PMID- 34784887 OWN - NLM STAT- MEDLINE DCOM- 20211224 LR - 20211224 IS - 1471-2393 (Electronic) IS - 1471-2393 (Linking) VI - 21 IP - 1 DP - 2021 Nov 16 TI - Postpartum septic symphysitis, a rare condition with possible long-term consequences: a cohort study with long-term follow-up. PG - 776 LID - 10.1186/s12884-021-04023-w [doi] LID - 776 AB - BACKGROUND: Postpartum septic symphysitis (PPSS) is defined as acute onset of severe pain around the symphysis, restricted movement, fever, and elevated inflammatory parameters. It is a rare but serious condition requiring urgent diagnosis and treatment. The aim of this study was to describe the incidence, symptoms, diagnosis, treatment, and long-term follow-up of PPSS. METHODS: This follow-up study included 19 out of 21 women diagnosed with PPSS from 1989 to 2017 at one tertiary care hospital in Sweden. Clinical data were retrieved from hospital records and compared to those retrieved from a regional registry. Women completed a postal questionnaire, and those who reported lumbopelvic pain (LPP) were offered a clinical examination. RESULTS: 1) PPSS was diagnosed after a normal postpartum period of 24 to 50 h by blood tests (n = 19/19), ultrasonography (n = 9 /19), computer tomography (n = 8/19) or magnetic resonance imaging (n = 16/19) Treatment included aspiration of symphyseal abscesses, i.v. antibiotics and different physiotherapeutic interventions. Women with PPSS more frequently were primiparous (n = 14/19, p = 0.001), had an instrumental delivery (n = 14/19, p = 0.003), longer time of active labour (p = 0.01) and second stage of labour (p = 0.001) than women in the regional registry. 2) Ten out of 19 (52%) women reported LPP at follow-up. These women more often suffered impaired function related to LPP (Pelvic Girdle Questionnaire, 27 versus 0, p < 0.0001), a poorer health-related quality of life (EuroQol-5 dimensions p = 0.001 and EuroQol-visual analogue scale, 65 mm versus 84 mm, p = 0.022) and higher levels of anxiety and depression (Hospital Anxiety Depression Scale (HADS) HADS-Anxiety, 7 versus 2, p = 0.010; and HADS-Depression, 1 versus 0, p = 0.028) than women with no pain. 3). Of the eight women who were clinically assessed, one had lumbar pain and seven had pelvic girdle pain (PGP). CONCLUSIONS: In the largest cohort of patients with PPSS to date, primiparas and women with instrumental vaginal delivery were overrepresented, indicating that first and complicated deliveries might be risk factors. Approximately half of the women reported PGP at follow-up, with considerable consequences affecting health-related quality of life and function decades after delivery. Prospective multicentre studies are needed to establish risk factors, long-term consequences, and adequate treatment for this rare pregnancy complication. CI - (c) 2021. The Author(s). FAU - Elden, Helen AU - Elden H AUID- ORCID: 0000-0003-0000-0476 AD - Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Box 457, 405 30, Gothenburg, Sweden. helen.elden@gu.se. AD - Region Vastra Gotaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg, Sweden. helen.elden@gu.se. AD - Region Vastra Gotaland, Sahlgrenska University Hospital, Department of Orthopedics, Gothenburg, Sweden. helen.elden@gu.se. FAU - Olsen, Monika Fagevik AU - Olsen MF AD - Department of Health and Rehabilitation/Physiotherapy, Institute of Neuroscience and Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. AD - Region Vastra Gotaland, Sahlgrenska University Hospital, Department of Occupational Therapy and Physical Therapy, Gothenburg, Sweden. FAU - Hussein, Nasrin Farah AU - Hussein NF AD - Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Box 457, 405 30, Gothenburg, Sweden. FAU - Axelsson, Lisa Wibeck AU - Axelsson LW AD - Institute of Health and Care Sciences, Sahlgrenska Academy, University of Gothenburg, Box 457, 405 30, Gothenburg, Sweden. FAU - Sengpiel, Verena AU - Sengpiel V AD - Region Vastra Gotaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg, Sweden. FAU - Ullman, Michael AU - Ullman M AD - Department of Orthopaedics, Institute of Clinical Sciences, Sahlgrenska Academy, Gothenburg University, Gothenburg, Sweden. LA - eng PT - Journal Article DEP - 20211116 PL - England TA - BMC Pregnancy Childbirth JT - BMC pregnancy and childbirth JID - 100967799 SB - IM MH - Adult MH - Cohort Studies MH - Female MH - Follow-Up Studies MH - Humans MH - Low Back Pain/etiology MH - Pelvic Girdle Pain/etiology MH - Pelvic Infection/*complications/*diagnosis/therapy MH - *Postpartum Period MH - Pregnancy MH - Pregnancy Complications, Infectious/*diagnosis/therapy MH - Pubic Symphysis/diagnostic imaging/*pathology MH - Sepsis/*complications/*diagnosis/therapy MH - Sweden/epidemiology MH - Tertiary Care Centers PMC - PMC8594151 OTO - NOTNLM OT - Lumbopelvic pain OT - Osteitis pubis OT - Osteomyelitis OT - Pelvic girdle pain OT - Postpartum septic arthritis OT - Postpartum septic symphysitis OT - Symphysitis pubic COIS- The authors declare that they have no competing interests. EDAT- 2021/11/18 06:00 MHDA- 2021/12/25 06:00 PMCR- 2021/11/16 CRDT- 2021/11/17 05:36 PHST- 2020/12/21 00:00 [received] PHST- 2021/07/27 00:00 [accepted] PHST- 2021/11/17 05:36 [entrez] PHST- 2021/11/18 06:00 [pubmed] PHST- 2021/12/25 06:00 [medline] PHST- 2021/11/16 00:00 [pmc-release] AID - 10.1186/s12884-021-04023-w [pii] AID - 4023 [pii] AID - 10.1186/s12884-021-04023-w [doi] PST - epublish SO - BMC Pregnancy Childbirth. 2021 Nov 16;21(1):776. doi: 10.1186/s12884-021-04023-w.