PMID- 34859142
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220925
IS  - 2372-3556 (Print)
IS  - 2372-3556 (Electronic)
IS  - 2372-3556 (Linking)
VI  - 8
IP  - 5
DP  - 2021
TI  - From mouse genetics to targeting the Rag GTPase pathway.
PG  - 1979370
LID - 10.1080/23723556.2021.1979370 [doi]
LID - 1979370
AB  - The identification of the Rag GTPases initiated the deciphering of the molecular 
      puzzle of nutrient signaling to the mechanistic target of rapamycin (mTOR), and 
      spurred interest in targeting this pathway to combat human disease. Recent mouse 
      genetic studies have provided pathophysiological insight and pointed to potential 
      indications for inhibitors of the Rag GTPase pathway.
CI  - (c) 2021 Taylor & Francis Group, LLC.
FAU - Ortega-Molina, Ana
AU  - Ortega-Molina A
AUID- ORCID: 0000-0003-2782-8994
AD  - Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre 
      (CNIO), Madrid, Spain.
FAU - Efeyan, Alejo
AU  - Efeyan A
AUID- ORCID: 0000-0002-3806-6799
AD  - Metabolism and Cell Signaling Laboratory, Spanish National Cancer Research Centre 
      (CNIO), Madrid, Spain.
LA  - eng
PT  - Journal Article
DEP - 20210924
PL  - United States
TA  - Mol Cell Oncol
JT  - Molecular & cellular oncology
JID - 101642411
PMC - PMC8632321
OTO - NOTNLM
OT  - B cells
OT  - Mtor
OT  - Rag GTPases; nutrients
OT  - lymphoma
OT  - mice
OT  - small molecules
EDAT- 2021/12/04 06:00
MHDA- 2021/12/04 06:01
PMCR- 2022/09/24
CRDT- 2021/12/03 07:09
PHST- 2021/12/03 07:09 [entrez]
PHST- 2021/12/04 06:00 [pubmed]
PHST- 2021/12/04 06:01 [medline]
PHST- 2022/09/24 00:00 [pmc-release]
AID - 1979370 [pii]
AID - 10.1080/23723556.2021.1979370 [doi]
PST - epublish
SO  - Mol Cell Oncol. 2021 Sep 24;8(5):1979370. doi: 10.1080/23723556.2021.1979370. 
      eCollection 2021.