PMID- 34796901
OWN - NLM
STAT- MEDLINE
DCOM- 20220221
LR  - 20220221
IS  - 1477-9145 (Electronic)
IS  - 0022-0949 (Linking)
VI  - 224
IP  - 24
DP  - 2021 Dec 15
TI  - Seasonal cellular stress phenomena and phenotypic plasticity in land snail Helix 
      lucorum populations from different altitudes.
LID - jeb243298 [pii]
LID - 10.1242/jeb.243298 [doi]
AB  - Temperature, a major abiotic environmental factor, regulates various 
      physiological functions in land snails and therefore determines their 
      biogeographical distribution. Thus, species with different distributions may 
      present different thermal tolerance limits. Additionally, the intense 
      reactivation of snail metabolic rate upon arousal from hibernation or estivation 
      may provoke stress. Land snails, Helix lucorum, display a wide altitudinal 
      distribution resulting in populations being exposed to different seasonal 
      temperature variations. The aim of the present study was to investigate the 
      expression of heat shock proteins (Hsps), mitogen activated protein kinases 
      (MAPKs) and proteins that are related to apoptosis (Bcl-2, ubiquitin), that have 
      'cytoprotective' roles and are also considered to be reliable indicators of 
      stress because of their crucial role in maintaining cellular homeostasis. These 
      proteins were assessed in H. lucorum individuals from two different populations, 
      one at Axios (sea level, 0 m) and the other at Kokkinopilos (Olympus, 1250 m), as 
      well as after mutual population exchanges, in order to find out whether the 
      different responses of these stress-related proteins depend solely on the 
      environmental temperature. The results showed seasonally altered levels in all 
      studied proteins in the hepatopancreas and foot of snails, both among different 
      populations and between the same populations exposed to varying altitudes. 
      However, individuals of the same population in their native habitat or 
      acclimatized to a different habitat showed a relatively similar pattern of 
      expression, supporting the induction of the specific proteins according to the 
      life history of each species.
CI  - (c) 2021. Published by The Company of Biologists Ltd.
FAU - Staikou, Alexandra
AU  - Staikou A
AD  - Laboratory of Zoology, Department of Zoology, School of Biology, Aristotle 
      University of Thessaloniki, GR-54124 Thessaloniki, Greece.
FAU - Feidantsis, Konstantinos
AU  - Feidantsis K
AD  - Laboratory of Animal Physiology, Department of Zoology, School of Biology, 
      Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
FAU - Gkanatsiou, Ourania
AU  - Gkanatsiou O
AD  - Laboratory of Animal Physiology, Department of Zoology, School of Biology, 
      Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
FAU - Bibos, Modestos Nakos
AU  - Bibos MN
AD  - Laboratory of Animal Physiology, Department of Zoology, School of Biology, 
      Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
FAU - Hatziioannou, Marianthi
AU  - Hatziioannou M
AD  - Department of Ichthyology and Aquatic Environment, Faculty of Agricultural 
      Sciences, University of Thessaly, Fytoko street, GR-38445 Volos, Greece.
FAU - Storey, Kenneth B
AU  - Storey KB
AD  - Institute of Biochemistry, Carleton University, 1125 Colonel By Drive, Ottawa, 
      ON, Canada, K1S 5B6.
FAU - Michaelidis, Basile
AU  - Michaelidis B
AUID- ORCID: 0000-0002-2312-6883
AD  - Laboratory of Animal Physiology, Department of Zoology, School of Biology, 
      Aristotle University of Thessaloniki, GR-54124 Thessaloniki, Greece.
LA  - eng
PT  - Journal Article
DEP - 20211214
PL  - England
TA  - J Exp Biol
JT  - The Journal of experimental biology
JID - 0243705
SB  - IM
MH  - *Adaptation, Physiological
MH  - *Altitude
MH  - Animals
MH  - Estivation
MH  - Helix, Snails/physiology
MH  - Humans
MH  - Seasons
OTO - NOTNLM
OT  - Oxidative stress
OT  - Species distribution
OT  - Temperature variation
OT  - Tissue-specific response
OT  - Vertical distribution
COIS- Competing interests The authors declare no competing or financial interests.
EDAT- 2021/11/20 06:00
MHDA- 2022/02/22 06:00
CRDT- 2021/11/19 08:46
PHST- 2021/08/04 00:00 [received]
PHST- 2021/11/15 00:00 [accepted]
PHST- 2021/11/20 06:00 [pubmed]
PHST- 2022/02/22 06:00 [medline]
PHST- 2021/11/19 08:46 [entrez]
AID - 273728 [pii]
AID - 10.1242/jeb.243298 [doi]
PST - ppublish
SO  - J Exp Biol. 2021 Dec 15;224(24):jeb243298. doi: 10.1242/jeb.243298. Epub 2021 Dec 
      14.