PMID- 34863210 OWN - NLM STAT- MEDLINE DCOM- 20211209 LR - 20211214 IS - 1742-6405 (Electronic) IS - 1742-6405 (Linking) VI - 18 IP - 1 DP - 2021 Dec 4 TI - Adverse events of inactivated COVID-19 vaccine in HIV-infected adults. PG - 92 LID - 10.1186/s12981-021-00416-1 [doi] LID - 92 AB - This study aims to evaluate the safety of inactivated COVID-19 vaccine among adult people living with HIV (PLWH). In total, 259 PLWH who received at least one dose of inactivated COVID-19 vaccine were enrolled, and post-vaccination adverse events (AEs) were evaluated seven days following each vaccination dose. The overall AE frequency was 22.8% after dose one, which was higher than after dose two (10.2%) (P < 0.001). No severe side event or vaccine safety concern was observed. Our finding was essential in reducing vaccine hesitancy among PLWH. CI - (c) 2021. The Author(s). FAU - Wu, Songjie AU - Wu S AD - Department of Nosocomial Infection Management, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. FAU - Zhang, Yubin AU - Zhang Y AD - Wuchang District Center for Disease Control and Prevention, Wuhan, Hubei, China. FAU - Ming, Fangzhao AU - Ming F AD - Wuchang District Center for Disease Control and Prevention, Wuhan, Hubei, China. FAU - Zou, Shi AU - Zou S AD - Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. FAU - Wu, Mengmeng AU - Wu M AD - Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. FAU - Guo, Wei AU - Guo W AD - Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, China. AD - Department of Pathology, School of Basic Medical Sciences, Wuhan University, Wuhan, China. FAU - Tang, Weiming AU - Tang W AD - Guangdong No. 2 Provincial People's Hospital, University of North Carolina at Chapel Hill Project-China, Guangzhou, 510095, China. Weiming_tang@med.unc.edu. AD - The University of North Carolina at Chapel Hill Project-China, Guangzhou, China. Weiming_tang@med.unc.edu. FAU - Liang, Ke AU - Liang K AUID- ORCID: 0000-0003-0490-5328 AD - Department of Nosocomial Infection Management, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. keliang@whu.edu.cn. AD - Department of Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China. keliang@whu.edu.cn. AD - Wuhan Research Center for Infectious Diseases and Cancer, Chinese Academy of Medical Sciences, Wuhan, China. keliang@whu.edu.cn. AD - Center of Preventing Mother-To-Child Transmission for Infectious Diseases, Zhongnan Hospital of Wuhan University, Wuhan, China. keliang@whu.edu.cn. AD - Department of Nosocomial Infection Management, Department of Infectious DiseasesCenter of Preventing Mother-To-Child Transmission for Infectious Diseases, Wuhan Research Center for Infectious Diseases and CancerChinese Academy of Medical Sciences, Zhongnan Hospital of Wuhan University, Wuhan, 430071, China. keliang@whu.edu.cn. LA - eng GR - 2017YFE0103800/the National Key Research and Development Program of China/ GR - 81903371/the National Nature Science Foundation of China/ GR - 2020KZDZX1047/Special Found on Prevention and Control of New Coronary Pneumonia in Guangdong Universities/ GR - 2018ZX10101-001-001-003/the National Science and Technology Major Project/ GR - cxpy2017043/Science and Technology Innovation Cultivation Fund of Zhongnan Hospital, Wuhan University/ GR - TFJC2018004/Medical Science Advancement Program (Basic Medical Sciences) of Wuhan University/ GR - R34MH119963/MH/NIMH NIH HHS/United States GR - PTXM2020008/Medical Science and Technology Innovation Platform Support Project of Zhongnan Hospital, Wuhan University/ PT - Journal Article DEP - 20211204 PL - England TA - AIDS Res Ther JT - AIDS research and therapy JID - 101237921 RN - 0 (COVID-19 Vaccines) SB - IM MH - Adult MH - *COVID-19 MH - COVID-19 Vaccines MH - *HIV Infections MH - Humans MH - SARS-CoV-2 MH - Vaccination Hesitancy PMC - PMC8643182 OTO - NOTNLM OT - Adverse event OT - COVID-19 OT - Inactivated vaccine OT - People living with HIV(PLWH) COIS- The authors declare that they have no competing interests. EDAT- 2021/12/06 06:00 MHDA- 2021/12/15 06:00 PMCR- 2021/12/04 CRDT- 2021/12/05 20:40 PHST- 2021/08/19 00:00 [received] PHST- 2021/11/17 00:00 [accepted] PHST- 2021/12/05 20:40 [entrez] PHST- 2021/12/06 06:00 [pubmed] PHST- 2021/12/15 06:00 [medline] PHST- 2021/12/04 00:00 [pmc-release] AID - 10.1186/s12981-021-00416-1 [pii] AID - 416 [pii] AID - 10.1186/s12981-021-00416-1 [doi] PST - epublish SO - AIDS Res Ther. 2021 Dec 4;18(1):92. doi: 10.1186/s12981-021-00416-1.