PMID- 34828892
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20240407
IS  - 2304-8158 (Print)
IS  - 2304-8158 (Electronic)
IS  - 2304-8158 (Linking)
VI  - 10
IP  - 11
DP  - 2021 Oct 28
TI  - Dissipation Dynamics, Terminal Residues and Dietary Risk Assessment of Two 
      Isomers of Dimethacarb in Rice by HPLC-MS/MS.
LID - 10.3390/foods10112615 [doi]
LID - 2615
AB  - Dimethacarb is a carbamate insecticide developed in China that contains 
      3,5-dimethylphenyl methylcarbamate (XMC) and 3,4-dimethylphenyl methylcarbamate 
      (MPMC) isomers. Dimethacarb has been registered for use in rice in China, but no 
      residue or degradation of dimethacarb in rice has been reported and the maximum 
      residue limits (MRLs) for rice have not been established. A versatile 
      high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) 
      method was developed with modified QuEChERS sample preparation to determine two 
      isomers of dimethacarb in rice. The average recovery of XMC and MPMC in brown 
      rice, rice husk, and rice straw ranged from 71.69 to 100.60%, with spike levels 
      of 0.01 to 1 mg/kg and relative standard deviations (RSDs) of 0.21 to 8.41%. 
      Field experiments showed that the half-lives of XMC and MPMC in rice straw were 
      4.08 to 4.23 days and 3.48 to 3.69 days, respectively. Final residues of XMC and 
      MPMC in rice husk after 21 days of spraying at six sites ranged from 0.23-2.65 
      mg/kg and 0.06-1.10 mg/kg, and <0.01-0.16 mg/kg and <0.01-0.04 mg/kg in brown 
      rice. The ratio of XMC to MPMC content in the rice husk differed from the 
      original 50% dimethacarb EC, indicating the difference in the degradation rate of 
      XMC and MPMC. The estimated risk quotient (RQ) for both XMC and MPMC was less 
      than 30%. These data for residues from six representative locations could provide 
      a reference for establishing the MRL of dimethacarb in rice.
FAU - Tang, Shouying
AU  - Tang S
AUID- ORCID: 0000-0001-7340-1057
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
FAU - Meng, Xiurou
AU  - Meng X
AUID- ORCID: 0000-0001-7574-0001
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
FAU - Wang, Yongkang
AU  - Wang Y
AD  - Clinical Laboratory, Qufu City Center for Disease Control and Prevention, Jining 
      273100, China.
FAU - Shi, Xueqin
AU  - Shi X
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
FAU - Feng, Tianyou
AU  - Feng T
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
FAU - Hu, Deyu
AU  - Hu D
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
FAU - Zhang, Yuping
AU  - Zhang Y
AUID- ORCID: 0000-0002-5494-3747
AD  - State Key Laboratory Breeding Base of Green Pesticide and Agricultural 
      Bioengineering, Key Laboratory of Green Pesticide and Agricultural 
      Bioengineering, Ministry of Education, Guizhou University, Guiyang 550025, China.
LA  - eng
GR  - No.21866009/the National Natural Science Foundation of China/
GR  - No. [2018]5781/the Technology Programs of Guizhou Province/
GR  - 111 Program, D20023/the Program of Introducing Talents of Discipline to 
      Universities of China/
GR  - Qianjiaohe KY number (2020)004/the Frontiers Science Center for Asymmetric 
      Synthesis and Medicinal Molecules, Department of Education, Guizhou Province/
PT  - Journal Article
DEP - 20211028
PL  - Switzerland
TA  - Foods
JT  - Foods (Basel, Switzerland)
JID - 101670569
PMC - PMC8623593
OTO - NOTNLM
OT  - HPLC-MS/MS
OT  - degradation
OT  - dimethacarb
OT  - residues
OT  - rice
OT  - risk assessment
COIS- The authors declare no conflict of interest.
EDAT- 2021/11/28 06:00
MHDA- 2021/11/28 06:01
PMCR- 2021/10/28
CRDT- 2021/11/27 01:07
PHST- 2021/09/28 00:00 [received]
PHST- 2021/10/21 00:00 [revised]
PHST- 2021/10/25 00:00 [accepted]
PHST- 2021/11/27 01:07 [entrez]
PHST- 2021/11/28 06:00 [pubmed]
PHST- 2021/11/28 06:01 [medline]
PHST- 2021/10/28 00:00 [pmc-release]
AID - foods10112615 [pii]
AID - foods-10-02615 [pii]
AID - 10.3390/foods10112615 [doi]
PST - epublish
SO  - Foods. 2021 Oct 28;10(11):2615. doi: 10.3390/foods10112615.