PMID- 34822631 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211130 IS - 2306-7381 (Electronic) IS - 2306-7381 (Linking) VI - 8 IP - 11 DP - 2021 Nov 1 TI - Bilateral Renal Large B Cell Lymphoma in a Dog: A Case Report and Review of the Literature. LID - 10.3390/vetsci8110258 [doi] LID - 258 AB - Canine lymphoma is a commonly reported neoplasia and, in most dogs, arises from lymph nodes before spreading to other organs. Renal lymphoma rarely occurs, and kidneys usually are a secondary site of origin. Primary renal lymphoma is infrequently described in the veterinary literature. In this study, we present a rare case of primary renal lymphoma in a dog and a review of similar cases. A 3-year-old male dog was admitted due to anorexia, weakness and vomiting. Clinical examination revealed bilaterally enlarged kidneys. Imaging demonstrated the presence of multiple renal masses. Cytology of abdominal fluid and kidneys led to the diagnosis of large cell lymphoma. Histopathology and immunohistochemistry on tissue samples taken from the kidneys confirmed the cytological diagnosis of lymphoma and categorized it as primary bilateral renal large B-cell lymphoma (LBCL). FAU - Apostolopoulou, Emmanouela P AU - Apostolopoulou EP AUID- ORCID: 0000-0002-7642-7946 AD - Department of Pathology, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece. FAU - Vlemmas, Ioannis AU - Vlemmas I AD - Department of Pathology, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece. FAU - Pardali, Dimitra AU - Pardali D AD - Diagnostic Laboratory, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thesssaloniki, 54627 Thessaloniki, Greece. FAU - Adamama-Moraitou, Katerina K AU - Adamama-Moraitou KK AD - Companion Animal Clinic (Medicine Unit), Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thesssaloniki, 54627 Thessaloniki, Greece. FAU - Poutahidis, Theofilos AU - Poutahidis T AD - Department of Pathology, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece. FAU - Papadopoulou, Paraskevi L AU - Papadopoulou PL AD - Department of Diagnostic Imaging, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thesssaloniki, 54627 Thessaloniki, Greece. FAU - Brellou, Georgia D AU - Brellou GD AUID- ORCID: 0000-0003-0588-7256 AD - Department of Pathology, Faculty of Health Sciences, School of Veterinary Medicine, Aristotle University of Thessaloniki, 54627 Thessaloniki, Greece. LA - eng PT - Case Reports DEP - 20211101 PL - Switzerland TA - Vet Sci JT - Veterinary sciences JID - 101680127 PMC - PMC8624832 OTO - NOTNLM OT - B-cell OT - canine OT - immunohistochemistry OT - kidneys OT - lymphoma OT - neoplasia COIS- The authors declare no conflict of interest. EDAT- 2021/11/26 06:00 MHDA- 2021/11/26 06:01 PMCR- 2021/11/01 CRDT- 2021/11/25 17:10 PHST- 2021/10/06 00:00 [received] PHST- 2021/10/25 00:00 [revised] PHST- 2021/10/27 00:00 [accepted] PHST- 2021/11/25 17:10 [entrez] PHST- 2021/11/26 06:00 [pubmed] PHST- 2021/11/26 06:01 [medline] PHST- 2021/11/01 00:00 [pmc-release] AID - vetsci8110258 [pii] AID - vetsci-08-00258 [pii] AID - 10.3390/vetsci8110258 [doi] PST - epublish SO - Vet Sci. 2021 Nov 1;8(11):258. doi: 10.3390/vetsci8110258.