PMID- 34845067 OWN - NLM STAT- MEDLINE DCOM- 20211206 LR - 20211214 IS - 2044-6055 (Electronic) IS - 2044-6055 (Linking) VI - 11 IP - 11 DP - 2021 Nov 29 TI - Degree of personalisation in tailored activities and its effect on behavioural and psychological symptoms and quality of life among people with dementia: a systematic review and meta-analysis. PG - e048917 LID - 10.1136/bmjopen-2021-048917 [doi] LID - e048917 AB - OBJECTIVES: To understand and assess the degree of personalisation of tailored activities for people with dementia (PWD); and to estimate the magnitude of the effects of levels of personalisation on reducing behavioural and psychological symptoms of dementia (BPSD), improving quality of life (QoL) and level of engagement. DESIGN: Systematic review with meta-analysis. DATA SOURCES: ProQuest, PubMed, Ovid, Cochrane Library, Web of Science and CINAHL were searched from the start of indexing to May 2020. ELIGIBILITY CRITERIA: We included randomised controlled trials and quasi-experimental studies assessing the effects of tailored activities for people aged 60 years or older with dementia or cognitive impairment on the outcomes of BPSD, QoL, depression and level of engagement with control groups. DATA EXTRACTION AND SYNTHESIS: Two researchers screened studies, extracted data and assessed risks of bias. A rating scheme to assess the degree of personalisation of tailored activities was developed to classify tailored activities into high/medium/low groups. Effect sizes were expressed using standardised mean differences at 95% Confidence Interval (CI). Subgroup analyses were conducted to assess whether the degree of personalisation of tailored activities affected outcomes of interest. RESULTS: Thirty-five studies covering 2390 participants from 16 countries/regions were identified. Studies with a high-level of personalisation interventions (n=8) had a significant and moderate effect on reducing BPSD (standardised mean differences, SMD=-0.52, p<0.05), followed by medium (n=6; SMD=-0.38, p=0.071) and low-level personalisation interventions (n=6; SMD=-0.15, p=0.076). Tailored activities with a high-level of personalisation had a moderate effect size on improving QoL (n=5; SMD=0.52, p<0.05), followed by a medium level (n=3; SMD=0.41, p<0.05) of personalisation. CONCLUSIONS: To develop high-level tailored activities to reduce BPSD and improve QoL among PWD, we recommend applying comprehensive assessments to identify and address two or more PWD characteristics in designed tailored activities and allow modification of interventions to respond to changing PWD needs/circumstances. PROSPERO REGISTRATION NUMBER: CRD42020168556. CI - (c) Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. FAU - Lu, Shiyu AU - Lu S AUID- ORCID: 0000-0002-9355-4883 AD - Department of Social and Behavioural Sciences, City University of Hong Kong, Hong Kong, Hong Kong, Hong Kong. FAU - Zhang, Anna Y AU - Zhang AY AD - Department of Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong. FAU - Liu, Tianyin AU - Liu T AD - Department of Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong. FAU - Choy, Jacky C P AU - Choy JCP AD - Department of Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong. FAU - Ma, Maggie S L AU - Ma MSL AD - Department of Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong. FAU - Wong, Gloria AU - Wong G AUID- ORCID: 0000-0002-1331-942X AD - Department of Social Work and Social Administration, Sau Po Centre on Ageing, University of Hong Kong, Hong Kong, Hong Kong. FAU - Lum, Terry AU - Lum T AUID- ORCID: 0000-0003-1196-5345 AD - Department of Social Work and Social Administration, University of Hong Kong, Hong Kong, Hong Kong tlum@hku.hk. LA - eng PT - Journal Article PT - Meta-Analysis PT - Research Support, Non-U.S. Gov't PT - Systematic Review DEP - 20211129 PL - England TA - BMJ Open JT - BMJ open JID - 101552874 SB - IM MH - *Cognitive Dysfunction MH - *Dementia MH - Humans MH - Quality of Life PMC - PMC8634002 OTO - NOTNLM OT - dementia OT - mental health OT - old age psychiatry COIS- Competing interests: None declared. EDAT- 2021/12/01 06:00 MHDA- 2021/12/15 06:00 PMCR- 2021/11/29 CRDT- 2021/11/30 06:09 PHST- 2021/11/30 06:09 [entrez] PHST- 2021/12/01 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2021/11/29 00:00 [pmc-release] AID - bmjopen-2021-048917 [pii] AID - 10.1136/bmjopen-2021-048917 [doi] PST - epublish SO - BMJ Open. 2021 Nov 29;11(11):e048917. doi: 10.1136/bmjopen-2021-048917.