PMID- 34821486 OWN - NLM STAT- MEDLINE DCOM- 20211129 LR - 20220531 IS - 0009-0875 (Print) IS - 0009-0875 (Linking) VI - 65 IP - 4 DP - 2020 Dec 31 TI - Comparison of glycaemic control and anthropometric parameters before and after Ramadan fasting in a selected cohort of patients with type 2 diabetes mellitus in Sri Lanka. PG - 79-85 LID - 10.4038/cmj.v65i4.9276 [doi] AB - INTRODUCTION: The majority of Sri Lankan Moors fast during Ramadan. This may have an effect on their glycaemic control and anthropometric parameters. However, limited information exists about the impact of Ramadan fasting on diabetes in Sri Lanka. OBJECTIVES: The main objective of this study was to investigate the effect of Ramadan fasting on glycaemic control and anthropometric parameters in patients with type 2 diabetes mellitus (T2DM). Patients were also observed for symptoms of hypoglycaemia, timing and association with different antidiabetic agents. METHODS: One hundred and twenty Sri Lankan Moors with T2DM were recruited for this study. Biochemical investigations and anthropometric parameters were done before and after Ramadan fasting. The statistical analysis was done with paired t test to compare glycaemic control and anthropometric parameters before and after Ramadan. RESULTS: There was a significant decrease in body weight (mean body weight 66.17 to 65.52 kg; p= < 0.001) and waist circumference (93.84 to 92.16cm; p= < 0.001). However, the glycaemic control worsened in all patients during Ramadan with rise in mean fructosamine value of 354.1 to 996.9micromol/L. Out of 104 participants 43 participants experienced symptoms of hypoglycaemia. CONCLUSIONS: The current study showed an improvement in the body weight and waist circumference during Ramadan fasting, however the glycaemic control has been worsened. More follow-up studies are warranted in order to draw a conclusion on the effect of Ramadan fasting in glycaemic control and anthropometric parameters in diabetes patients. FAU - Shafras, Mohamed S AU - Shafras M S AD - Postgraduate Institute of Science, University of Peradeniya, Sri Lanka, way2shafraz@gmail.com. FAU - Monaragala, Lakshika M AU - Monaragala L M AD - Department of Diabetes and Endocrinology, National Hospital, Kandy, Sri Lanka. FAU - Samarakkody, Isha S AU - Samarakkody I S FAU - Ahamed, Rafeek A AU - Ahamed R A FAU - Nawarathna, Lakshika N AU - Nawarathna L N AD - Department of Statistics and Computer Science, University of Peradeniya, Sri Lanka. FAU - Sanas, Mohamed S AU - Sanas M S FAU - Antonypillai, Charles A AU - Antonypillai C A LA - eng PT - Journal Article PL - Sri Lanka TA - Ceylon Med J JT - The Ceylon medical journal JID - 1264702 RN - 0 (Blood Glucose) RN - 0 (Hypoglycemic Agents) SB - IM MH - Blood Glucose MH - Body Weight MH - *Diabetes Mellitus, Type 2/drug therapy MH - *Fasting MH - *Glycemic Control MH - Humans MH - Hypoglycemic Agents/administration & dosage MH - Islam MH - Sri Lanka MH - Waist Circumference OTO - NOTNLM OT - : Ramadan Fasting, Diabetes Mellitus, Glycaemic control, Fructosamine. EDAT- 2021/11/26 06:00 MHDA- 2021/11/30 06:00 CRDT- 2021/11/25 09:27 PHST- 2021/11/25 09:27 [entrez] PHST- 2021/11/26 06:00 [pubmed] PHST- 2021/11/30 06:00 [medline] AID - 10.4038/cmj.v65i4.9276 [doi] PST - ppublish SO - Ceylon Med J. 2020 Dec 31;65(4):79-85. doi: 10.4038/cmj.v65i4.9276.