PMID- 34782531
OWN - NLM
STAT- MEDLINE
DCOM- 20211122
LR  - 20220115
IS  - 0971-5916 (Print)
IS  - 0975-9174 (Electronic)
IS  - 0971-5916 (Linking)
VI  - 154
IP  - 1
DP  - 2021 Jul
TI  - Risk of type 2 diabetes mellitus after gestational diabetes mellitus: A 
      systematic review & meta-analysis.
PG  - 62-77
LID - 10.4103/ijmr.IJMR_852_18 [doi]
AB  - BACKGROUND &OBJECTIVES: Women with gestational diabetes are at an increased risk 
      of being diagnosed as type 2 diabetes, but the postpartum screening rate is low. 
      To provide evidence-based data for health providers and promote postpartum 
      screening, this systematic review and meta-analysis was conducted to access the 
      risks of type 2 diabetes mellitus (T2DM) diagnosis after gestational diabetes 
      mellitus (GDM) in different demographic and maternal subgroups. METHODS: MEDLINE, 
      Embase and Cochrane Library were searched systematically. Unadjusted relative 
      risks (RRs) and 95 per cent confidence intervals (CIs) were calculated and pooled 
      using a random-effects model. Heterogeneity was assessed with Cochrane's Q text 
      and by calculating I(2) values. Subgroup analyses were conducted to address the 
      disparities of type 2 diabetes conversion after gestational diabetes in different 
      demographic and maternal subgroups. RESULTS: 1809 publications were screened and 
      39 cohort studies including 2,847,596 women were selected. In these studies, 
      78,893 women were diagnosed as T2DM at six weeks or later after delivery. The 
      unadjusted RRs of women diagnosed T2DM at six weeks or later after delivery 
      ranged from 1.32 (95% CI, 0.46-3.37) to 47.25 (95% CI, 2.95-758.01) with a pooled 
      unadjusted RR of 8.92 (95% CI, 7.84-10.14). Older women, women with a family 
      history of diabetes, Black and non-Hispanic White women and women living in 
      Europe and South-East Asia had a higher risk of developing T2DM after GDM. 
      INTERPRETATION & CONCLUSIONS: It is suggested that healthcare providers may focus 
      on older women with GDM and women with GDM and a family history of diabetes. 
      Black and non-Hispanic White women with GDM may receive more attention, and 
      healthcare providers, especially those in Europe and South-East Asia, may pay 
      more attention to preventive measures for postpartum T2DM.
FAU - You, Huaxuan
AU  - You H
AD  - Key Laboratory of Birth Defects & Related Diseases of Women & Children, Ministry 
      of Education; Department of Gynecology and Obstetrics, West China Second 
      University Hospital, Sichuan University, Chengdu, China.
FAU - Hu, Juan
AU  - Hu J
AD  - Key Laboratory of Birth Defects & Related Diseases of Women & Children, Ministry 
      of Education; Department of Emergency, West China Second University Hospital, 
      Sichuan University, Chengdu, China.
FAU - Liu, Ying
AU  - Liu Y
AD  - West China Nursing School, Sichuan University, Chengdu, China.
FAU - Luo, Biru
AU  - Luo B
AD  - Key Laboratory of Birth Defects & Related Diseases of Women & Children, Ministry 
      of Education; Department of Nursing, West China Second University Hospital, 
      Sichuan University, Chengdu, China.
FAU - Lei, Anjiang
AU  - Lei A
AD  - Key Laboratory of Birth Defects & Related Diseases of Women & Children, Ministry 
      of Education; Department of Gynecology and Obstetrics, West China Second 
      University Hospital, Sichuan University, Chengdu, China.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
PT  - Systematic Review
PL  - India
TA  - Indian J Med Res
JT  - The Indian journal of medical research
JID - 0374701
SB  - IM
MH  - Aged
MH  - *Diabetes Mellitus, Type 2/epidemiology/etiology
MH  - *Diabetes, Gestational/epidemiology
MH  - Female
MH  - Humans
MH  - Mass Screening
MH  - Postpartum Period
MH  - Pregnancy
MH  - Risk
PMC - PMC8715678
OTO - NOTNLM
OT  - Blood glucose
OT  - OGTT screening
OT  - gestational diabetes mellitus
OT  - postpartum
OT  - type 2 diabetes mellitus
COIS- None
EDAT- 2021/11/17 06:00
MHDA- 2021/11/23 06:00
PMCR- 2021/07/01
CRDT- 2021/11/16 06:14
PHST- 2021/11/16 06:14 [entrez]
PHST- 2021/11/17 06:00 [pubmed]
PHST- 2021/11/23 06:00 [medline]
PHST- 2021/07/01 00:00 [pmc-release]
AID - IndianJMedRes_2021_154_1_62_329967 [pii]
AID - IJMR-154-62 [pii]
AID - 10.4103/ijmr.IJMR_852_18 [doi]
PST - ppublish
SO  - Indian J Med Res. 2021 Jul;154(1):62-77. doi: 10.4103/ijmr.IJMR_852_18.