PMID- 34812993
OWN - NLM
STAT- MEDLINE
DCOM- 20220308
LR  - 20220531
IS  - 1865-8652 (Electronic)
IS  - 0741-238X (Linking)
VI  - 39
IP  - 1
DP  - 2022 Jan
TI  - Comparative Effectiveness and Safety of Open-Door Laminoplasty, French-Door 
      Laminoplasty, Laminectomy and Fusion, and Laminectomy Alone for Multilevel 
      Degenerative Cervical Myelopathy: A Bayesian Network Analysis.
PG  - 117-139
LID - 10.1007/s12325-021-01980-8 [doi]
AB  - OBJECTIVES: To evaluate the comparative effectiveness and safety of open-door 
      laminoplasty (OLP), French-door laminoplasty (FLP), laminectomy and fusion (LF), 
      and laminectomy alone (LA) in treating multilevel degenerative cervical 
      myelopathy (MDCM). METHODS: Embase, PubMed, and Cochrane library were searched 
      from their inception date to 7 January 2021. Randomized controlled trials and 
      cohort studies comparing OLP, FLP, LF, and LA were identified to perform a 
      network meta-analysis (NMA). RESULTS: A total of 30 studies with 2671 patients 
      were included. Our NMA results showed no significant difference between LF and 
      OLP, but both are superior to LA and FLP in the comparison of JOA (Japanese 
      Orthopaedic Association) score improvement. LF showed a most unsatisfactory 
      outcome in postoperative range of motion (ROM) compared with LA or OLP or with 
      FLP. For the complication outcome, no significant differences were found. The 
      surface under the cumulative ranking curves (SUCRA) for JOA improvement was as 
      follows: LF, OPL, LA, and FLP. For ROM reduction it was LA, OPL, FPL, and LF. For 
      complications it was LF, LA, OLP, and FLP. CONCLUSIONS: Considering all the 
      evaluated criteria, none of the procedures showed the best outcome with least 
      complications and optimal efficacy. However, OLP can be most recommended because 
      of its second-ranking spectra in both of JOA improvement and ROM reduction, also 
      with an acceptable incidence of complications, with the third least.
CI  - (c) 2021. The Author(s), under exclusive licence to Springer Healthcare Ltd., part 
      of Springer Nature.
FAU - Li, Xian
AU  - Li X
AD  - Department of Orthopedic and Trauma Surgery, Xiyuan Hospital, China Academy of 
      Chinese Medical Science, Beijing, 100091, China.
FAU - Yu, Hui
AU  - Yu H
AD  - Department of Orthopedic and Trauma Surgery, University Hospital Bonn, 53127, 
      Bonn, Germany.
AD  - Department of Orthopedics, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, 510080, China.
FAU - Welle, Kristian
AU  - Welle K
AD  - Department of Orthopedic and Trauma Surgery, University Hospital Bonn, 53127, 
      Bonn, Germany.
FAU - Gathen, Martin
AU  - Gathen M
AD  - Department of Orthopedic and Trauma Surgery, University Hospital Bonn, 53127, 
      Bonn, Germany.
FAU - Zhang, Li
AU  - Zhang L
AD  - Department of Orthopedic and Trauma Surgery, University Hospital Bonn, 53127, 
      Bonn, Germany.
FAU - Xiao, Jin
AU  - Xiao J
AD  - Department of Orthopedics, Guangdong Provincial People's Hospital, Guangdong 
      Academy of Medical Sciences, Guangzhou, 510080, China. xiaojinhn@163.com.
FAU - Kabir, Koroush
AU  - Kabir K
AUID- ORCID: 0000-0002-0110-7745
AD  - Department of Orthopedic and Trauma Surgery, University Hospital Bonn, 53127, 
      Bonn, Germany. Koroush.Kabir@ukbonn.de.
LA  - eng
PT  - Journal Article
PT  - Meta-Analysis
PT  - Review
DEP - 20211123
PL  - United States
TA  - Adv Ther
JT  - Advances in therapy
JID - 8611864
MH  - Bayes Theorem
MH  - Cervical Vertebrae/surgery
MH  - Humans
MH  - Laminectomy/adverse effects/methods
MH  - *Laminoplasty/adverse effects/methods
MH  - Network Meta-Analysis
MH  - Retrospective Studies
MH  - *Spinal Cord Diseases/surgery
MH  - Treatment Outcome
OTO - NOTNLM
OT  - French-door laminoplasty
OT  - Laminectomy alone
OT  - Laminectomy and fusion
OT  - Multilevel degenerative cervical myelopathy
OT  - Network meta-analysis
OT  - Open-door laminoplasty
EDAT- 2021/11/24 06:00
MHDA- 2022/03/09 06:00
CRDT- 2021/11/23 12:26
PHST- 2021/07/28 00:00 [received]
PHST- 2021/10/28 00:00 [accepted]
PHST- 2021/11/24 06:00 [pubmed]
PHST- 2022/03/09 06:00 [medline]
PHST- 2021/11/23 12:26 [entrez]
AID - 10.1007/s12325-021-01980-8 [pii]
AID - 10.1007/s12325-021-01980-8 [doi]
PST - ppublish
SO  - Adv Ther. 2022 Jan;39(1):117-139. doi: 10.1007/s12325-021-01980-8. Epub 2021 Nov 
      23.