PMID- 34819265 OWN - NLM STAT- MEDLINE DCOM- 20220627 LR - 20220711 IS - 1934-8150 (Electronic) IS - 1551-7411 (Linking) VI - 18 IP - 8 DP - 2022 Aug TI - Attention to price disclosures in direct-to-consumer prescription drug advertising and the impact on drug perceptions. PG - 3402-3413 LID - S1551-7411(21)00374-0 [pii] LID - 10.1016/j.sapharm.2021.11.003 [doi] AB - BACKGROUND: Mandatory disclosure of the price of prescription drugs within direct-to-consumer pharmaceutical advertisements (DTCA) has been proposed as a potential means of curbing rising drug costs in the United States. While price transparency in DTCA has widespread public support, empirical evidence regarding the effects of such drug prices disclosures remains limited. OBJECTIVES: This study assessed the degree to which a price disclosure was noticed, the individual characteristics associated with price disclosure recognition, and the impact on perceived drug affordability, effectiveness, and safety. METHODS: A randomized experiment was conducted among 2,138 members of the Amerispeak online panel. Participants were shown a television commercial for a drug treating either type II diabetes, deep vein thrombosis/pulmonary embolism (DVT/PE), or rheumatoid arthritis (RA) that disclosed the list price, disclosed the list price plus the average out-of-pocket cost, or had no price disclosure. RESULTS: Roughly forty percent of participants noticed when a price was disclosed while 20-24% noticed information about individual costs varying (the higher of these percentages occurred when the average out-of-pocket cost was provided). Attention did not vary systematically with the cost amount. Recognition of the different elements of the price disclosure were most predicted by sociodemographic variables such as race, education, and income as well as health characteristics. Price disclosure altered perceived affordability of the advertised medication in a manner consistent with the costs provided, but such consistent significant effects were not found for perceived drug effectiveness and safety. CONCLUSIONS: Repeated exposure to price disclosure in television DTCA or supplementary sources of price information may be necessary to increase attention to drug price information, especially among those who are most vulnerable to the burden of drug costs. Price transparency appears useful for adjusting affordability perceptions, but additional research needs to examine how such perceptions factor into healthcare decision-making and drug pricing. CI - Copyright (c) 2021 Elsevier Inc. All rights reserved. FAU - Ball, Jennifer Gerard AU - Ball JG AD - Department of Advertising and Public Relations, Klein College of Communication, Temple University, 300 Annenberg Hall, Philadelphia, PA, 19122, United States. Electronic address: jennifer.gerard.ball@temple.edu. FAU - Hollin, Ilene L AU - Hollin IL AD - Department of Health Services Administration and Policy, College of Public Health, Temple University, 1301 Cecil B. Moore Ave, Philadelphia, PA, 19122, United States. Electronic address: ilene.hollin@temple.edu. LA - eng PT - Journal Article PT - Randomized Controlled Trial PT - Research Support, U.S. Gov't, Non-P.H.S. DEP - 20211112 PL - United States TA - Res Social Adm Pharm JT - Research in social & administrative pharmacy : RSAP JID - 101231974 RN - 0 (Prescription Drugs) SB - IM MH - Advertising MH - *Diabetes Mellitus, Type 2 MH - *Direct-to-Consumer Advertising MH - Disclosure MH - Humans MH - *Prescription Drugs MH - United States OTO - NOTNLM OT - Affordability OT - Attention OT - Direct-to-consumer prescription drug advertising OT - Price disclosure OT - Price transparency OT - Recognition EDAT- 2021/11/26 06:00 MHDA- 2022/06/28 06:00 CRDT- 2021/11/25 05:46 PHST- 2021/08/06 00:00 [received] PHST- 2021/10/25 00:00 [revised] PHST- 2021/11/10 00:00 [accepted] PHST- 2021/11/26 06:00 [pubmed] PHST- 2022/06/28 06:00 [medline] PHST- 2021/11/25 05:46 [entrez] AID - S1551-7411(21)00374-0 [pii] AID - 10.1016/j.sapharm.2021.11.003 [doi] PST - ppublish SO - Res Social Adm Pharm. 2022 Aug;18(8):3402-3413. doi: 10.1016/j.sapharm.2021.11.003. Epub 2021 Nov 12.