PMID- 34801009
OWN - NLM
STAT- MEDLINE
DCOM- 20211206
LR  - 20240404
IS  - 1471-2458 (Electronic)
IS  - 1471-2458 (Linking)
VI  - 21
IP  - 1
DP  - 2021 Nov 20
TI  - Preventing opioid use among justice-involved youth as they transition to 
      adulthood: leveraging safe adults (LeSA).
PG  - 2133
LID - 10.1186/s12889-021-12127-3 [doi]
LID - 2133
AB  - BACKGROUND: Juvenile justice (JJ) youth are at high risk of opioid and other 
      substance use (SU), dysfunctional family/social relationships, and complex 
      trauma. The purpose of the Leveraging Safe Adults (LeSA) Project is to examine 
      the effectiveness of Trust-Based Relational Intervention(R) (TBRI(R); leveraging 
      family systems by providing emotional and instrumental guidance, support, and 
      role modeling) in preventing opioid and other SU among youth after release from 
      secure residential facilities. METHODS: An effectiveness-implementation Hybrid 
      Type 1 design is used to test the effectiveness of TBRI for preventing 
      non-medical use of opioids among JJ-youth (delayed-start at the site level; a 
      randomized controlled trial at participant level) and to gain insight into 
      facility-level barriers to TBRI implementation as part of JJ re-entry protocols. 
      Recruitment includes two samples (effectiveness: 360 youth/caregiver dyads; 
      implementation: 203 JJ staff) from nine sites in two states over 3 years. 
      Participant eligibility includes 15 to 18-year-olds disposed to community 
      supervision and receiving care in a secure JJ facility, without active suicide 
      risk, and with one caregiver willing to participate. Effectiveness data come from 
      (1) youth and caregiver self-report on background, SU, psychosocial functioning, 
      and youth-caregiver relationships (Months 0, 3, 6, 12, and 18), youth monthly 
      post-release check-ins, and caregiver report on youth psychological/behavioral 
      symptoms, and (2) JJ facility records (e.g., recidivism, treatment utilization). 
      Fidelity assessment includes post-session checklists and measures of TBRI 
      strategy use. Collected four times over four years, implementation data include 
      (1) JJ staff self-report on facility and staff characteristics, use of 
      trauma-informed care and TBRI strategies, and (2) focus groups (line staff, 
      leadership separately) on use of trauma-informed strategies, uptake of new 
      interventions, and penetration, sustainment, and expansion of TBRI practices. 
      DISCUSSION: The LeSA study is testing TBRI as a means to empower caregivers to 
      help prevent opioid use and other SU among JJ-youth. TBRI's multiple components 
      offer an opportunity for caregivers to supplement and extend gains during 
      residential care. If effective and implemented successfully, the LeSA protocol 
      will help expand the application of TBRI with a wider audience and provide 
      guidance for implementing multi-component interventions in complex systems 
      spanning multiple contexts. TRIAL REGISTRATION: ClinicalTrials.gov NCT04678960 ; 
      registered November 11, 2020; https://clinicaltrials.gov/ct2/show/NCT04678960 .
CI  - (c) 2021. The Author(s).
FAU - Knight, Danica Kalling
AU  - Knight DK
AUID- ORCID: 0000-0001-7488-2139
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA. d.knight@tcu.edu.
FAU - Yang, Yang
AU  - Yang Y
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Joseph, Elizabeth D
AU  - Joseph ED
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Tinius, Elaine
AU  - Tinius E
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Young, Shatoya
AU  - Young S
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Shelley, Lillyan T
AU  - Shelley LT
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Cross, David R
AU  - Cross DR
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
FAU - Knight, Kevin
AU  - Knight K
AD  - Texas Christian University, 2901 University Drive, TCU Box 298921, Fort Worth, TX 
      76129, Texas, USA.
LA  - eng
SI  - ClinicalTrials.gov/NCT04678960
GR  - UG3 DA050250/DA/NIDA NIH HHS/United States
GR  - UH3 DA050250/DA/NIDA NIH HHS/United States
GR  - 1UH3DA050250/DA/NIDA NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
DEP - 20211120
PL  - England
TA  - BMC Public Health
JT  - BMC public health
JID - 100968562
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Adolescent
MH  - Adult
MH  - *Analgesics, Opioid
MH  - Caregivers
MH  - Focus Groups
MH  - Humans
MH  - *Opioid-Related Disorders/prevention & control
MH  - Violence
PMC - PMC8605598
OTO - NOTNLM
OT  - Hybrid type I design
OT  - Justice-involved youth
OT  - Prevention intervention for opioid use
OT  - Trauma-informed care
OT  - Trust-based relational intervention
COIS- The authors declare that they have no competing interests.
EDAT- 2021/11/22 06:00
MHDA- 2021/12/15 06:00
PMCR- 2021/11/20
CRDT- 2021/11/21 20:22
PHST- 2021/07/30 00:00 [received]
PHST- 2021/10/29 00:00 [accepted]
PHST- 2021/11/21 20:22 [entrez]
PHST- 2021/11/22 06:00 [pubmed]
PHST- 2021/12/15 06:00 [medline]
PHST- 2021/11/20 00:00 [pmc-release]
AID - 10.1186/s12889-021-12127-3 [pii]
AID - 12127 [pii]
AID - 10.1186/s12889-021-12127-3 [doi]
PST - epublish
SO  - BMC Public Health. 2021 Nov 20;21(1):2133. doi: 10.1186/s12889-021-12127-3.