PMID- 34809614 OWN - NLM STAT- MEDLINE DCOM- 20220124 LR - 20240404 IS - 1472-6947 (Electronic) IS - 1472-6947 (Linking) VI - 21 IP - 1 DP - 2021 Nov 22 TI - A home-based pulmonary rehabilitation mHealth system to enhance the exercise capacity of patients with COPD: development and evaluation. PG - 325 LID - 10.1186/s12911-021-01694-5 [doi] LID - 325 AB - BACKGROUND: Patients with chronic obstructive pulmonary disease (COPD) experience deficits in exercise capacity and physical activity as their disease progresses. Pulmonary rehabilitation (PR) can enhance exercise capacity of patients and it is crucial for patients to maintain a lifestyle which is long-term physically active. This study aimed to develop a home-based rehabilitation mHealth system incorporating behavior change techniques (BCTs) for COPD patients, and evaluate its technology acceptance and feasibility. METHODS: Guided by the medical research council (MRC) framework the process of this study was divided into four steps. In the first step, the prescription was constructed. The second step was to formulate specific intervention functions based on the behavior change wheel theory. Subsequently, in the third step we conducted iterative system development. And in the last step two pilot studies were performed, the first was for the improvement of system functions and the second was to explore potential clinical benefits and validate the acceptance and usability of the system. RESULTS: A total of 17 participants were enrolled, among them 12 COPD participants completed the 12-week study. For the clinical outcomes, Six-Minute Walk Test (6MWT) showed significant difference (P = .023) over time with an improvement exceeded the minimal clinically important difference (MCID). Change in respiratory symptom (CAT score) was statistically different (P = .031) with a greater decrease of - 3. The mMRC levels reduced overall and showed significant difference. The overall compliance of this study reached 82.20% (+/- 1.68%). The results of questionnaire and interviews indicated good technology acceptance and functional usability. The participants were satisfied with the mHealth-based intervention. CONCLUSIONS: This study developed a home-based PR mHealth system for COPD patients. We showed that the home-based PR mHealth system incorporating BCTs is a feasible and acceptable intervention for COPD patients, and COPD patients can benefit from the intervention delivered by the system. The proposed system played an important auxiliary role in offering exercise prescription according to the characteristics of patients. It provided means and tools for further individuation of exercise prescription in the future. CI - (c) 2021. The Author(s). FAU - Deng, Ning AU - Deng N AD - College of Biomedical Engineering and Instrument Science, Ministry of Education Key Laboratory of Biomedical Engineering, Zhejiang University, Hangzhou, China. AD - Alibaba-Zhejiang University Joint Research Center of Future Digital Healthcare, Hangzhou, China. FAU - Sheng, Leiyi AU - Sheng L AD - College of Biomedical Engineering and Instrument Science, Ministry of Education Key Laboratory of Biomedical Engineering, Zhejiang University, Hangzhou, China. FAU - Jiang, Wangshu AU - Jiang W AD - College of Biomedical Engineering and Instrument Science, Ministry of Education Key Laboratory of Biomedical Engineering, Zhejiang University, Hangzhou, China. FAU - Hao, Yongfa AU - Hao Y AD - Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. FAU - Wei, Shuoshuo AU - Wei S AD - Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. FAU - Wang, Bei AU - Wang B AD - Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. FAU - Duan, Huilong AU - Duan H AD - College of Biomedical Engineering and Instrument Science, Ministry of Education Key Laboratory of Biomedical Engineering, Zhejiang University, Hangzhou, China. FAU - Chen, Juan AU - Chen J AD - Department of Pulmonary and Critical Care Medicine, General Hospital of Ningxia Medical University, Yinchuan, 750004, Ningxia, China. chenjuan7419@163.com. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20211122 PL - England TA - BMC Med Inform Decis Mak JT - BMC medical informatics and decision making JID - 101088682 SB - IM MH - Exercise Tolerance MH - Humans MH - *Pulmonary Disease, Chronic Obstructive/therapy MH - Quality of Life MH - *Telemedicine MH - Walk Test PMC - PMC8607968 OTO - NOTNLM OT - Behavior change wheel OT - COPD OT - Pulmonary rehabilitation OT - mHealth COIS- The authors declare that they have no competing interests. EDAT- 2021/11/24 06:00 MHDA- 2022/01/27 06:00 PMCR- 2021/11/22 CRDT- 2021/11/23 05:34 PHST- 2021/06/07 00:00 [received] PHST- 2021/11/16 00:00 [accepted] PHST- 2021/11/23 05:34 [entrez] PHST- 2021/11/24 06:00 [pubmed] PHST- 2022/01/27 06:00 [medline] PHST- 2021/11/22 00:00 [pmc-release] AID - 10.1186/s12911-021-01694-5 [pii] AID - 1694 [pii] AID - 10.1186/s12911-021-01694-5 [doi] PST - epublish SO - BMC Med Inform Decis Mak. 2021 Nov 22;21(1):325. doi: 10.1186/s12911-021-01694-5.