PMID- 34869775 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220428 IS - 2356-7651 (Print) IS - 2314-6176 (Electronic) IS - 2314-6176 (Linking) VI - 2021 DP - 2021 TI - A Comparative Study of Hematological Parameters of Endurance Runners at Guna Athletics Sport Club (3100 Meters above Sea Level) and Ethiopian Youth Sport Academy (2400 Meters above Sea Level), Ethiopia. PG - 8415100 LID - 10.1155/2021/8415100 [doi] LID - 8415100 AB - INTRODUCTION: Endurance running performance is dependent upon hematological, physiological, anthropometrical, diet, genetic, and training characteristics. Increased oxygen transport and efficiency of tissue in extracting oxygen are the major determinants to competitions that require endurance. Thus, altitude training is often employed to increase blood oxygen-carrying capacity to improve sea-level endurance performance. This study aimed to compare hematological parameters of endurance runners' training at different clubs with different altitudes (Guna Athletics Sport Club at Guna (3100 meter above sea level) and Ethiopian Youth Sport Academy at Addis Ababa (2400 meter above sea level)). METHODS: A comparative cross-sectional study was conducted at GASC and EYSA. Data were collected from a total of 102 eligible study subjects (26 runners and 25 controls at Guna and 26 runners and 25 controls at Addis Ababa) from May to October 2019. About 3 ml of the venous blood was drawn from the antecubital vein by aseptic procedure and analyzed using a hematology analyzer (DIRUI BCC-3000B, China). One-way ANOVA and independent-sample t-tests were used to compare means. RESULT: Male runners in Guna had significantly higher hemoglobin (Hgb), mean corpuscular hemoglobin (MCH), mean corpuscular hemoglobin concentration (MCHC), and white blood cell (WBC) count than male runners in Addis Ababa. Besides, female runners in Guna had significantly higher MCH and MCHC than female runners in Addis Ababa. However, there were no significant differences between Guna and Addis Ababa runners in red blood cell (RBC) count, Hct, MCV, and platelet count in both sexes, while Hgb and WBC count in females. CONCLUSION: Decisively, Guna Athletics Sport Club endurance runners had significantly higher hematological parameters than Ethiopian Youth Sport Academy endurance runners. This provides invaluable information for coaches and sport physicians to monitor the hematological profile and the health status of an athlete living and training at different altitudes. CI - Copyright (c) 2021 Zelalem Tilahun Muche et al. FAU - Tilahun Muche, Zelalem AU - Tilahun Muche Z AUID- ORCID: 0000-0002-6563-9302 AD - Department of Medical Physiology, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia. FAU - Haile Wondimu, Diresibachew AU - Haile Wondimu D AD - Department of Medical Physiology, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia. FAU - Bayissa Midekssa, Milkessa AU - Bayissa Midekssa M AD - Department of Sport Science, Sport Science Academy, Haramaya University, Haramaya, Ethiopia. FAU - Chekol Abebe, Endeshaw AU - Chekol Abebe E AD - Department of Medical Biochemistry, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia. FAU - Mengie Ayele, Teklie AU - Mengie Ayele T AD - Department of Pharmacy, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia. FAU - Abebe Zewdie, Ediget AU - Abebe Zewdie E AD - Department of Medical Physiology, College of Health Sciences, Debre Tabor University, Debre Tabor, Ethiopia. LA - eng PT - Journal Article DEP - 20211124 PL - United States TA - J Sports Med (Hindawi Publ Corp) JT - Journal of sports medicine (Hindawi Publishing Corporation) JID - 101633176 PMC - PMC8635926 COIS- The authors declare no competing interests. EDAT- 2021/12/07 06:00 MHDA- 2021/12/07 06:01 PMCR- 2021/11/24 CRDT- 2021/12/06 09:22 PHST- 2021/07/03 00:00 [received] PHST- 2021/10/19 00:00 [revised] PHST- 2021/11/05 00:00 [accepted] PHST- 2021/12/06 09:22 [entrez] PHST- 2021/12/07 06:00 [pubmed] PHST- 2021/12/07 06:01 [medline] PHST- 2021/11/24 00:00 [pmc-release] AID - 10.1155/2021/8415100 [doi] PST - epublish SO - J Sports Med (Hindawi Publ Corp). 2021 Nov 24;2021:8415100. doi: 10.1155/2021/8415100. eCollection 2021.