PMID- 34785301
OWN - NLM
STAT- MEDLINE
DCOM- 20211220
LR  - 20211220
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 182
DP  - 2021 Dec
TI  - The relationship between Dietary approaches to stop hypertension diet adherence 
      and inflammatory factors and insulin resistance in overweight and obese women: A 
      cross-sectional study.
PG  - 109128
LID - S0168-8227(21)00487-3 [pii]
LID - 10.1016/j.diabres.2021.109128 [doi]
AB  - BACKGROUND: Although there is abundant evidence for an association between 
      dietary pattern, weight, and other related factors, such as homeostatic model 
      assessment for insulin resistance (HOMA-IR) and inflammatory markers; there is 
      limited information pertaining to levels of plasminogen activator inhibitor-1 
      (PAI-1) and Monocyte Chemoattractant Protein -1 (MCP-1). Therefore, this study 
      sought to examine the association between adherence to the dietary approaches to 
      stop hypertension (DASH) diet and levels of inflammatory factors PAI-1, MCP-1, 
      and HOMA-IR. METHODS: This cross-sectional study was performed on 305 obese and 
      overweight women. The typical food intake of individuals was assessed using the 
      147 items semi-quantitative food frequency questionnaire (FFQ). Body components 
      were measured for all participants. Insulin resistance was estimated by 
      homeostasis model assessment (HOMA), and biochemical parameters were examined. 
      RESULTS: No significant relationship was observed between the DASH diet and MCP-1 
      (P-trend = 0.70), PAI-1 (P-trend = 0.92), or HOMA-IR (P-trend = 0.08) in the 
      crude model. However, there was a significant inverse relationship between the 
      DASH diet and HOMA-IR (P-trend = 0.03) after adjusting for age, BMI, and physical 
      activity. CONCLUSION: This study showed that higher adherence to DASH pattern is 
      inversely correlated with HOMA-IR in overweight and obese women.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Taheri, Akram
AU  - Taheri A
AD  - Department of Nutrition, Faculty of Medicine, Sciences and Research Branch, 
      Islamic Azad, University, Tehran, Iran.
FAU - Mirzababaei, Atieh
AU  - Mirzababaei A
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), Tehran, Iran.
FAU - Setayesh, Leila
AU  - Setayesh L
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), Tehran, Iran.
FAU - Yarizadeh, Habib
AU  - Yarizadeh H
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), Tehran, Iran.
FAU - Shiraseb, Farideh
AU  - Shiraseb F
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), Tehran, Iran.
FAU - Imani, Hossein
AU  - Imani H
AD  - Department of Clinical Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences, Iran.
FAU - C T Clark, Cain
AU  - C T Clark C
AD  - Centre for Intelligent Healthcare, Coventry University, Coventry CV1 5FB, UK.
FAU - Mirzaei, Khadijeh
AU  - Mirzaei K
AD  - Department of Community Nutrition, School of Nutritional Sciences and Dietetics, 
      Tehran University of Medical Sciences (TUMS), Tehran, Iran. Electronic address: 
      mirzaei_kh@tums.ac.ir.
LA  - eng
PT  - Journal Article
DEP - 20211114
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
SB  - IM
MH  - Cross-Sectional Studies
MH  - *Dietary Approaches To Stop Hypertension
MH  - Humans
MH  - *Insulin Resistance
MH  - Obesity
MH  - Overweight
OTO - NOTNLM
OT  - DASH
OT  - HOMA-IR
OT  - MCP-1
OT  - Obese
OT  - Overweight
OT  - PAI-1
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2021/11/18 06:00
MHDA- 2021/12/21 06:00
CRDT- 2021/11/17 05:52
PHST- 2020/11/21 00:00 [received]
PHST- 2021/10/29 00:00 [revised]
PHST- 2021/11/02 00:00 [accepted]
PHST- 2021/11/18 06:00 [pubmed]
PHST- 2021/12/21 06:00 [medline]
PHST- 2021/11/17 05:52 [entrez]
AID - S0168-8227(21)00487-3 [pii]
AID - 10.1016/j.diabres.2021.109128 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2021 Dec;182:109128. doi: 10.1016/j.diabres.2021.109128. 
      Epub 2021 Nov 14.