PMID- 34812325 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211124 IS - 2168-8184 (Print) IS - 2168-8184 (Electronic) IS - 2168-8184 (Linking) VI - 13 IP - 10 DP - 2021 Oct TI - Atypical Mycobacterial Tenosynovitis in the Setting of Adalimumab Use. PG - e18952 LID - 10.7759/cureus.18952 [doi] LID - e18952 AB - Tumor necrosis factor-alpha (TNF-alpha) inhibitors indicated in the management of psoriasis, rheumatoid arthritis, ulcerative colitis, Crohn's disease, and other autoimmune diseases have been associated with the development of mycobacterial and other opportunistic infections. The majority of mycobacterial infections diagnosed in patients taking TNF-alpha inhibitors are secondary to Mycobacterium tuberculosis. Atypical mycobacteria have also been identified in this patient population, most commonly manifested by pulmonary or disseminated infections. Extra-pulmonary manifestations such as bone and joint infections are rare. We describe a case of atypical mycobacterial tenosynovitis in the setting of adalimumab use in a patient with psoriasis. This is a rarely reported complication that one should be aware of when prescribing these medications. CI - Copyright (c) 2021, Patel et al. FAU - Patel, Jay AU - Patel J AD - Internal Medicine, Orange Park Medical Center, Orange Park, USA. FAU - Guzman, Nilmarie AU - Guzman N AD - Internal Medicine, Orange Park Medical Center, Orange Park, USA. FAU - Wukitsch, Kurt AU - Wukitsch K AD - Internal Medicine, Orange Park Medical Center, Orange Park, USA. LA - eng PT - Case Reports DEP - 20211021 PL - United States TA - Cureus JT - Cureus JID - 101596737 PMC - PMC8604424 OTO - NOTNLM OT - adalimumab OT - musculoskeletal OT - nontuberculous mycobacterium OT - psoriasis OT - tenosynovitis COIS- The authors have declared financial relationships, which are detailed in the next section. EDAT- 2021/11/24 06:00 MHDA- 2021/11/24 06:01 PMCR- 2021/10/21 CRDT- 2021/11/23 09:26 PHST- 2021/10/20 00:00 [accepted] PHST- 2021/11/23 09:26 [entrez] PHST- 2021/11/24 06:00 [pubmed] PHST- 2021/11/24 06:01 [medline] PHST- 2021/10/21 00:00 [pmc-release] AID - 10.7759/cureus.18952 [doi] PST - epublish SO - Cureus. 2021 Oct 21;13(10):e18952. doi: 10.7759/cureus.18952. eCollection 2021 Oct.