PMID- 34856505
OWN - NLM
STAT- MEDLINE
DCOM- 20220111
LR  - 20220111
IS  - 1873-3778 (Electronic)
IS  - 0021-9673 (Linking)
VI  - 1661
DP  - 2022 Jan 4
TI  - Synthesis of a covalent organic framework with hydrazine linkages and its 
      application in open-tubular capillary electrochromatography.
PG  - 462681
LID - S0021-9673(21)00803-7 [pii]
LID - 10.1016/j.chroma.2021.462681 [doi]
AB  - Recently, covalent organic frameworks (COFs), owning to their excellent and 
      unique properties, are attracting the attention of numerous researchers in some 
      areas, especially the domain of chromatographic separation. However, the 
      application of hydrazine linkages COFs in open-tubular capillary 
      electrochromatography (OT-CEC) lies in the early stage at present. Herein, a 
      well-crystallized hydrazine-linked COF (Tf-DHzOH) was synthesized successfully 
      from 2,5-dihydroxyterephtalohydrazide and 1,3,5-triformyl-benzene. Tf-DHzOH was 
      firstly regarded as a stationary phase material to prepare the Tf-DHzOH coated 
      capillaries with different coating thickness by covalent bonding in this work. 
      The characterization results showed that Tf-DHzOH was successfully synthesized. 
      The separation performance and stability of the Tf-DHzOH coated capillary were 
      evaluated by considering amino acids, sulfonamides, tetracyclines and benzene 
      compounds as analytes. The relative standard deviations (RSDs) of separation time 
      in the intra-day (n = 9), inter-day (n = 6), column-to-column (n = 3) and 
      batch-to-batch (n = 3) were 0.76-4.97%, 1.59-5.94%1.78-8.72% and 1.66%-8.23%, 
      respectively, the RSDs of peak areas were 1.90-5.16%, 1.73-5.24%, 1.26-7.33% and 
      3.77%-11.24%, respectively. It was confirmed that there was no visible change of 
      separation efficiency after the Tf-DHzOH-coated capillary was used more than 200 
      runs. The results make clear that 2D hydrazine-linked COF (Tf-DHzOH) has superior 
      potential as the stationary phase in OT-CEC for chromatographic separation.
CI  - Copyright (c) 2021. Published by Elsevier B.V.
FAU - Wang, Fangling
AU  - Wang F
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China.
FAU - Zhang, Yanli
AU  - Zhang Y
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China.
FAU - Wang, Guoxiu
AU  - Wang G
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China.
FAU - Qi, Shengda
AU  - Qi S
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China.
FAU - Lv, Wenjuan
AU  - Lv W
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China. Electronic address: lvwenj@lzu.edu.cn.
FAU - Liu, Juanjuan
AU  - Liu J
AD  - Cuiying Biomedical Research Center, Lanzhou University Second Hospital, Lanzhou 
      730030, China.
FAU - Chen, Hongli
AU  - Chen H
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China. Electronic address: hlchen@lzu.edu.cn.
FAU - Chen, Xingguo
AU  - Chen X
AD  - State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou 
      730000, China; College of Chemistry and Chemical Engineering, Lanzhou University, 
      Lanzhou 730000, China.
LA  - eng
PT  - Journal Article
DEP - 20211112
PL  - Netherlands
TA  - J Chromatogr A
JT  - Journal of chromatography. A
JID - 9318488
RN  - 0 (Amino Acids)
RN  - 0 (Hydrazines)
RN  - 0 (Metal-Organic Frameworks)
SB  - IM
MH  - Amino Acids
MH  - *Capillary Electrochromatography
MH  - Hydrazines
MH  - *Metal-Organic Frameworks
OTO - NOTNLM
OT  - Amino acids
OT  - Benzene compounds
OT  - Capillary electrochromatography
OT  - Hydrazine-linked COF
OT  - Sulfonamides
OT  - Tetracyclines
OT  - Tf-DHzOH
COIS- Declaration of Competing Interest The authors declare that they have no conflict 
      of interest or personal relationships that could have appeared to influence the 
      work reported here.
EDAT- 2021/12/03 06:00
MHDA- 2022/01/12 06:00
CRDT- 2021/12/02 20:21
PHST- 2021/08/26 00:00 [received]
PHST- 2021/10/24 00:00 [revised]
PHST- 2021/11/09 00:00 [accepted]
PHST- 2021/12/03 06:00 [pubmed]
PHST- 2022/01/12 06:00 [medline]
PHST- 2021/12/02 20:21 [entrez]
AID - S0021-9673(21)00803-7 [pii]
AID - 10.1016/j.chroma.2021.462681 [doi]
PST - ppublish
SO  - J Chromatogr A. 2022 Jan 4;1661:462681. doi: 10.1016/j.chroma.2021.462681. Epub 
      2021 Nov 12.