Plasticity: A Randomized 6-Month fMRI Study in 
      Non-expert Older Adults.
PG  - 724064
LID - 10.3389/fnagi.2021.724064 [doi]
LID - 724064
AB  - Background: Dance is a complex activity combining physical exercise with 
      cognitive, social, and artistic stimulation. Objectives: We aimed to assess the 
      effects of dance intervention (DI) on intra and inter-network resting-state 
      functional connectivity (rs-FC) and its association to cognitive changes in a 
      group of non-demented elderly participants. Methods: Participants were randomly 
      assigned into two groups: DI and life as usual (LAU). Six-month-long DI consisted 
      of supervised 60 min lessons three times per week. Resting-state fMRI data were 
      processed using independent component analysis to evaluate the intra and 
      inter-network connectivity of large-scale brain networks. Interaction between 
      group (DI, LAU) and visit (baseline, follow-up) was assessed using ANOVA, and 
      DI-induced changes in rs-FC were correlated with cognitive outcomes. Results: 
      Data were analyzed in 68 participants (DI; n = 36 and LAU; n = 32). A significant 
      behavioral effect was found in the attention domain, with Z scores increasing in 
      the DI group and decreasing in the LAU group (p = 0.017). The DI as compared to 
      LAU led to a significant rs-FC increase of the default mode network (DMN) and 
      specific inter-network pairings, including insulo-opercular and right 
      frontoparietal/frontoparietal control networks (p = 0.019 and p = 0.023), visual 
      and language/DMN networks (p = 0.012 and p = 0.015), and cerebellar and 
      visual/language networks (p = 0.015 and p = 0.003). The crosstalk of the 
      insulo-opercular and right frontoparietal networks were associated with 
      attention/executive domain Z-scores (R = 0.401, p = 0.015, and R = 0.412, p = 
      0.012). Conclusion: The DI led to intervention-specific complex brain plasticity 
      changes that were of cognitive relevance.
CI  - Copyright (c) 2021 Balazova, Marecek, Novakova, Nemcova-Elfmarkova, Kropacova, 
      Brabenec, Grmela, Vaculikova, Svobodova and Rektorova.
FAU - Balazova, Zuzana
AU  - Balazova Z
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
AD  - Faculty of Medicine, Masaryk University, Brno, Czechia.
FAU - Marecek, Radek
AU  - Marecek R
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
AD  - First Department of Neurology, Faculty of Medicine, St. Anne's University 
      Hospital, Masaryk University, Brno, Czechia.
FAU - Novakova, L'ubomira
AU  - Novakova L
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
FAU - Nemcova-Elfmarkova, Nela
AU  - Nemcova-Elfmarkova N
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
FAU - Kropacova, Sylvie
AU  - Kropacova S
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
FAU - Brabenec, Lubos
AU  - Brabenec L
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
FAU - Grmela, Roman
AU  - Grmela R
AD  - Department of Health Promotion, Faculty of Sports Studies, Masaryk University, 
      Brno, Czechia.
FAU - Vaculikova, Pavlina
AU  - Vaculikova P
AD  - Department of Gymnastics and Combatives, Faculty of Sports Studies, Masaryk 
      University, Brno, Czechia.
FAU - Svobodova, Lenka
AU  - Svobodova L
AD  - Department of Gymnastics and Combatives, Faculty of Sports Studies, Masaryk 
      University, Brno, Czechia.
FAU - Rektorova, Irena
AU  - Rektorova I
AD  - Brain and Mind Research, Central European Institute of Technology, Masaryk 
      University, Brno, Czechia.
AD  - First Department of Neurology, Faculty of Medicine, St. Anne's University 
      Hospital, Masaryk University, Brno, Czechia.
LA  - eng
PT  - Journal Article
DEP - 20211027
PL  - Switzerland
TA  - Front Aging Neurosci
JT  - Frontiers in aging neuroscience
JID - 101525824
PMC - PMC8579817
OTO - NOTNLM
OT  - attention
OT  - cognitive
OT  - dance intervention
OT  - independent component analysis
OT  - intra-network connectivity
OT  - resting state fMRI
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2021/11/16 06:00
MHDA- 2021/11/16 06:01
PMCR- 2021/01/01
CRDT- 2021/11/15 06:56
PHST- 2021/06/11 00:00 [received]
PHST- 2021/09/28 00:00 [accepted]
PHST- 2021/11/15 06:56 [entrez]
PHST- 2021/11/16 06:00 [pubmed]
PHST- 2021/11/16 06:01 [medline]
PHST- 2021/01/01 00:00 [pmc-release]
AID - 10.3389/fnagi.2021.724064 [doi]
PST - epublish
SO  - Front Aging Neurosci. 2021 Oct 27;13:724064. doi: 10.3389/fnagi.2021.724064. 
      eCollection 2021.