PMID- 3479088 OWN - NLM STAT- MEDLINE DCOM- 19871130 LR - 20221207 IS - 0003-9969 (Print) IS - 0003-9969 (Linking) VI - 32 IP - 7 DP - 1987 TI - Changes in glucose metabolism in submandibular salivary glands of rats after isoproterenol or incisor-tooth amputation. PG - 499-503 AB - Rats were injected daily with isoproterenol (2 mg/kg of body wt) for up to five days, or their incisor teeth were amputated on every other day for up to five amputations. The animals were subdivided in two subgroups killed 12 or 24 h after the first or last intervention. At 12 h all enzymes except hexokinase (HK) and pyruvate kinase (PFK) showed decreased activities after isoproterenol. After incisor amputation, only increased HK and PFK activities were observed. With both procedures, there is activation of beta-adrenergic receptors but results show that different biochemical events take place, suggesting different mechanisms. FAU - Ferreira, F D AU - Ferreira FD AD - Department of Biochemistry, University of Sao Paulo, Brazil. FAU - Nicolau, J AU - Nicolau J LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't PL - England TA - Arch Oral Biol JT - Archives of oral biology JID - 0116711 RN - EC 2.7.1.1 (Hexokinase) RN - EC 2.7.1.40 (Pyruvate Kinase) RN - IY9XDZ35W2 (Glucose) RN - L628TT009W (Isoproterenol) SB - IM MH - Amputation, Surgical MH - Animals MH - Glucose/*metabolism MH - Hexokinase/metabolism MH - Incisor/surgery MH - Isoproterenol/pharmacokinetics MH - Male MH - Pyruvate Kinase/metabolism MH - Rats MH - Rats, Inbred Strains MH - Salivary Gland Diseases/*metabolism MH - Submandibular Gland/drug effects/*metabolism EDAT- 1987/01/01 00:00 MHDA- 1987/01/01 00:01 CRDT- 1987/01/01 00:00 PHST- 1987/01/01 00:00 [pubmed] PHST- 1987/01/01 00:01 [medline] PHST- 1987/01/01 00:00 [entrez] AID - 10.1016/s0003-9969(87)80011-0 [doi] PST - ppublish SO - Arch Oral Biol. 1987;32(7):499-503. doi: 10.1016/s0003-9969(87)80011-0.