PMID- 34866483
OWN - NLM
STAT- MEDLINE
DCOM- 20220225
LR  - 20240404
IS  - 2150-1327 (Electronic)
IS  - 2150-1319 (Print)
IS  - 2150-1319 (Linking)
VI  - 12
DP  - 2021 Jan-Dec
TI  - Feasibility and Acceptability of a Type 2 Diabetes Prevention Intervention for 
      Mothers and Children at a Federally Qualified Healthcare Center.
PG  - 21501327211057643
LID - 10.1177/21501327211057643 [doi]
LID - 21501327211057643
AB  - BACKGROUND: Maternal obesity and gestational diabetes mellitus (GDM) contribute 
      to increased risk for type 2 diabetes mellitus (T2DM) among both mothers and 
      their offspring. Randomized trials demonstrated T2DM risk reduction in adults 
      following lifestyle behavior change and modest weight loss; the evidence base for 
      at-risk children remains limited. PURPOSE: Evaluate the feasibility, 
      acceptability, and preliminary efficacy of a T2DM prevention intervention for 
      mother-child dyads delivered by Federally Qualified Health Center staff. METHODS: 
      A group randomized design tested the effects of a behavioral lifestyle 
      intervention on T2DM risk factors in women with a history of GDM and their 8- to 
      12-year-old children. Mother-child dyads were recruited and randomized to 
      intervention or wait-listed control conditions. Intervention participants 
      completed the 13-week intervention; control participants received standard of 
      care. Baseline and 13-week measures assessed program acceptability and 
      feasibility, and explored effects on body weight, waist circumference, hemoglobin 
      A1c, and lifestyle behaviors. RESULTS: Forty-two dyads were randomized and 35 
      (83%) completed pre-/post-measurements. Participants and program leaders 
      positively rated content and engagement. Nearly all strongly agreed that 
      activities were enjoyable (97%), applicable (96%), useful (97%), and motivational 
      (96%). Attendance averaged 65% across 2 cohorts; delivery costs were 
      approximately $225/dyad. There were no significant differences in body weight, 
      BMI (or BMI z-score), waist circumference, hemoglobin A1c, diet quality, physical 
      activity, sleep, or home environment changes between intervention and control 
      groups. CONCLUSIONS: A family T2DM prevention program was feasibly delivered by 
      FQHC staff, and acceptable to mothers and children. Program efficacy will be 
      evaluated in an adequately powered clinical trial.
FAU - Hingle, Melanie
AU  - Hingle M
AUID- ORCID: 0000-0002-6696-5601
AD  - The University of Arizona, Tucson, AZ, USA.
FAU - Blew, Robert
AU  - Blew R
AD  - The University of Arizona, Tucson, AZ, USA.
FAU - James, Kyla
AU  - James K
AD  - El Rio Community Health Center, Tucson, AZ, USA.
FAU - Mockbee, Joy
AU  - Mockbee J
AD  - El Rio Community Health Center, Tucson, AZ, USA.
FAU - Palmer, Kelly N B
AU  - Palmer KNB
AD  - The University of Arizona, Tucson, AZ, USA.
FAU - Roe, Denise J
AU  - Roe DJ
AD  - The University of Arizona, Tucson, AZ, USA.
FAU - Saboda, Kathylynn
AU  - Saboda K
AD  - The University of Arizona, Tucson, AZ, USA.
FAU - Shaibi, Gabriel Q
AU  - Shaibi GQ
AD  - Arizona State University, Phoenix, AZ, USA.
FAU - Whitlatch, Shelley
AU  - Whitlatch S
AD  - El Rio Community Health Center, Tucson, AZ, USA.
FAU - Marrero, David
AU  - Marrero D
AD  - The University of Arizona, Tucson, AZ, USA.
LA  - eng
GR  - P30 CA023074/CA/NCI NIH HHS/United States
GR  - R34 DK118486/DK/NIDDK NIH HHS/United States
PT  - Journal Article
PT  - Randomized Controlled Trial
PT  - Research Support, N.I.H., Extramural
PL  - United States
TA  - J Prim Care Community Health
JT  - Journal of primary care & community health
JID - 101518419
SB  - IM
MH  - Adult
MH  - Child
MH  - Delivery of Health Care
MH  - *Diabetes Mellitus, Type 2/prevention & control
MH  - *Diabetes, Gestational/prevention & control
MH  - Feasibility Studies
MH  - Female
MH  - Humans
MH  - Life Style
MH  - Mothers
MH  - Pregnancy
PMC - PMC8652912
OTO - NOTNLM
OT  - child
OT  - diabetes
OT  - diabetes mellitus
OT  - gestational
OT  - lifestyle
OT  - mothers
OT  - primordial prevention
OT  - type 2
COIS- Declaration of Conflicting Interests: The author(s) declared no potential 
      conflicts of interest with respect to the research, authorship, and/or 
      publication of this article.
EDAT- 2021/12/07 06:00
MHDA- 2022/02/26 06:00
PMCR- 2021/12/05
CRDT- 2021/12/06 08:47
PHST- 2021/12/06 08:47 [entrez]
PHST- 2021/12/07 06:00 [pubmed]
PHST- 2022/02/26 06:00 [medline]
PHST- 2021/12/05 00:00 [pmc-release]
AID - 10.1177_21501327211057643 [pii]
AID - 10.1177/21501327211057643 [doi]
PST - ppublish
SO  - J Prim Care Community Health. 2021 Jan-Dec;12:21501327211057643. doi: 
      10.1177/21501327211057643.