PMID- 34780324 OWN - NLM STAT- MEDLINE DCOM- 20220328 LR - 20220401 IS - 1525-8955 (Electronic) IS - 0885-3010 (Linking) VI - 69 IP - 2 DP - 2022 Feb TI - Multiperspective Bistatic Ultrasound Imaging and Elastography of the Ex Vivo Abdominal Aorta. PG - 604-616 LID - 10.1109/TUFFC.2021.3128227 [doi] AB - Knowledge of aneurysm geometry and local mechanical wall parameters using ultrasound (US) can contribute to a better prediction of rupture risk in abdominal aortic aneurysms (AAAs). However, aortic strain imaging using conventional US is limited by the lateral lumen-wall contrast and resolution. In this study, ultrafast multiperspective bistatic (MP BS) imaging is used to improve aortic US, in which two curved array transducers receive simultaneously on each transmit event. The advantage of such bistatic US imaging on both image quality and strain estimations was investigated by comparing it to single-perspective monostatic (SP MS) and MP monostatic (MP MS) imaging, i.e., alternately transmitting and receiving with either transducer. Experimental strain imaging was performed in US simulations and in an experimental study on porcine aortas. Different compounding strategies were tested to retrieve the most useful information from each received US signal. Finally, apart from the conventional sector grid in curved array US imaging, a polar grid with respect to the vessel's local coordinate system is introduced. This new reconstruction method demonstrated improved displacement estimations in aortic US. The US simulations showed increased strain estimation accuracy using MP BS imaging bistatic imaging compared to MP MS imaging, with a decrease in the average relative error between 41% and 84% in vessel wall regions between transducers. In the experimental results, the mean image contrast-to-noise ratio was improved by up to 8 dB in the vessel wall regions between transducers. This resulted in an increased mean elastographic signal-to-noise ratio by about 15 dB in radial strain and 6 dB in circumferential strain. FAU - van Hal, Vera H J AU - van Hal VHJ FAU - De Hoop, Hein AU - De Hoop H FAU - Muller, Jan-Willem AU - Muller JW FAU - van Sambeek, Marc R H M AU - van Sambeek MRHM FAU - Schwab, Hans-Martin AU - Schwab HM FAU - Lopata, Richard G P AU - Lopata RGP LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220127 PL - United States TA - IEEE Trans Ultrason Ferroelectr Freq Control JT - IEEE transactions on ultrasonics, ferroelectrics, and frequency control JID - 9882735 SB - IM MH - Animals MH - Aorta, Abdominal/diagnostic imaging MH - *Aortic Aneurysm, Abdominal/diagnostic imaging MH - *Elasticity Imaging Techniques/methods MH - Stress, Mechanical MH - Swine MH - Ultrasonography EDAT- 2021/11/16 06:00 MHDA- 2022/03/29 06:00 CRDT- 2021/11/15 17:16 PHST- 2021/11/16 06:00 [pubmed] PHST- 2022/03/29 06:00 [medline] PHST- 2021/11/15 17:16 [entrez] AID - 10.1109/TUFFC.2021.3128227 [doi] PST - ppublish SO - IEEE Trans Ultrason Ferroelectr Freq Control. 2022 Feb;69(2):604-616. doi: 10.1109/TUFFC.2021.3128227. Epub 2022 Jan 27.