PMID- 34853606 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20211203 IS - 1176-2322 (Print) IS - 1754-2103 (Electronic) IS - 1176-2322 (Linking) VI - 2021 DP - 2021 TI - A Comparison of Dynamic and Static Hip-Knee-Ankle Angle during Gait in Knee Osteoarthritis Patients and Healthy Individuals. PG - 6231406 LID - 10.1155/2021/6231406 [doi] LID - 6231406 AB - Malalignment of the lower limbs is the main biomechanical factor for knee osteoarthritis (KOA). The static hip-knee-ankle angle (S-HKAA) measured from radiograph is regarded as the "gold standard" of the malalignment. However, many evidences showed that the S-HKAA has no significant correlation with the knee dynamic-load distribution, unlike the dynamic HKAA (D-HKAA). The purpose of this study was to quantitatively analyze the D-HKAA and investigate the relationship between D-HKAA and S-HKAA for both KOA and healthy participants. In this paper, twenty-five healthy subjects and twenty-five medial compartment KOA (M-KOA) patients were recruited. Three-dimensional motion analysis and standing lower-limbs-full-length radiograph were utilized to obtain the D-HKAA and S-HKAA, respectively. The results showed that the mean D-HKAA was more varus than the S-HKAA (p < 0.05). For the mean D-HKAA, larger varus angle was observed in swing phase than stance phase (p < 0.05). Compared with healthy subjects, the M-KOA patients had remarkably smaller S-HKAA and D-HKAA during gait cycle (p < 0.01). For the relationship between the S-HKAA and mean D-HKAA, no significant correlation was found for both healthy subjects and M-KOA patients (r < 0.357, n = 25, p > 0.05, Spearman correlation analysis). In conclusion, the S-HKAA was limited to predict the D-HKAA for both M-KOA patients and healthy subjects. The D-HKAA should be given more attention to the orthopedist and the designer of knee brace and orthotics. CI - Copyright (c) 2021 Li Zhang et al. FAU - Zhang, Li AU - Zhang L AUID- ORCID: 0000-0002-2535-3668 AD - Innovation Center of Bioengineering, Shaanxi Engineering Laboratory for Transmissions and Controls, Northwestern Polytechnical University, Xi'an 710072, China. FAU - Liu, Geng AU - Liu G AUID- ORCID: 0000-0003-1940-1253 AD - Innovation Center of Bioengineering, Shaanxi Engineering Laboratory for Transmissions and Controls, Northwestern Polytechnical University, Xi'an 710072, China. FAU - Han, Bing AU - Han B AUID- ORCID: 0000-0001-5820-8013 AD - Innovation Center of Bioengineering, Shaanxi Engineering Laboratory for Transmissions and Controls, Northwestern Polytechnical University, Xi'an 710072, China. FAU - Yan, Yuzhou AU - Yan Y AUID- ORCID: 0000-0001-8671-1089 AD - Innovation Center of Bioengineering, Shaanxi Engineering Laboratory for Transmissions and Controls, Northwestern Polytechnical University, Xi'an 710072, China. FAU - Fei, Junhua AU - Fei J AUID- ORCID: 0000-0001-5842-1092 AD - Innovation Center of Bioengineering, Shaanxi Engineering Laboratory for Transmissions and Controls, Northwestern Polytechnical University, Xi'an 710072, China. FAU - Ma, Jianbing AU - Ma J AUID- ORCID: 0000-0001-6513-5713 AD - Honghui Hospital, Xi'an Jiaotong University College of Medicine, Xi'an 710054, China. FAU - Zhang, Yunfei AU - Zhang Y AUID- ORCID: 0000-0001-7930-5189 AD - Tangdu Hospital, Air Force Medical University, Xi'an 710038, China. LA - eng PT - Journal Article DEP - 20211122 PL - Egypt TA - Appl Bionics Biomech JT - Applied bionics and biomechanics JID - 101208624 PMC - PMC8629624 COIS- The authors declare that they have no conflicts of interest. EDAT- 2021/12/03 06:00 MHDA- 2021/12/03 06:01 PMCR- 2021/11/22 CRDT- 2021/12/02 06:36 PHST- 2021/07/06 00:00 [received] PHST- 2021/11/08 00:00 [accepted] PHST- 2021/12/02 06:36 [entrez] PHST- 2021/12/03 06:00 [pubmed] PHST- 2021/12/03 06:01 [medline] PHST- 2021/11/22 00:00 [pmc-release] AID - 10.1155/2021/6231406 [doi] PST - epublish SO - Appl Bionics Biomech. 2021 Nov 22;2021:6231406. doi: 10.1155/2021/6231406. eCollection 2021.