PMID- 34861536
OWN - NLM
STAT- PubMed-not-MEDLINE
DCOM- 20211222
LR  - 20211222
IS  - 1873-3700 (Electronic)
IS  - 0031-9422 (Linking)
VI  - 194
DP  - 2022 Feb
TI  - The GH3 amidosynthetases family and their role in metabolic crosstalk modulation 
      of plant signaling compounds.
PG  - 113039
LID - S0031-9422(21)00388-5 [pii]
LID - 10.1016/j.phytochem.2021.113039 [doi]
AB  - The Gretchen Hagen 3 (GH3) genes encoding proteins belonging to the ANL 
      superfamily are widespread in the plant kingdom. The ANL superfamily consists of 
      three groups of adenylating enzymes: aryl- and acyl-CoA synthetases, firefly 
      luciferase, and amino acid-activating adenylation domains of the nonribosomal 
      peptide synthetases (NRPS). GH3s are cytosolic, acidic amidosynthetases of the 
      firefly luciferase group that conjugate auxins, jasmonates, and benzoate 
      derivatives to a wide group of amino acids. In contrast to auxins, which amide 
      conjugates mainly serve as a storage pool of inactive phytohormone or are 
      involved in the hormone degradation process, conjugation of jasmonic acid (JA) 
      results in biologically active phytohormone jasmonyl-isoleucine (JA-Ile). 
      Moreover, GH3s modulate salicylic acid (SA) concentration by conjugation of its 
      precursor, isochorismate. GH3s, as regulators of the phytohormone level, are 
      crucial for normal plant development as well as plant defense response to 
      different abiotic and biotic stress factors. Surprisingly, recent studies 
      indicate that FIN219/JAR1/GH3.11, one of the GH3 proteins, may act not only as an 
      enzyme but is also able to interact with tau-class glutathione S-transferase 
      (GSTU) and constitutive photomorphogenic 1 (COP1) proteins and regulate light and 
      stress signaling pathways. The aim of this work is to summarize our current 
      knowledge of the GH3 family.
CI  - Copyright (c) 2021 Elsevier Ltd. All rights reserved.
FAU - Wojtaczka, Patrycja
AU  - Wojtaczka P
AD  - Department of Biochemistry, Nicolaus Copernicus University in Torun, Lwowska 1, 
      87-100, Torun, Poland.
FAU - Ciarkowska, Anna
AU  - Ciarkowska A
AD  - Department of Biochemistry, Nicolaus Copernicus University in Torun, Lwowska 1, 
      87-100, Torun, Poland.
FAU - Starzynska, Ewelina
AU  - Starzynska E
AD  - Department of Biochemistry, Nicolaus Copernicus University in Torun, Lwowska 1, 
      87-100, Torun, Poland.
FAU - Ostrowski, Maciej
AU  - Ostrowski M
AD  - Department of Biochemistry, Nicolaus Copernicus University in Torun, Lwowska 1, 
      87-100, Torun, Poland. Electronic address: maciejost@umk.pl.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20211201
PL  - England
TA  - Phytochemistry
JT  - Phytochemistry
JID - 0151434
SB  - IM
OTO - NOTNLM
OT  - Amide conjugates
OT  - Auxin
OT  - GH3
OT  - Jasmonate
OT  - Phytohormones
OT  - Salicylic acid
EDAT- 2021/12/04 06:00
MHDA- 2021/12/04 06:01
CRDT- 2021/12/03 20:19
PHST- 2021/06/01 00:00 [received]
PHST- 2021/11/15 00:00 [revised]
PHST- 2021/11/24 00:00 [accepted]
PHST- 2021/12/04 06:00 [pubmed]
PHST- 2021/12/04 06:01 [medline]
PHST- 2021/12/03 20:19 [entrez]
AID - S0031-9422(21)00388-5 [pii]
AID - 10.1016/j.phytochem.2021.113039 [doi]
PST - ppublish
SO  - Phytochemistry. 2022 Feb;194:113039. doi: 10.1016/j.phytochem.2021.113039. Epub 
      2021 Dec 1.